Patents Assigned to TECNIMEDE, SOCIEDADE TÉCNICO-MEDICINAL, SA
  • Processes for the preparation of pharmaceutically acceptable salts of (R)-Pirlindole and (S)-Pirlindole
    Patent number: 11008328
    Abstract: The present invention relates to an improved process for the preparation of Pirlindole enantiomers, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 18, 2021
    Assignee: TECNIMEDE, SOCIEDADE TÉCNICO-MEDICINAL, SA
    Inventors: Carla Patrícia Da Costa Pereira Rosa, João Carlos Ramos Damil, Ana Vanessa Cordeiro Simões, João Pedro Silva Serra
  • Processes for the preparation of pharmaceutically acceptable salts of (R)-Pirlindole and (S)-Pirlindole
    Patent number: 11008327
    Abstract: The present disclosure relates to an improved process for the synthesis of piperazine ring, particularly for the preparation of heterocyclic compounds useful as intermediates in the synthesis of pyrazinocarbazoles such as the antidepressant Pirlindole. The process described is useful to prepare Pirlindole enantiomers, or a pharmaceutically accepted salt thereof.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 18, 2021
    Assignee: TECNIMEDE, SOCIEDADE TÉCNICO-MEDICINAL, SA
    Inventors: Carla Patrícia Da Costa Pereira Rosa, João Carlos Ramos Damil, Ana Vanessa Cordeiro Simões, João Pedro Silva Serra