Abstract: A drug solution administration device includes a drug solution reservoir, a drive unit, a rotation detection unit, and a control unit. The control unit counts the number of rotations of the drive unit from when a rotation sensor value reaches a blockage start threshold value until the rotation sensor value reaches a blockage detection threshold value. Further, the control unit determines that a blockage of a flow path has occurred when the rotation sensor value reaches the blockage detection threshold value, and rotates the drive unit in a direction opposite to a direction in which the drug solution is administered based on the counted number of rotations.

Abstract: A method and apparatus are disclosed for forming a drug coating layer capable of preventing breakage of elongated drug crystals on a surface of a balloon and maintaining the drug crystals in an appropriate shape in order to act on a living body. The method includes supplying a coating solution which contains the water-insoluble drug, a water-soluble additive, an organic solvent, and water to the surface of the balloon and evaporating the organic solvent and the water to form an additive layer containing the water-soluble additive and a protruding crystal having a tip end protruding from the additive layer, cutting a surplus portion protruding from the additive layer of the protruding crystal from a part surrounded by the additive layer and forming the part surrounded by the additive layer as the elongated body, and removing the cut-out surplus portion from the drug coating layer.

Abstract: Disclosed is a method for producing a medical instrument having a lubricating layer (a coating layer) exhibiting excellent durability (particularly, sliding durability). The method for producing a medical instrument is a method for producing a medical instrument having a base layer, and a lubricating layer that is carried on at least a part of the base layer. The method for producing a medical instrument also includes applying, to the base layer, a solution containing a block copolymer having a structural unit (A) derived from a reactive monomer having an epoxy group and a structural unit (B) derived from a hydrophilic monomer, an alkylammonium salt having 8 to 24 carbon atoms, and a solvent; and washing off the solution applied to the base layer.

Abstract: A treatment method is disclosed capable of reducing the burden on a patient and enhancing the effect of killing tumor cells. A treatment method for killing a tumor cell, the method including inserting a catheter into a main artery of an organ having the tumor cell, administering an antibody-photosensitive substance into a vein before the inserting of the catheter, inserting an optical fiber into the catheter, reducing an influence of blood in the artery on a near-infrared ray, irradiating at least one of a tumor, the vicinity of the tumor, or a regional lymph node with a first near-infrared ray by the optical fiber, and irradiating an antibody-photosensitive substance bound to a tumor cell membrane in the tumor cell with a second near-infrared ray having a shorter wavelength than that of the first near-infrared ray.

Abstract: Provided is a blood component collection cassette, a blood component collection kit, a blood component collection system, and a flow path internal pressure detection method capable of accurately measuring a circuit internal pressure in negative pressure and positive pressure regions. A flow path (42) formed in a cassette body (40) of a blood component collection cassette (28) has a first line (42a) through which blood flows when a blood component separation device is in operation, and a second line (42b) through which blood does not flow when the blood component separation device is in operation. A first line forming member (54) is provided with a first pressure-receiving portion (60) pressed by a first load detector (88) attached to the blood component separation device. A second line forming member (56) is provided with a second pressure-receiving portion (62) pressed by a second load detector (90) attached to the blood component separation device.

Abstract: A flow path is formed in a cassette body of a blood component collection cassette. The cassette body includes a bulging structure in which at least a portion of the flow path is formed. A first gripped member, which is configured to be gripped by a first gripping member provided on a centrifugal separation device, is disposed on one surface of the bulging structure in a thickness direction thereof. A second gripped member, which is configured to be gripped by a second gripping member to which a load detection unit that is provided on the centrifugal separation device is fixed, is disposed on another surface of the bulging structure in the thickness direction thereof.

Abstract: A line-compression patch and method are disclosed configured to achieve hemostasis in a living body. The line-compression patch includes a line-compression feature extruding out towards a patient contact surface; a base providing the support to the line-compression feature; and a patch feature that provides stability to the line-compression patch by adhering to the patient contact surface.

Abstract: An introducer sheath and method are disclosed capable of reducing a physical burden on a patient by shortening a time necessary for hemostasis at an introduction part after removing the introducer sheath percutaneously introduced into a body lumen. The method of indwelling an introducer sheath in a body lumen includes: puncturing a body lumen in which an introducer sheath needs to be indwelled; and introducing an introducer sheath into a puncture site of the body lumen, the introducer sheath including a catheter main body having a portion provided with a thrombus inducing material and a hub, which is connected to a proximal side of the catheter main body, and wherein the catheter main body is indwelled in the body lumen while a part of the portion provided with the thrombus inducing material is inserted into the body lumen through the puncture site.

Abstract: A medical connector includes: a housing including a male connector connection portion comprising a male connector connection port having a cylindrical shape, a medical instrument connection portion, and a valve body housing portion; and a valve body configured to open and close the male connector connection port, the valve body including a head portion, and a barrel portion that connects to the head portion. When a male connector is inserted into the male connector connection port, the head portion moves from the male connector connection port into the valve body housing portion and a slit in the head portion opens, such that a flow passage from the male connector connection portion to the medical instrument connection portion is formed.

Abstract: An injection needle assembly includes: a needle tube; a needle hub holding the needle tube; a protector movable between a first position at which a needle tip of the needle tube is covered and a second position at which the needle tip of the needle tube is exposed; a biasing member configured to bias the protector toward the needle tip of the needle tube along an axial direction; a retaining member that supports the protector such that the protector is movable along the axial direction, wherein an abutment piece of the protector abuts on the retaining member when the protector is moved to the first position; and a restriction mechanism configured such that, after the protector has moved from the first position to the second position and back to the first position, the restriction mechanism restricts the protector from moving from the first position to the second position again.

Abstract: A treatment method is disclosed, which is capable of causing a medical elongated body to indwell the inside of a palmar artery of a patient, while suppressing kink, poor torque transmission ability, and poor operability of the medical elongated body. The treatment method includes causing a sheath tube of an introducer introduced into a blood vessel via a puncture site formed on an ulnar artery side of a palmar artery of the patient, to indwell the puncture site.

Abstract: A calculus removing device includes a retaining portion (e.g., a wire or gel), a cylinder, an introduction tube, and a hand-operated unit. The retaining portion is configured to retain calculi and broken calculus pieces. The cylinder includes a storage portion configured to store the calculi, an opening communicating with the storage portion, and an introducing portion configured to permit the retaining portion to be introduced into the storage portion. The introduction tube is provided with a lumen which allows introduction of the retaining portion into the storage portion via the introducing portion. The hand operating unit is provided with an operating member configured to operate the introduction of the retaining portion into the storage portion.

Abstract: A plunger for a syringe that includes a barrel includes: a gasket mounting portion located at a distal end of the plunger; a disk positioned at a proximal end of the gasket mounting portion; a shaft extending proximally from the disk, wherein the shaft comprises a plurality of slats extending proximally from the disk; a pressing portion located at a lower end of the shaft; and a plunger inclination-prevention unit that is located at a distal end of the shaft and is configured to inhibit the plunger from inclining inside the barrel of the syringe. The plunger inclination-prevention unit comprises one or more axially inclined plates, each having a first end disposed on the disk, extending obliquely proximal with respect to a central axis of the shaft, and having a second end disposed on one of the slats.

Abstract: A drug coating layer that prevents breakage of elongated drug crystals on a balloon surface while maintaining the drug crystals in an appropriate shape to act on the living body includes plural elongated bodies which are crystals of a water-insoluble drug each extending from the surface of the balloon at various lengths and angles, and a water-soluble additive layer provided in a space between an outer surface of an aggregate of the elongated bodies and the balloon surface to fill a space between the elongated bodies. The outer surface of the additive layer being located outside the aggregate, being uneven connecting a plurality of tip ends and side surfaces of the elongated bodies to each other. The tip ends of the elongated bodies slightly protrude from the additive layer, and the side surfaces and/or tip surfaces of the elongated body are exposed on the surface of the additive layer.

Abstract: Provided are a bearing and a medical device in which a gap is secured between an inner ring and an outer ring, and the gap can be used as a flow path for a fluid or an object. A bearing having a plurality of rolling elements between an inner ring and an outer ring is provided with a raceway surface on which the rolling elements roll on the outer ring and receiving portions for rotatably accommodating the rolling elements at a position of the inner ring facing the raceway surface.

Abstract: A hemostatic device includes a flexible band adapted to be wrapped around a patient's limb at a site on the limb where bleeding is to be stopped, a portion for securing the band in a wrapped state to the limb, a curved plate which is made of a material more rigid than the band and at least a portion of which is curved toward the inner peripheral side thereof, a main balloon which is provided on the inner peripheral side of the curved plate and which inflates when a fluid is introduced therein, and a pressing member which is provided between the curved plate and the main balloon so that at least a portion thereof overlaps with the balloon and which is adapted for pressing against the balloon. The device provides an excellent hemostatic effect and prevents numbness and poor circulation in areas peripheral to the site of attachment.

Abstract: A medical puncture needle includes a rod-shaped main body portion; and a blade surface formed at a distal end portion of the main body portion. The blade surface includes a first blade surface portion and a second blade surface portion that intersect to form a blade edge. A needle tip is formed at a location at which a distal end of the blade edge intersects a first ridge line at an outer edge of the first blade surface and a second ridge line at an outer edge of the second blade surface. At least one of the blade surface portions is planar, and, in a central axis direction of the main body portion, said at least one blade surface portion extends to a location proximal of a middle position of a blade surface region in which the blade surface is formed.

Abstract: A medical device includes a connector portion. The connector portion includes an inner cylinder connectable to another medical device having an elastic valve, a valve body against which the elastic valve is pressed from a distal end side due to connection of the inner cylinder and another medical device, and an outer cylinder disposed radially outside the inner cylinder, and the connector portion is configured to provide fluid communication between the connector portion and another medical device by moving the inner cylinder in an axial direction with respect to the outer cylinder in a state where the inner cylinder is connected with another medical device. The connector portion further includes an anchor that suppresses movement of the valve body with respect to the inner cylinder toward a proximal end.

Abstract: A hemostatic device includes a flexible band adapted to be wrapped around a patient's limb at a site on the limb where bleeding is to be stopped, a portion for securing the band in a wrapped state to the limb, a curved plate which is made of a material more rigid than the band and at least a portion of which is curved toward the inner peripheral side thereof, a main balloon which is provided on the inner peripheral side of the curved plate and which inflates when a fluid is introduced therein, and a pressing member which is provided between the curved plate and the main balloon so that at least a portion thereof overlaps with the balloon and which is adapted for pressing against the balloon. The device provides an excellent hemostatic effect and prevents numbness and poor circulation in areas peripheral to the site of attachment.

Abstract: A puncture apparatus includes: a needle member having a tubular shape and comprising a flexible portion that is deformable; and a puncture assisting member that is movable or deformable in an axial direction of the needle member between: a restricting position in which the puncture assisting member is located outside the flexible portion of the needle member in a radial direction of the needle member, and thereby restricts deformation of the flexible portion, and a permissive position in which the puncture assisting member is not located outside the flexible portion in the radial direction, and thereby permits deformation of the flexible portion. The puncture assisting member is configured to move or deform from the restricting position to the permissive position in conjunction with an operation of inserting the flexible portion into a living body at a time of puncturing the living body with the needle member.