Abstract: Intelligent system (1) for monitoring a reference environment, suitable for multisensorial interaction with a user, comprising: at least one multiprotocol control unit (2), provided with at least one internal wireless modem (16), a power supply connector (71), a microprocessing unit (15), RAM memory means (13), program memory means (12) and data memory means (14); at least one modem, respectively a modem-router, external (30) with respect to the control unit (2) and operatively connected to the same; wherein said system (1) further comprises: sensor means, internal with respect to the control unit (2); a plurality of actuator means external (20) with respect to the control unit (2); sensor means external with respect the control unit (2); wherein: said sensor means internal with respect to the control unit (2) which are, individually or in combination, at least a microphonic sensor (3), a relative humidity sensor (4), a temperature sensor (5), respectively an atmospheric pressure sensor (6) or the like