Abstract: An endoscopic vessel harvester includes a vessel keeper for capturing a target vessel within a tunnel that has been dissected along the target vessel. A cutter member cuts and cauterizes side branches while the target vessel is slidably captured in the vessel keeper. A spray nozzle carried by the vessel keeper delivers a preservative fluid via a manual control valve and a conduit. The preservative fluid is sprayed on the target vessel proximate a respective side branch immediately after being cauterized. Thus, a harvested vessel is bathed in preservative fluid prior to being actually removed from the body, enhancing endothelial preservation from cascading events.

Abstract: A pump drive unit has an openable housing that accommodates a disposable impeller unit which is pre-connected with tubing, while maintaining the tight tolerances and close spacing. A levitation system (magnets and sensors), drive motor and drive magnets, and control electronics are all re-usable and housed within relatively permanent structures. In one embodiment, a hinged top separates the levitating magnets to allow the impeller unit to be captured and retained with positional accuracy and in close proximity to the desired locations when the hinged top is closed. The top may be separated into sections covering unequal arcs to coincide with the organization of the magnetic subcomponents in the upper drive unit housing.

Abstract: Apparatus use with a perfusion system, the apparatus including a subject simulator for simulating subject. The subject simulator includes a circulatory system having an inlet line for receiving fluid from the perfusion system, an outlet line for transferring fluid to the perfusion system, at least on sensor for sensing at least one fluid property and at least one control device coupled to at least one of the inlet line and the outlet line. In use this, allows the control device to manipulate the at least on fluid property based at least partially on signals from the at least one sensor, to thereby simulate a least one of compliance and resistance of the simulated subject.

Abstract: A vessel harvesting apparatus is provided for removing a vessel from a patient. An endoscopic instrument has a distal end with a vessel harvesting tip and has a proximal end with a handle. The endoscopic instrument has an insufflation channel adapted to receive an insufflation gas from a regulated source at the proximal end. The insufflation channel has an outlet at the distal end adapted to expel the insufflation gas subcutaneously in the patient. A damping device has a flexible bladder with an inside space in fluid communication with the insufflation channel. The inside space has a volume that varies between a rest volume and an inflated volume in response to an amount of insufflation gas flowing to or from the flexible bladder.

Abstract: A single-lumen, multi-stage cannula particularly adapted for venous drainage during cardiac surgery includes a first stage comprising a longitudinal tubular tip having a first plurality of fenestrations to provide an axial flow at a proximal end of the tip. A second stage coaxial with the first stage comprises a nozzle section having an outer lumen wall and an inner annular wall. A central passage disposed within the inner annular wall continues the axial flow from the first stage. A plurality of outer passages is disposed between the outer lumen wall and the inner annular wall so that the inner annular wall isolates the central passage from the outer passages. The outer lumen wall includes a plurality of second fenestrations, wherein each second fenestration supplies fluid from a second region outside the cannula to a respective outer passage. The outer passages have respective outlets arranged to provide an injected flow substantially parallel to the axial flow.

Abstract: A blood parameter measurement cassette or other device is configured to control incidental liquid discharged during the device's calibration process. The cassette includes optical sensors which are chemically responsive to blood constituents and require calibration with a blood parameter monitoring device prior to use in a medical procedure. During the calibration process, an incidental amount of a liquid may be expelled from the cassette. The present invention is directed towards controlling the expelled liquid by absorbing it using an absorbent material disposed on the exterior of the cassette's main body. The absorbent material thereby prevents the liquid from causing detrimental effects to the monitoring and calibration equipment used in conjunction with the cassette. The scope includes additional embodiments wherein the inventive concept is applied to other fluid-handling medical devices that require venting of gases.

Abstract: A tube clamping system includes a Bowden cable with an inner member and an outer casing. A first jaw element has a first tube abutment surface, a passage, and a first sliding latch portion. The inner member passes through the passage. A second jaw element has a second tube abutment surface, a cable guide, and a second sliding latch portion. The inner member has a first end held in the mated sliding latch portions so that sliding of the inner member results in selectably positioning the first and second tube abutment surfaces together or spaced apart. An actuator coupled to a second end of the outer casing and a second end of the inner member applies a force to slide the inner member within the outer casing, the passage, and the cable guide. The Bowden cable substantially isolates the tube being clamped from the weight of the actuator.

Abstract: A system for clamping a flexible tube containing medical fluids includes a cable assembly coupled to a remote driver and a slidable clamp that imparts a clamping force to the flexible tube. An electrical continuity detector is included to measure the wear of an internal insulating layer of the cable between a sliding inner wire and a cable casing member. An indication of the wear to the cable is generated in response to a comparison of the electrical integrity of the insulating layer with a threshold. The wear indication enables the cable to be repaired or replaced prior to a malfunction of the overall tube clamp system.

Abstract: A blunt dissector for separating a blood vessel from surrounding tissues in a body comprises a longitudinal rod having a proximal end, a distal end, and an internal passage for conducting insufflation gas between the proximal and distal ends. An interior sleeve is mounted within the longitudinal rod for receiving an endoscope at the proximal end. A transparent tip is mounted to the distal end of the longitudinal rod. A handle is mounted to the proximal end of the longitudinal rod. The longitudinal rod has an outer surface along substantially all of the longitudinal rod between the proximal and distal ends consisting essentially of a fluoropolymer.

Abstract: An air removal device removes air from blood flowing in a perfusion system. A generally cylindrical chamber has a liquid flow region at a lower end thereof and has a gas collection region at an upper end thereof. An arcuate manifold provides an arcuate flow path outside of the chamber having an upstream end and a downstream end. A slit aperture is provided between the arcuate manifold and the chamber along at least a substantial portion of the arcuate manifold. A mixture of gas and liquid introduced into the arcuate flow path at the upstream end flows through the slit aperture to create a spiral flow within the chamber causing the gas to move toward a central axis of the chamber and into the gas collection region.

Abstract: A perfusion system for treating blood during a surgical procedure uses a flow control valve with first and second inlets and first and second outlets. A first intermediate line couples the first outlet to an air removal system. A second intermediate line couples blood from the air removal system to the second inlet. An arterial line carries treated blood from the second outlet back to the patient. The flow control valve has an open position and a recirculate position, wherein the first inlet is coupled to the first outlet when the flow control valve is in either the open position or the recirculate position. The second inlet is coupled to the second outlet and blocked from the first outlet in the open position. The second inlet is coupled to the first outlet and blocked from the second outlet in the recirculate position.

Abstract: A rotary valve unit is provided for blending fluid sources to regulate a temperature of fluid flowing to a heat exchange device in an extracorporeal blood perfusion circuit. A valve body includes a valve chamber having a first inlet port, a second inlet port, a first outlet port, and a second outlet port. A wedged-shaped rotary valve is disposed within the valve chamber and is rotatable within the valve chamber for controlling a blending of the cold fluid entering the fluid chamber from the first inlet port and the return fluid entering the fluid chamber from the second inlet port to regulate the desired temperature of fluid provided to the heat exchanger. The wedge-shaped rotary valve is positionable to provide either only cold fluid to the first outlet port, only return fluid to the first outlet port, or blending of the cold fluid and return fluid to the first outlet port.

Abstract: A venous catheter comprises a flexible plastic tubular body having a center lumen. A plurality of drainage openings are formed in a reinforced opening-containing section of the body. Reinforcement is embedded in the body within the reinforced opening-containing section. The reinforcement includes a series of annular ringlets each formed of a few tightly wound helical turns. The ringlets can be non-interconnected, or interconnected by a helical connecting part by forming the ringlets and connecting parts from a continuous wire. The drainage openings are disposed in spaces formed between successive ringlets.