Abstract: A lymphangiogenesis inducing device includes: an outer needle including a needle point insertable into a subcutaneous tissue, and a through-hole extending in an axial direction and penetrating the outer needle; and an inner needle inserted into the through-hole. The inner needle includes a cavity portion extending along the axial direction, and a wound imparting structure that is formed in a part of a distal end configured to protrude past the needle point of the outer needle and configured to cause a wound on the subcutaneous tissue. The wound imparting structure includes one or more protrusions protruding outward from the inner needle.

Abstract: A method of forming a wound for inducing lymphangiogenesis includes: providing a lymphangiogenesis inducing device that includes: a puncture member including a distal end portion configured to puncture living tissue, and a through hole penetrating the puncture member along a central axis and extending from the distal end portion toward a proximal end, and a rod-shaped body inserted into the through hole and configured to be moved so as to protrude from the distal end portion, where the rod-shaped body includes a shaft portion, and a wound imparting structure; puncturing the living tissue with the lymphangiogenesis inducing device while the rod-shaped body is located in the through hole; passing the lymphangiogenesis inducing device through a regeneration route; pulling back the puncture member while the rod-shaped body is left in the living tissue; and pulling back the rod-shaped body.

Abstract: A catheter includes an outward protruding portion provided at a distalmost end portion and protruding outward in a radial direction; and an inward protruding portion provided at the distalmost end portion and protruding inward in the radial direction.

Abstract: An elongated medical body having a resistance that is constantly 10 gf or less when a tube is moved 100 times while the elongated medical body is clamped at 500 gf between a pair of abutting members.

Abstract: A guide wire for guiding a dilator to be inserted into a living body includes: a flexible elongated shaft portion; a puncture portion at a distal end portion of the shaft portion to form a hole in biological tissue; and an elastically deformable cover portion covering the puncture portion. The cover portion includes a sparse pitch portion that has a wire member wound in a spiral shape and axially contractible, and a distal end cover located on a distal end side of the sparse pitch portion and covering at least a part of the puncture portion. The puncture portion includes a first contact portion. The distal end cover includes a second contact portion configured to contact the first contact portion from a proximal end side, so that relative axial movement of the first and second contact portions is restricted by the first contact portion contacting the second contact portion.

Abstract: A method for producing a cell culture containing desired cells is provided. The desired cells are induced to be differentiated from pluripotent stem cells. The method includes seeding a cell population by dispersing embryoid bodies obtained by inducing differentiation from the pluripotent stem cells to the desired cells. The embryoid bodies are dispersed at a density reaching confluence or higher.

Abstract: A medical connector includes: a first connection member having a first connection port, and a second connection port that fluidically communicates with the first connection port; a second connection member; and a ratchet mechanism portion that couples the first connection member and the second connection member.

Abstract: An image processing device includes a drive unit connected with an ultrasound element or an image sensor element, and an image processing unit that sequentially generates two-dimensional images of an organ, a blood vessel, or a medical instrument, based on information which is acquired by the ultrasound element or the image sensor element, and that generates a three-dimensional image based on the two-dimensional image. The image processing unit includes a storage unit that stores position correspondence information and/or image correspondence information, and a control unit that determines a position inside the three-dimensional image corresponding to a current position of the ultrasound element or the image sensor element, based on the position correspondence information or the image correspondence information, and that generates display information in real time, in which the determined position inside the three-dimensional image is identified and displayed inside the three-dimensional image.

Abstract: A control device configured to control a pressurization and decompression operation of a pump configured to inflate and deflate a balloon by pressurizing and decompressing the balloon attached to a distal portion of a catheter through the catheter inserted into a luminal organ of a patient includes a control unit configured to acquire image data obtained by imaging the luminal organ at least while the pump is caused to perform a pressurization operation, determine whether air bubbles are mixed in an expansion medium injected into the balloon in the pressurization operation with reference to the acquired image data, and when it is determined that the air bubbles are mixed, cause the pump to perform a decompression operation before a preset decompression timing.

Abstract: An indeflation system includes a control unit configured to control an operation of a pump configured to pressurize or depressurize an inside of a catheter at a distal portion of which a balloon is provided, in which the control unit acquires a medical image of the balloon provided at the distal portion of the catheter inserted into a lumen, the balloon pressurized by the pump, detects presence or absence of an abnormality of the balloon on the basis of the medical image of the pressurized balloon, and controls the pump so as to depressurize the balloon in a case where the abnormality of the balloon is detected.

Abstract: The present application discloses various methods of constructing hemostasis devices with folded balloon assemblies.

Abstract: An oxygen measurement device constituting an oxygen measurement system includes a urethral catheter and an oxygen sensor main body. The urethral catheter has a shaft in which a urethral catheter lumen that enables circulation of urine flowed in via a urethral catheter port from inside a bladder is formed; and has a hub in which a urine lumen that is provided at a proximal end of the shaft and communicates with the urethral catheter lumen is formed. The oxygen sensor main body is provided on the hub in a manner capable of being brought into contact with urine circulating in the urine lumen, and detects oxygen in the urine.

Abstract: A medical device is disclosed that can help prevent an object existing in a body lumen from clogging a lumen of an elongated member. The medical device including an elongated member having a lumen extending in an axial direction; an insertion member inserted in the lumen of the elongated member on a distal side of the lumen; and a breaking member fixed on an inner surface of the elongated member such that a gap is formed between the insertion member and the breaking member in the lumen of the elongated member on the distal side, and wherein the breaking member exerts a shearing force or a stretching force to the object by rotating relative to the insertion member while the object is between the insertion member and the breaking member.

Abstract: A medical device having a function of promoting fusion between living body organs, which includes a sheet-like main body portion configured to promote fusion of anastomosis portions, a cylindrical portion that is disposed on a center portion side in a plane direction of the main body portion with respect to an outer peripheral portion in the plane direction of the main body portion, protrudes in a first direction intersecting the plane direction of the main body portion, and has a lumen, and a connection portion that connects the main body portion and the cylindrical portion, and the medical device 100 is configured so that a relationship among hardness of the cylindrical portion, hardness of the connection portion, and hardness of the main body portion satisfies the following expression (1): hardness of cylindrical portion >hardness of connection portion >hardness of main body portion (1).

Abstract: A medical elongated body including a shaft portion comprising a linear body and a proximal portion; a distal member disposed in a distal side of the shaft portion and having a distal end and a proximal end, the distal member having a first region having an inner layer and an outer layer which are made of a resin material, and a second region having the inner layer and the outer layer, and a tubular member made of a metallic material and disposed between the inner layer and the outer layer in the second region, the proximal end opening portion comprising an inclined region having a proximally-decreasing dimension; and a reinforcement layer comprising a metallic material arranged between the inner layer and the outer layer from the first region to the second region of the distal member.

Abstract: A medical device is disclosed for grinding substance inside a body lumen. The medical device includes a rotatable tubular drive shaft; a treatment member connected to the drive shaft so that rotation of the drive shaft results in rotation of the treatment member; an outer sheath configured to house the drive shaft; a handle located at a proximal portion of the drive shaft and at a proximal portion of the outer sheath; a guide wire lumen tube disposed within the tubular drive shaft and the treatment member, the guide wire lumen tube having a guide wire lumen; a distal end of the guide wire lumen tube located at a distal end of the treatment member or distal to the distal end of the treatment member; and a proximal portion of the guide wire lumen tube configured to penetrate a wall of the handle.

Abstract: A medical device includes: a substrate layer; an adhesive layer on at least a part of the substrate layer and containing a hydrophilic copolymer (1) containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group; and a surface lubricious layer formed on at least a part of the adhesive layer and containing a hyaluronic acid or a salt thereof and a hydrophilic copolymer (2).