Abstract: A method of determining antimicrobial activity of an agent can include providing a well, wherein the well contains at least one antimicrobial agent, the well further including at least two electrodes. A sample of a microbe can be added into the well and a voltage pulsed between the electrodes. An electrical property can be sampled and recorded. In another aspect, a method of identifying at least one microbe includes taking a sample containing the at least one microbe, isolating the at least one microbe from the sample, dividing the at least one microbe into at least one well, wherein each well contains at least one antimicrobial agent and at least two electrodes. A voltage is pulsed between the at least two electrodes, an electrical property is sampled during the pulsing and recorded. In another aspect, a diagnostic device for detecting at least one microbe is presented.
Type:
Application
Filed:
December 4, 2013
Publication date:
June 12, 2014
Applicants:
Texas State University, Telemedicine Up Close, Inc. dba DxUpClose
Inventors:
Cynthia S. NICKEL, Clois E. POWELL, James R. BIARD, William A. STAPLETON, Gary M. ARON, Jeanette HILL, Ray G. COOK, Daniel M. JUSTISS, Frederick J. STRIETER, Andrei M. MANOLIU
Abstract: A method of determining antimicrobial activity of an agent can include providing a well, wherein the well contains at least one antimicrobial agent, the well further including at least two electrodes. A sample of a microbe can be added into the well and a voltage pulsed between the electrodes. An electrical property can be sampled and recorded. In another aspect, a method of identifying at least one microbe includes taking a sample containing the at least one microbe, isolating the at least one microbe from the sample, dividing the at least one microbe into a at least one well, wherein each well contains at least one antimicrobial agent and at least two electrodes. A voltage is pulsed between the at least two electrodes, an electrical property is sampled during the pulsing and recorded. In another aspect, a diagnostic device for detecting at least one microbe is presented.
Type:
Application
Filed:
May 4, 2012
Publication date:
January 17, 2013
Applicants:
Texas State University, Telemedicine Up Close, Inc. dba DxUpClose
Inventors:
Cynthia S. Nickel, Clois E. Powell, James R. Biard, William A. Stapleton, Gary M. Aron, Jeanette Hill, Ray G. Cook, Daniel M. Justiss, Frederick J. Strieter, Wayne T. Kilian, Andrei M. Manoliu