Abstract: A balloon catheter that includes an elongated main body, a balloon connected to the elongated main body, and a base layer on the outer surface of the balloon. The base layer includes a water-soluble low-molecular weight compound. The balloon catheter also includes a plurality of elongate bodies extending radially away from the outer surface of the balloon. The elongate bodies are crystals of a water-insoluble drug. The elongate bodies each possesses an independent longitudinal axis. At least part of at least some of the elongate bodies are located in the interior of the base layer on the outer surface of the balloon.

Abstract: A balloon catheter that includes an elongated main body extending in an axial direction and a balloon connected to the distal portion of the elongated main body. The balloon includes an interior and is inflatable and deflatable. The balloon catheter also includes a plurality of elongate bodies extending radially away from the outer surface of the balloon. The elongate bodies are crystals of a water-insoluble drug. The elongate bodies each possess an independent longitudinal axis. Each of the elongate bodies includes a base portion at the proximal end of the elongate body. A plurality of elongate body proximal portions extend radially inwardly from the base portion of each of the elongate bodies toward the interior of the balloon. The elongate body proximal portions are continuous extensions of the crystal of the water-insoluble drug.

Abstract: A balloon catheter includes an elongated main body extending in an axial direction and a balloon connected to the elongated main body. The balloon is inflatable and deflatable in the radial direction. The outer surface of the balloon includes a plurality of recesses that are spaced apart from one another. The balloon catheter also includes a plurality of elongate bodies on the outer surface of the balloon. The elongate bodies are crystals of a water-insoluble drug extending in the radial direction of the balloon away from the interior of the balloon. The elongate bodies each possess an independent long axis. At least two elongate bodies of the elongate bodies are positioned in one of the recesses in the outer surface of the balloon. These two elongate bodies extend from within the recess to a surrounding environment in the radial direction of the balloon.

Abstract: A diagnosis assistance device includes a control unit that generates line data indicating an intensity value of a reflected wave from an object, which is present in a transmission direction of ultrasound, for each combination of a movement position of an ultrasound transducer that radially transmits the ultrasound while being moved inside a biological tissue and the transmission direction of the ultrasound with reference to an observation result of a cross section of the biological tissue by the ultrasound transducer and generates a detection image which includes pixels corresponding to the generated line data and in which pixels corresponding to the line data at the same movement position are arranged in one direction. Pixels corresponding to the line data in the same transmission direction are arranged in a direction perpendicular to the one direction, and each pixel value is set according to an abnormality degree of the generated line data.

Abstract: A heat exchanger for an oxygenator device has multiple hollow fiber membranes that each have a hollow portion through which a heat medium passes, wherein the fibers are wound as a cylinder body. Each of the hollow fiber membranes follows a path between opposing ends of the cylinder body which is tilted with respect to a central axis of the cylinder body and is wound around the central axis of the cylinder body, wherein a tilt angle ? with respect to the central axis ranges from 22° to smaller than 67°, and wherein a constituent material of each of the hollow fiber membranes has a Young's modulus E ranging from 2.6 GPa to 0.07 GPa. During winding, the hollow fiber membranes are stretched according to a stretching rate between 0.5% and 3.0% and then fixed at the ends to maintain the stretching.

Abstract: A catheter system includes: a catheter assembly that includes: an inner needle having a needle tip at a distal end thereof, a hollow needle hub fixed to a proximal end section of the inner needle, a catheter shaft into which the inner needle is inserted, and a catheter hub having the inner needle inserted thereinto, wherein the catheter hub is fixed to a proximal end section of the catheter shaft; and a catheter gripper that is attachable to and detachable from the catheter assembly, wherein the catheter gripper includes: a gripping member, and an attaching/detaching mechanism configured to attach and detach a proximal end section of the needle hub to and from a first end section of the gripping member.

Abstract: A lymphangiogenesis inducing device includes: a puncture member including a distal end portion configured to puncture living tissue, and a through hole penetrating the puncture member along a central axis and extending from the distal end portion toward a proximal end; and a rod-shaped body inserted into the through hole and configured to be moved so as to protrude from the distal end portion. The rod-shaped body includes a shaft portion, and a wound imparting structure including at least one protrusion located on the shaft portion and configured to impart a wound to the living tissue.

Abstract: A medical device is disclosed that can help prevent an object existing in a body lumen from clogging a lumen of an elongated member. The medical device including an elongated member having a lumen extending in an axial direction; an insertion member inserted in the lumen of the elongated member on a distal side of the lumen; and a breaking member fixed on an inner surface of the elongated member such that a gap is formed between the insertion member and the breaking member in the lumen of the elongated member on the distal side, and wherein the breaking member exerts a shearing force or a stretching force to the object by rotating relative to the insertion member while the object is between the insertion member and the breaking member.

Abstract: A medical device includes: a substrate layer; an adhesive layer formed on at least a part of the substrate layer and containing a hydrophilic copolymer (1) containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group; and a surface lubricious layer formed on at least a part of the adhesive layer and containing a polymer containing a structural unit derived from acrylamide and a hydrophilic copolymer (2).

Abstract: A medical device includes: a substrate layer; an adhesive layer on at least a part of the substrate layer and containing a hydrophilic copolymer (1) containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group; and a surface lubricious layer formed on at least a part of the adhesive layer and containing a hyaluronic acid or a salt thereof and a hydrophilic copolymer (2).

Abstract: Methods for increasing a proportion of CD56 positive cells in sampled skeletal muscle tissue include soaking the sampled skeletal muscle tissue in a preservation solution.

Abstract: The disclosure provides a medical device that exhibits an excellent lubricating property. The medical device includes: a substrate layer; and a surface lubricious layer formed on at least a part of the substrate layer and containing a hyaluronic acid or a salt thereof and a hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group.

Abstract: medical device that exhibits an excellent lubricating property includes: a substrate layer; and a surface lubricious layer formed on at least a part of the substrate layer, with the surface lubricious layer containing a polymer containing a structural unit derived from acrylamide, and the surface lubricious layer containing a hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from a group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group.

Abstract: A medical device that exhibits an excellent lubricating property includes: a substrate layer; and a surface lubricious layer formed on at least a part of the substrate layer, and containing a hydroxy group-containing compound selected from a group consisting of a non-volatile alcohol, a partially esterified product thereof, and a partially etherified product thereof, and soluble in water, and a hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from a group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group.

Abstract: A method and device handle having a slide assembly are disclosed for controlling rotational speed of a catheter assembly under various rotational loads. The method includes: driving a catheter assembly at a target rotational speed in a first direction; detecting an actual rotational speed of the catheter assembly in the first direction; comparing the target rotational speed and the actual rotational speed of the catheter assembly in the first direction; and stopping the driving of the catheter assembly in the first direction before a completion of predetermined number of rotations in the first direction when the actual rotational speed decreases a predetermined value over a predetermined time frame.

Abstract: A medical device and methods for hemostasis in a living body are disclosed. The medical device including a base configured to arranged on an upper surface of the tissue in the living body; a plurality of levers, each of the plurality of levers having a needle arranged on a lower surface thereof and configured to puncture the tissue in the living body, and wherein the plurality of lever are configured to be received with a slot or track of the base; and at least one tie, the at least one tie configured to hold together the plurality levers and needles upon compressing the tissue in the living body upon moving the plurality of levers inward in the slot or track of the base.

Abstract: Provided is a catheter that is excellent in visibility of a braid distal end portion inside and outside the body, is excellent in stenosed site crossability and trackability to a tortuous blood vessel, and prevents the braid from spreading out due to the stenosed site penetration. The catheter includes a shaft, the shaft includes an inner layer, an outer layer, and a braid that is disposed between the inner layer and the outer layer and includes a plurality of metal wires being woven together, the braid includes a welding portion at a further proximal side than a distal end of the shaft and in the vicinity of a distal end of the braid, and the shaft includes an radiopaque marker at a position separated from the welding portion, thereby preventing the braid from spreading out due to buckling of the shaft, and improving the blood vessel trackability.

Abstract: A drive device includes: a feed screw configured to rotate about a central axis; and a guided member configured to be guided in an axial direction along the central axis, wherein the guided member includes at least one nut member having a screw portion screwed with the feed screw. In a transverse section orthogonal to the central axis, the screw portion is configured to move in both a first direction toward the central axis and a second direction intersecting the first direction.

Abstract: A control device is disclosed that includes a processor configured to: receive a signal from an imaging core, the imaging core including an optical transceiver and an ultrasound transceiver; determine whether the imaging core is in a state where the ultrasound transceiver can properly execute transmission and reception, based on at least one of the signal from the optical transceiver and the signal from the ultrasound transceiver which are received from the imaging; and control execution of an optical path length adjustment for imaging with the optical transceiver when the ultrasound transceiver can properly execute the transmission and reception.