Abstract: A vascular closure device assembly, comprises a sheath comprising: a sheath main body defining a channel therethrough, a sheath engagement portion, and a sheath mounting portion located at a proximal end of the sheath main body. The assembly comprises a housing within which the sheath mounting portion is secured such that the sheath is rotatable relative to the housing, and such that the housing inhibits axial displacement of the sheath relative to the housing. The assembly also includes a dilator comprising a dilator main body, and a dilator engagement portion extending from the dilator main body towards the sheath. The dilator engagement portion is configured to engage the sheath engagement portion such that axial displacement of the dilator relative to the sheath causes the sheath to rotate relative to the housing, and wherein the housing is configured to inhibit axial displacement of the sheath during rotation.

Abstract: A knot delivery device for securing a suture comprises an elongated body having a proximal end and a distal end, a pre-configured knot disposed at the distal end of the elongated body, a suture snare having a snare configured to capture suture material, wherein the snare extends through the pre-configured knot and a suture locker secured to one end of material forming the pre-configured knot, wherein tension applied to the suture locker tightens the pre-configured knot.

Abstract: The present application discloses devices and methods for performing a vascular closure procedure that comprises inserting a sheath into a tissue tract defined in a body part, temporarily sealing a vascular access site, flushing the tissue tract with a flushing fluid via the sheath, dispensing a procoagulant material into the tissue tract adjacent the vascular access site via the sheath, and then unsealing the vascular access site to cause coagulation of blood adjacent the vascular access site.

Abstract: The present application discloses a device and methods for performing a vascular closure procedure that comprises inserting a sheath into a tissue tract defined in a body part and injecting a procoagulant material into the tissue tract adjacent a vascular access site via the sheath.

Abstract: The present application discloses devices and methods for monitoring the performance of a hemostasis device during a hemostatic procedure.

Abstract: The present invention relates to a dilator. The dilator includes a shaft, a lumen and a hub. The shaft has at least two stiffness sections with the stiffness sections becoming less rigid as they approach a distal end of the shaft. The varying stiffness sections allow the dilator to track along the guidewire through torturous vasculature so as the dilator is advanced and the stiffness is changed, the stiffer sheath can advance smoothly through a blood vessel. The dilator may also taper at the distal tip to stretch the initial skin puncture hole larger to accommodate the dilator shaft and ease the sheath tip insertion through to the vasculature. Or the shaft may taper from where it extends beyond the sheath distal tip to the distal end so that it can reach further distal in the vasculature. The dilator may also include an atraumatic tip for easier advancement of the dilator. The dilator distal end may also include one or more radiopaque markers and a shaped distal end.

Abstract: A system for performing vascular hemostasis comprises a balloon insertable into a tissue track so as to be disposed outside a vessel above an opening formed in the vessel. A hemostasis layer is removably disposed on at least a portion of an outer surface of the balloon. A balloon tube is fluidly coupled to the balloon and configured to selectively inflate or deflate the balloon. The balloon is inflatable above the opening such that the hemostasis layer is disposed on the outer surface of the vessel and closes the opening. The hemostasis layer is separable from the balloon so as to remain disposed on the outer surface of the vessel when the balloon is removed from the tissue track, and continues to close the opening after removal of the balloon.

Abstract: A vascular closure device assembly, comprises a sheath comprising: a sheath main body defining a channel therethrough, a sheath engagement portion, and a sheath mounting portion located at a proximal end of the sheath main body. The assembly comprises a housing within which the sheath mounting portion is secured such that the sheath is rotatable relative to the housing, and such that the housing inhibits axial displacement of the sheath relative to the housing. The assembly also includes a dilator comprising a dilator main body, and a dilator engagement portion extending from the dilator main body towards the sheath. The dilator engagement portion is configured to engage the sheath engagement portion such that axial displacement of the dilator relative to the sheath causes the sheath to rotate relative to the housing, and wherein the housing is configured to inhibit axial displacement of the sheath during rotation.

Abstract: The present application discloses a hemostatic device comprising a flexible, adjustable closure device that is adapted to fit the lower leg and foot of patients having a range of anatomical differences in leg and foot shape and size, the hemostatic device further comprising at least one compression element that is adapted to apply targeted pressure to a surgical vascular access site located on the patient's lower leg or foot. In some embodiments, the compression element is moveable such that it may be used to apply pressure to a select one of common arterial access points located on the lower leg or foot.

Abstract: The present application discloses medical instruments that utilize self-healing polymers as all or portion of the valves and valve assemblies thereof, such that these valves can self-heal while or after being punctured by an ancillary device during a surgical procedure and thereby help minimize blood loss and achieve hemostasis.

Abstract: Excess suture material may be trimmed after knot tying using a device having an elongated shaft, an elongated tubular cutter disposed over the shaft and an elongated tubular barrel disposed over the cutter. A suture loader at a distal end of the shaft that engages suture material may be opened and closed by a first actuator that causes relative motion between the shaft and the barrel. A second actuator may cause relative motion between the cutter and both of the barrel and the shaft to sever suture material engaged by the closed suture loader.

Abstract: The present application discloses a device and methods for performing a vascular closure procedure that comprises inserting a sheath into a tissue tract defined in a body part and injecting a procoagulant material into the tissue tract adjacent a vascular access site via the sheath.

Abstract: The present application discloses devices and methods for performing a vascular closure procedure that comprises inserting a sheath into a tissue tract defined in a body part, temporarily sealing a vascular access site, flushing the tissue tract with a flushing fluid via the sheath, dispensing a procoagulant material into the tissue tract adjacent the vascular access site via the sheath, and then unsealing the vascular access site to cause coagulation of blood adjacent the vascular access site.

Abstract: The present application discloses various embodiments of a hemostasis device in the form of a kit having a compression element and a plurality of adjustable straps that permit for a customized fit of the hemostasis device on varied anatomy.

Abstract: An elongated deployment shaft carrying a needle deployment assembly with needles carrying sutures and a stabilizer. A catcher tube over the shaft having a catcher assembly at a distal end may retain a portion of the needles when passed through the tissue into engagement with catcher assembly. The catcher and needle deployment assemblies are configured to asynchronously engage the plurality of needles when moved distally beyond the catcher assembly. A sheath over the catcher tube may sandwich the tissue against the stabilizer when expanded. A first actuator may move catcher tube distally to decrease distance between proximal and distal ends of the stabilizer expand it and may move the sheath distally to sandwich the tissue. A second actuator may deflect the needles outward to move proximally through the tissue and engage the catcher and return a portion of each not retained by the catcher to a distal position.

Abstract: The present application discloses medical instruments that utilize self-healing polymers as all or portion of the valves and valve assemblies thereof, such that these valves can self-heal while or after being punctured by an ancillary device during a surgical procedure and thereby help minimize blood loss and achieve hemostasis.

Abstract: A knot may be formed in suture material using a device having an elongated body with a longitudinal axis and a holder. A rail portion of the suture material is secured with a first grasper on the elongated body and a non-rail portion of the suture material is secured with a second grasper on the holder. A plurality of helical windings may be created with the non-rail portion. Detaching the holder from the elongated body in a motion away from the longitudinal axis of the elongated body completes the knot. The holder may be wrapped around the elongated body in a knot-forming pattern.

Abstract: The present application discloses a hemostatic device comprising a flexible, adjustable closure device that is adapted to fit the lower leg and foot of patients having a range of anatomical differences in leg and foot shape and size, the hemostatic device further comprising at least one compression element that is adapted to apply targeted pressure to a surgical vascular access site located on the patient's lower leg or foot. In some embodiments, the compression element is moveable such that it may be used to apply pressure to a select one of common arterial access points located on the lower leg or foot.

Abstract: Systems and methods are provided for percutaneously suturing tissue. An elongated deployment member having a guide member coaxially disposed over a shaft member may be used to carry a needle deployment member. The needle deployment member may be carried at a distal end of the elongated deployment member and include a plurality of needles releasably secured to the needle deployment member, wherein each needle is routed coaxially within the distal end of the needle deployment member. The needle deployment member may further include a needle pusher driven by a link coaxially disposed within the shaft member, wherein the needle pusher is configured to advance each needle through the distal end of the needle deployment member and coaxially over the proximal end of the needle deployment member to position the plurality of needles at a piercing angle in a proximal direction.