Patents Assigned to Tengion, Inc.
  • SMOOTH MUSCLE CELL CONSTRUCTS
    Publication number: 20150030657
    Abstract: The present invention relates to the regeneration, reconstruction, augmentation or replacement of luminal organs or tissue structures in a subject in need using scaffolds seeded with autologous or non-autologous cell populations that are or are not derived from the corresponding organ or tissue structure that is the subject of the regeneration, reconstruction, augmentation or replacement.
    Type: Application
    Filed: May 3, 2011
    Publication date: January 29, 2015
    Applicant: TENGION, INC.
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha, Jacob E. Shokes, Teresa B. Burnette, Sarah A. Boyd, Craig R. Halberstadt, Dominic M. Justewicz, Elias A. Rivera, Wendy Sharp, Neil F. Robbins
  • SCAFFOLDS FOR ORGAN RECONSTRUCTION AND AUGMENTATION
    Publication number: 20140107804
    Abstract: Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.
    Type: Application
    Filed: September 17, 2013
    Publication date: April 17, 2014
    Applicant: Tengion, Inc.
    Inventors: Timothy A. Bertram, Andrew Bruce, Deepak Jain, Manuel J. Jayo, John W. Ludlow, Darell McCoy, Richard Payne, Namrata D. Sangha, Oluwatoyin A. Knight
  • Scaffolds for organ reconstruction and augmentation
    Patent number: 8696760
    Abstract: Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: April 15, 2014
    Assignee: Tengion, Inc.
    Inventors: Timothy A. Bertram, Andrew Bruce, Deepak Jain, Manuel J. Jayo, John W. Ludlow, Darell McCoy, Richard Payne, Namrata D. Sangha, Oluwatoyin A. Knight
  • THERAPEUTIC FORMULATIONS
    Publication number: 20130330364
    Abstract: The present invention concerns therapeutic formulations containing active agents, such bioactive cell populations, and methods of making and using the same.
    Type: Application
    Filed: November 10, 2011
    Publication date: December 12, 2013
    Applicant: TENGION, INC.
    Inventors: Joydeep Basu, Richard Payne, Neil F. Robbins, Oluwatoyin A. Knight, Deepak Jain, Craig R. Halberstadt, Monica A. Serban
  • CELL SCAFFOLD CONSTRUCTS
    Publication number: 20130173015
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Application
    Filed: November 20, 2012
    Publication date: July 4, 2013
    Applicant: Tengion, Inc.
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • ISOLATED RENAL CELLS AND USES THEREOF
    Publication number: 20130149347
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Application
    Filed: October 26, 2012
    Publication date: June 13, 2013
    Applicant: TENGION, INC.
    Inventor: Tengion, Inc.
  • Cell-scaffold constructs
    Patent number: 8337485
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: December 25, 2012
    Assignee: Tengion, Inc.
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • Isolated renal cells and uses thereof
    Patent number: 8318484
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: November 27, 2012
    Assignee: Tengion, Inc.
    Inventors: Sharon C. Presnell, Andrew Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • Scaffolds for organ reconstruction and augmentation
    Patent number: 7918897
    Abstract: Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.
    Type: Grant
    Filed: February 12, 2007
    Date of Patent: April 5, 2011
    Assignee: Tengion, Inc.
    Inventors: Timothy A. Bertram, Andrew Bruce, Deepak Jain, Manuel J. Jayo, John W. Ludlow, Darell McCoy, Richard Payne, Namrata D. Sangha