Patents Assigned to Teikoku Chemical Industry Co., Ltd.
  • Patent number: 6831190
    Abstract: The invention relates to novel and valuable intermediate compounds of the general formula (VIII) which can be used for the preparation of novel compounds comprising an antibacterial action, especially with a strong antibacterial action against helicobacter pylori, and pharmaceutically acceptable salts thereof. In the general formula (VIII) X is hydrogen or halogen, Y is hydrogen or a substituted or unsubstituted aralkyloxycarbonyl group having 8-19 carbon atoms, Z is hydrogen, a substituted aralkyloxycarbonyl group having 8-19 carbon atoms or a substituted alkoxycarbonyyl group having 2-19 carbon atoms, except that X, Y and Z are all hydrogen.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: December 14, 2004
    Assignee: Teikoku Chemical Industries Co., Ltd.
    Inventors: Osamu Kamoda, Hiromichi Fujiwara, Toshiharu Yanagi
  • Patent number: 6444703
    Abstract: The present invention relates to a pharmaceutical composition which is appropriate for eradication or extermination of Helicobacter pylori wherein [4-[4-(4-methylbenzyloxycarbonyl)phenyl[phenyl trans-4-guanidinomethylcyclohexanecarboxylate or an acid addition salt thereof are compounded and it also relates to a complex consisting them.
    Type: Grant
    Filed: August 12, 1998
    Date of Patent: September 3, 2002
    Assignee: Teikoku Chemical Industries Co., Ltd.
    Inventors: Osamu Kamoda, Toshiharu Yanagi, Eiji Tamaki, Seiji Sato, Jun-ichi Mizoguchi
  • Patent number: 6284791
    Abstract: A compound represented by general formula (I-2) or a pharmaceutically acceptable acid-addition salt thereof, useful as an anti-microbial against Helicobacter pylori and as a medicinal composition for treating Helicobacter pylori infection, wherein Ar represents phenyl, biphenyl or naphthyl each having a at least one substituent selected from the group consisting of halogen, cyano, nitro, carboxy, C1-C18 alkyl, C1-C18 alkoxy, C3-C18 cycloalkyl, C7-C18 aralkyl, C8-C18 arylalkenyl, C7-C18 aralkyloxy, optionally substituted phenoxy, optionally substituted C2-C19 alkoxycarbonyl, and optionally substituted C8-C19 aralkyloxycarbonyl, provided the case where Ar represents phenyl substituted by halogen, cyano, nitro, carboxy, C1-C18 alkyl, optionally substituted C2-C19 alkoxycarbonyl or C8-C19 aralkyloxycarbonyl is expected.
    Type: Grant
    Filed: February 28, 1997
    Date of Patent: September 4, 2001
    Assignee: Teikoku Chemical Industries Co., Ltd.
    Inventors: Osamu Kamoda, Hiromichi Fujiwara, Toshiharu Yanagi
  • Patent number: 6103686
    Abstract: A chelating composition containing an aliphatic polycarboxylic acid of the following formula (I): ##STR1## wherein A is an imino group or an oxygen atom, R is a hydrogen atom or a hydroxyl group, and n is 0 or 1, or the salt thereof and sugar or saccharic acid of 4 to 12 carbon atoms at such a ratio as enables the components to manifest synergistic effects is provided. This chelating composition is capable of effectively sequestering a metal ion and preventing the metal ion from being insolubilized without causing pollution of the environment.
    Type: Grant
    Filed: July 16, 1998
    Date of Patent: August 15, 2000
    Assignees: Nippon Shokubai Co. Ltd., Teikoku Chemical Industries Co., Ltd.
    Inventors: Miaki Asakawa, Yasutaka Sumida, Masatoshi Shimomura, Shuichi Okuno, Tadanobu Morimoto, Masanao Morita, Hitoshi Suenaga
  • Patent number: 5395552
    Abstract: A ferroelectric liquid crystal electro-optical device comprises a pair of plates having driving electrodes and ferroelectric liquid crystal material having a negative dielectric anisotropy. The ferroelectric liquid crystal material comprises a ferroelectric liquid crystal composition 10 to 80% by weight of a compound of the general formula: ##STR1## wherein R.sub.1 represents a straight-chain alkyl or alkoxy group, or an alkyl, alkoxy, alkoxyalkyl or acyloxy group each having an asymmetric carbon atom, and R.sub.2 represents a straight-chain alkyl group having an assymmetric carbon.
    Type: Grant
    Filed: February 10, 1993
    Date of Patent: March 7, 1995
    Assignees: Seiko Instruments Inc., Teikoku Chemical Industry Co., Ltd.
    Inventors: Hitoshi Suenaga, Masaaki Taguchi
  • Patent number: 5231523
    Abstract: A liquid crystal element has a pair of opposed substrates, electrodes thereon, and a ferroelectric liquid crystal sealed between the substrates. A film of a conductive organic compound or a mixture of a conductive organic compound and another organic compound is disposed on the substrate surface, optionally via an orienting film. The conductive organic compound is typically a charge-transfer complex. The film may be formed by an LB method, coating, vapor phase polymerization or electrolytic polymerization. The element has improved optical bistability, contrast, and response.
    Type: Grant
    Filed: August 20, 1992
    Date of Patent: July 27, 1993
    Assignees: TDK Corporation, Shunsuke Kobayashi, Teikoku Chemical Industry, Co., Ltd., Japan Carlit Co., Ltd.
    Inventors: Kenji Nakaya, Shunsuke Kobayashi, Hitoshi Suenaga, Makoto Ebisawa
  • Patent number: 5143935
    Abstract: A benzamide derivative represented by the formula: ##STR1## having a promoting activity of gastrointestinal tract and pharmacentical composition containing the same.
    Type: Grant
    Filed: October 16, 1991
    Date of Patent: September 1, 1992
    Assignee: Teikoku Chemical Industry Co., Ltd.
    Inventors: Hiromichi Fujiwara, Akihiko Ogawa, Hideyo Sakiyama, Toshiaki Tamura
  • Patent number: 5110496
    Abstract: An optically active liquid crystal compound which is represented by the formula: ##STR1## wherein R.sub.1 and R.sub.2 each represents an alkyl or aralkyl group of 4-18 carbon atoms, R.sub.3 represents a haloalkyl group, X represents O, COO, OCO, CO or a single bond, Y represents COO, OCO, CH.sub.2 O or OCH.sub.2, Z represents COO or O, (A) represents a cyclic group shown by ##STR2## (B) represents a cyclic group shown by ##STR3## and l shows that the cyclic groups are substituted by at least one halogen atom.
    Type: Grant
    Filed: March 1, 1991
    Date of Patent: May 5, 1992
    Assignees: Showa Shell Sekiyu Kabushiki Kaisha, Teikoku Chemical Industry Co., Ltd.
    Inventors: Hiroyuki Mogamiya, Noriko Yamakawa, Yoshiichi Suzuki, Hitoshi Suenaga, Yasuhiro Hasegawa
  • Patent number: 4990604
    Abstract: Method for the production of asialoganglioside related compounds of the formula (I). ##STR1## wherein R.sup.1 is hydrogen or benzoyl, R.sup.2 is hydrogen or acetyl, R.sup.3 is hydrogen, acetyl, .beta.-D-galactopyranosyl or 2,3,4,6-tetra-O-acetyl-.beta.-D-galactopyranosyl, R.sup.7 and R.sup.8 are individually alkyl having 1 to 30 carbon atoms and Ac is acetyl.
    Type: Grant
    Filed: February 24, 1986
    Date of Patent: February 5, 1991
    Assignees: Rikagaku Kenkyusho, Kanto Ishi Pharmaceutical Co., Ltd., Teikoku Chemical Industry Co., Ltd.
    Inventors: Tomoya Ogawa, Mamoru Sugimoto, Yoshiyasu Shitori, Toshio Horisaki, Tadami Shinuchi
  • Patent number: 4980082
    Abstract: This invention relates to new optically active pyrimidinylphenyl ester compounds, having a liquid crystal phase of cholesteric and/or smectic C* phase, of the formula: ##STR1## wherein R* represents an optically-active alkyl group having an asymmetric carbon atom which is ##STR2## where R.sup.0 is a straight chain alkyl group of 2 to 6 carbon atoms, R.sup.1 is a straight chain alkyl group of 1 to 5 carbon atoms, R.sup.2 is a straight chain alkyl group of 1 to 2 carbon atoms, R.sup.3 is a straight chain alkyl group of 1 to 6 carbon atoms and n is 0 or 1, R presents a straight-chain alkyl group of 7 or 8 carbon atoms or a straight-chain alkoxy group of 7 or 8 carbon atoms and A represents ##STR3## or --O--.
    Type: Grant
    Filed: September 1, 1987
    Date of Patent: December 25, 1990
    Assignees: Seiko Instruments Inc., Teikoku Chemical Industry Co., Ltd.
    Inventors: Kazumasa Ohba, Hiroshi Nonoguchi, Masaaki Taguchi, Takamasa Harada
  • Patent number: 4725688
    Abstract: The present invention is an optically active liquid crystal compound shown in the following general formula; ##STR1## [wherein, A and B respectively show one of --, --O--, ##STR2## (-- shows direct bond), one of R.sub.1 and R.sub.2 shows direct chain alkyl group and the other one shows either alkyl group having asymmetric carbon atom or alkoxy alkyl group having asymmetric carbon atom and ether bonding. Also, onto the asymmetric carbon atom, one of the groups --CH.sub.3, --CN, --Cl is added.]It is clear that there are many compounds in these liquid crystal compounds, that show Sm C* phase in a wide temperature range close to room temperature and that have high response speed.
    Type: Grant
    Filed: February 6, 1986
    Date of Patent: February 16, 1988
    Assignees: Seiko Instruments Inc., Teikoku Chemical Industry Co., Ltd.
    Inventors: Masaaki Taguchi, Takamasa Harada, Hitoshi Suenaga
  • Patent number: 4710585
    Abstract: A liquid crystal compound represented by the following general formula:R*O--A--R or R*COO--A--Rwherein R* stands for an alkyl group having an asymmetric carbon atom, R stands for a linear alkyl group, and A stands for ##STR1##
    Type: Grant
    Filed: June 10, 1985
    Date of Patent: December 1, 1987
    Assignees: Seiko Instruments & Electronics Ltd., Teikoku Chemical Industry Co., Ltd.
    Inventors: Masaaki Taguchi, Hitoshi Suenaga
  • Patent number: 4643842
    Abstract: A liquid crystal composition comprising at least one optically active liquid crystal compound represented by the following general formula: ##STR1## wherein R.sub.2 stands for a linear alkyl group and R.sub.1 * stands for an alkoxy or acyloxy group having an asymmetric carbon atom,and at least one optically active liquid crystal compound represented by the following general formula: ##STR2## wherein R.sub.3 * stands for an alkyl group having an asymmetric carbon atom and R.sub.4 stands for a linear alkyl group.
    Type: Grant
    Filed: March 28, 1985
    Date of Patent: February 17, 1987
    Assignees: Seiko Instruments & Electronics Ltd., Teikoku Chemical Industry Co., Ltd.
    Inventors: Masaaki Taguchi, Hitoshi Suenaga
  • Patent number: 4633012
    Abstract: A liquid crystal compound represented by the following general formula: ##STR1## wherein m is a number from 0 to 10, n is a number from 5 to 14, and C having an asterisk indicates an asymmetric carbon atom.
    Type: Grant
    Filed: June 10, 1985
    Date of Patent: December 30, 1986
    Assignees: Seiko Instruments & Electronics Ltd., Teikoku Chemical Industry Co., Ltd.
    Inventors: Masaaki Taguchi, Takamasa Harada, Hitoshi Suenaga
  • Patent number: 4478995
    Abstract: A complex of an acid addition salt of (2'-benzyloxycarbonyl)phenyl trans-4-guanidinomethylcyclohexanecarboxylate and a cyclodextrin. The complex is useful for the treatment of ulcers.
    Type: Grant
    Filed: August 27, 1982
    Date of Patent: October 23, 1984
    Assignee: Teikoku Chemical Industry Co., Ltd.
    Inventors: Masamitu Shinoda, Ikuo Tanaka, Tadahiko Yasuda, Isao Nakajima, Tutomu Adachi, Giichi Ikeda
  • Patent number: 4348410
    Abstract: A compound of the formula: ##STR1## wherein R.sub.1 represents a vanilyl, napthyl, pyridyl or .alpha.-tocopheryl group, or a group of the formula, ##STR2## wherein R.sub.2 represents a hydrogen atom, a lower alkoxy, formyl, lower alkanoyl or phenyl group, or a group of the formula --(CH.sub.2).sub.n COOR.sub.3, wherein R.sub.3 represents a hydrogen atom, a lower alkyl, phenyl, benzyl, anisyl or lower alkoxycarbonylmethyl group, and n represents an integer of 0 to 2, or a pharmaceutically acceptable salt thereof is effective for use as an anti-ulcer agent.
    Type: Grant
    Filed: September 15, 1980
    Date of Patent: September 7, 1982
    Assignees: Nippon Chemiphar Co., Ltd., Teikoku Chemical Industry Co., Ltd.
    Inventors: Mutsumi Muramatsu, Toshio Satoh, Yukio Yanagimoto, Tadami Shinuchi, Toshio Nakajima, Isao Nakajima
  • Patent number: 3983134
    Abstract: Ureylenethiophanes and their related compounds of the formula: ##SPC1##Having a cis-configuration on the ureylene or thioureylene juncture, which are useful as the intermediates in the synthesis of biologically active biotin and its related compounds, can be produced selectively by reacting the corresponding compounds of the formula: ##SPC2##With isocyanates or isothiocyanates wherein R is a hydrogen atom, an alkyl group or an aralkyl group, R.sub.1 and R.sub.2 are each a hydrogen atom or an aliphatic hydrocarbon group bearing or not a carboxyl group or any other group convertible thereto at the terminal position, X is a halogen atom, Y is an oxygen atom or a sulfur atom and Z is an oxygen atom, a sulfur atom, a sulfinyl group or a sulfonyl group.
    Type: Grant
    Filed: August 5, 1975
    Date of Patent: September 28, 1976
    Assignee: Teikoku Chemical Industry Co., Ltd.
    Inventors: Masanao Matsui, Kenji Mori, Takeshi Kitahara, Seiichi Kitamura, Kazumasa Ohba
  • Patent number: 3962267
    Abstract: The dental cement composition comprises an aqueous resin composition prepared by the copolymerization of 3-butene-1,2,3-tricarboxylic acid and an .alpha.,.beta.-olefinic unsaturated monocarboxylic acid and, when desired, an additional polymerizable monomer as well as a metal oxide. The dental cement composition possesses compressive strength.
    Type: Grant
    Filed: July 11, 1974
    Date of Patent: June 8, 1976
    Assignees: Shofu Dental Corporation, Teikoku Chemical Industry Co., Ltd.
    Inventors: Narishige Suzuki, Yoshihiro Morino, Yoshitaka Hashiguchi, Tunehiro Segawa
  • Patent number: 3939202
    Abstract: Polyene compounds of the formula: ##EQU1## wherein R' is protected or unprotected hydroxyl or a group of the formula: ##EQU2## (in which R" and R"' are each carboxyl or a group convertible into carboxyl on hydrolysis), m is a positive integer and n is 0 or a positive integer, which are useful as intermediates in the synthesis of coenzyme Q, can be produced advantageously through a step for the dehydration of a compound of the formula: ##EQU3## wherein R', m and n are each as defined above.
    Type: Grant
    Filed: January 29, 1974
    Date of Patent: February 17, 1976
    Assignee: Teikoku Chemical Industry Co., Ltd.
    Inventors: Masanao Matsui, Seiichi Kitamura, Masahiro Morioka