Abstract: The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.
Type:
Grant
Filed:
May 27, 2010
Date of Patent:
April 9, 2013
Assignee:
TetraLogic Pharmaceuticals Corp.
Inventors:
Stephen M. Condon, Yijun Deng, Matthew D. Alexander, Matthew G. Laporte
Abstract: The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.
Type:
Application
Filed:
May 27, 2010
Publication date:
May 31, 2012
Applicant:
TETRALOGIC PHARMACEUTICALS CORP.
Inventors:
Stephen M. Condon, Yijun Deng, Matthew D. Alexander, Matthew G. Laporte
Abstract: The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy.
Type:
Application
Filed:
May 25, 2010
Publication date:
April 19, 2012
Applicant:
TETRALOGIC PHARMACEUTICALS CORP
Inventors:
Stephen M. Condon, Yijun Deng, Matthew D. Alexander, Matthew G. Laporte
Abstract: TNF? gene expression can be used as a biomarker of a cell's sensitivity to antagonists of inhibitor of apoptosis proteins (IAPs). Methods of the invention are useful for screening patients to identify those who could benefit from administration of an IAP antagonist to treat various malignant or benign tumors, benign proliferative diseases, or autoimmune diseases.
Type:
Application
Filed:
May 7, 2008
Publication date:
January 13, 2011
Applicant:
TETRALOGIC PHARMACEUTICALS CORP.
Inventors:
Alireza Alavi, Mark A. McKinlay, Srinivas K. Chunduru, John Silke, David Vaux, James Vince