Abstract: Methods for treating a CD30-positive cancer in a subject are disclosed, wherein the methods comprise administering a lymphodepleting chemotherapy and CD30-specific chimeric antigen receptor (CAR)-expressing cells.
Type:
Application
Filed:
June 4, 2021
Publication date:
August 24, 2023
Applicants:
Tessa Therapeutics Ltd., The University of North Carolina at Chapel Hill
Inventors:
Aung Myo, Ivan David Horak, Jonathan Serody, Gianpietro Dotti, Barbara Savoldo
Abstract: The invention relates to the expansion of T cells and particularly, although not exclusively, to the expansion of gamma delta T cells, and the optimization of medium, serum and cytokine combinations for large-scale ex vivo expansion of gamma delta T cells for clinical use.
Type:
Application
Filed:
September 26, 2017
Publication date:
June 4, 2020
Applicants:
Tessa Therapeutics Ltd., Singapore Health Services Pte. Ltd.
Inventors:
Cheryl Lai-Lai CHIANG, Who-Whong WANG, Han Chong TOH