Abstract: An osteosynthesis device that is both resorbable and radiopaque, produced using gradually degrading materials, includes at least one plate and a set of screws made of resorbable material, in which the plate consists of a composite mixture including i) a resorbable polymer or copolymer compound and ii) an inorganic filler that consists of at least one resorbable ceramic. The screws can be made of resorbable polymer, or of a composite mixture with at least one resorbable ceramic. The device is totally resorbable and radiopaque, and it offers a high level of safety, ensuring a strong and durable fixation of the screws to the plate and in the bone during the entire period needed for bone uniting.

Abstract: The invention relates to a device for the injection of a bone cement. The invention comprises a container provided with one end including an outlet and a second end that receives a piston. The piston is moved by means of an injection screw that projects from the container body and engages with gripping means comprising injection screw rotation means that can self-lock depending on the pressure exerted inside the container body, said rotation means comprising a handle which is provided with a passage that receives the injection screw and which is hinged thereto by means of a pair of male/female disks. One disk is known as the drive disk and moves integrally with the rotation movements of the handle, while the other disk is known as the driven disk, said drive disk coming into contact with the driven disk in response to a compressive force exerted on the distal part of the injection screw.

Abstract: The invention relates to a system for preparing a polymerized bone cement, including two components reacting with each other when they are mixed to form a solid polymer material. The first component may include a biocompatible acrylic polymer and an initiator capable of initiating a polymerization reaction. The second component may include a monomer capable of dissolving an acrylic polymer, a polymerization activator and a polymerization inhibitor, system in which the second component also includes a biocompatible acrylic polymer dissolved in said monomer, identical or different from the polymer of the first component with an average molar mass greater than 1,000,000 g/mol and a residual initiator content of less than 0.1% to form a gel with determined viscosity. Another object of the invention is a composition designed to constitute the second component of as system used to prepare such cement.

Abstract: A ready-for-use polymer cement spacer device for the replacement of a permanent joint prosthesis during a two-stage replacement, includes a shank includes for attachment for placing to the supporting bone and a head in the joint region. The spacer device includes two complementary members incorporating rigid members for assembly between them, the first member being loaded with a first active substance and the second member being loaded with a second active substance. The first and second active substances are preferably antibiotics, selected from gentamycin, trobamycin, vancomycin, erythromycin, fucidin, tetracycline or other suitable antibiotics. The temporary joint implant maintains a suitable space for the time necessary for the operation of replacing a permanent prosthesis to prevent tissues from occupying the space released by removal of the permanent prosthesis and ensures effective treatment of resistant infections by local treatment of the joint area through at least two different active substances.

Abstract: A fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. A device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 70% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer, and b) approximately from 15 to 30% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as a barium sulphate and zirconium dioxide, in a mixture with a calcium phosphate, for example hydroxyapatite.

Abstract: The invention provides a fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. The invention also provides a device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 60% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer and b) approximately from 15 to 40% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as barium sulfate and zirconium dioxide, in a mixture with a calcium phosphate, for example apatite hydroxide.

Abstract: The present invention relates to a method for preparing a biodegradable piece for medical use including the steps of: a) preparing a mixture including glycerol and sebacic acid, b) pouring said mixture into a one-piece mould made of elastic material, c) placing the mould containing said mixture on a support, d) placing the support into a chamber with controlled temperature and vacuum level until a polymer having the desired consistency is obtained, e) removing the support from the chamber and allowing it to cool down to room temperature, and f) removing the piece thus obtained from the mould.

Abstract: The invention relates to an implantable orthesis for knee arthrodesis comprising a tibial anchoring head (1), a femoral anchoring head (2), an intramedullary tibial rod (3) and an intramedullary femoral rod (4). The anchoring heads (1, 2) are of a shape which is without symmetry of revolution and are splayed laterally in a front plane from the intramedullary rod (3, 4). They are rigidly assembled to one another.

Abstract: A solid powder product with a Ca/P ratio of between 1.40 and 1.90 is prepared from tricalcium phosphate and tetracalcium phosphate. An aqueous solution containing calcium ions and phosphate ions with a Ca/P ratio higher than 0.20 and lower than 0.50 is prepared. The aqueous solution and the solid powder product and optionally water are mixed to obtain a mixture with a liquid/solid weight ratio of between 0.30 and 0.65 and a resulting paste with a Ca/P ratio of between 1.50 and 1.67.