Abstract: A disposable flow-through refrigeration system includes an evaporator chamber containing a refrigerant, which, during system operation, evaporates to form a vapor; an evacuated absorber chamber including sorbent for receiving the vapor, a heat sink material in thermal contact with the sorbent, and a means for preventing vapor flow from evaporator to absorber until operation of the refrigeration system. The system also includes a primary volume of dispensable product and a product reservoir in fluid communication with each other. The system includes a dispensing means configured to enable controlled withdrawal of a secondary volume of product contained in the reservoir which includes a flow path from the primary volume to the dispensing means. At least one wall of the flow path is in thermal contact with an outer surface of the evaporator chamber during operation of the refrigeration system.