Abstract: A composition for use in wound healing and therefor is disclosed. The multiple components of fish fertilized roe are extracted. By virtue of its ability as an anti-oxidant to eliminate free radicals, inhibition of tyrosinase activity and facilitate the mass secretion of collagen from skin fibroblasts in order to promote skin whitening, anti-aging and wound healing. Accordingly, skin all-round repair is achieved, which is used as a cosmetic raw material and a wound dressing.