Abstract: Disclosed are humanized antibodies that bind specifically to TNF superfamily member 15 (TNFSF15), also known as TL1A. Methods of making and using the anti-TL1A antibodies are also described. The humanized antibodies may be antagonists and may used to treat or diagnose conditions associated with TL1A function.
Type:
Grant
Filed:
April 3, 2014
Date of Patent:
August 16, 2016
Assignee:
TEVA BIOPHARMACEUTICALS USA, INC.
Inventors:
Rodger Smith, Palanisamy Kanakaraj, Viktor Roschke, Craig Rosen, Bridget A. Cooksey
Abstract: Disclosed are humanized antibodies that bind specifically to TNF superfamily member 15 (TNFSF15), also known as TL1A. Methods of making and using the anti-TL1A antibodies are also described. The humanized antibodies may be antagonists and may used to treat or diagnose conditions associated with TL1A function.
Type:
Application
Filed:
April 3, 2014
Publication date:
October 23, 2014
Applicant:
TEVA Biopharmaceuticals USA, Inc.
Inventors:
Rodger SMITH, Palanisamy Kanakaraj, Viktor Roschke, Craig Rosen, Bridget A. Cooksey
Abstract: Disclosed are humanized antibodies that bind specifically to TNF superfamily member 15 (TNFSF15), also known as TL1A. Methods of making and using the anti-TL1A antibodies are also described. The humanized antibodies may be antagonists and may used to treat or diagnose conditions associated with TL1A function.
Type:
Grant
Filed:
August 14, 2012
Date of Patent:
May 20, 2014
Assignee:
TEVA Biopharmaceuticals USA, Inc.
Inventors:
Rodger Smith, Palanisamy Kanakaraj, Viktor Roschke, Craig Rosen, Bridget A. Cooksey
Abstract: The present invention is directed to antigen-binding polypeptides, or variants or derivatives thereof which specifically bind the LIGHT polypeptide. The invention is also directed to methods of making and using such antibodies specifically in the treatment or diagnosis of immune, inflammatory and malignant diseases or conditions (e.g. inflammatory bowel disease; Crohn's disease, ulcerative colitis, multiple sclerosis, rheumatoid arthritis and transplantation).
Type:
Application
Filed:
August 8, 2013
Publication date:
December 5, 2013
Applicant:
TEVA Biopharmaceuticals USA, Inc.
Inventors:
Rodger Smith, Palanisamy Kanakaraj, Bridget A. Cooksey, Viktor Roschke, Craig Rosen
Abstract: Disclosed are humanized antibodies that bind specifically to the receptor CXCR3. The humanized antibodies may be antagonists and may be used to treat or diagnose conditions associated with CXCR3 function.
Abstract: The present invention is directed to antigen-binding polypeptides, or variants or derivatives thereof which specifically bind the LIGHT polypeptide. The invention is also directed to methods of making and using such antibodies specifically in the treatment or diagnosis of immune, inflammatory and malignant diseases or conditions (e.g. inflammatory bowel disease; Crohn's disease, ulcerative colitis, multiple sclerosis, rheumatoid arthritis and transplantation).
Type:
Grant
Filed:
March 22, 2010
Date of Patent:
September 3, 2013
Assignee:
Teva Biopharmaceuticals USA, Inc.
Inventors:
Rodger Smith, Palanisamy Kanakaraj, Bridget A. Cooksey, Viktor Roschke, Craig Rosen
Abstract: Disclosed are humanized antibodies that bind specifically to the receptor CXCR3. The humanized antibodies may be antagonists and may be used to treat or diagnose conditions associated with CXCR3 function.
Type:
Grant
Filed:
January 29, 2008
Date of Patent:
May 7, 2013
Assignee:
Teva Biopharmaceuticals USA, Inc.
Inventors:
Rodger Smith, Palanisamy Kanakaraj, Viktor Roschke
Abstract: Disclosed are humanized antibodies that bind specifically to the receptor TNF superfamily member 15 (TNFSF15), also known as TL1A. Methods of making and using the anti-TL1A antibodies are also described. The humanized antibodies may be antagonists and may used to treat or diagnose conditions associated with TL1A function.
Type:
Grant
Filed:
November 13, 2008
Date of Patent:
September 11, 2012
Assignee:
Teva Biopharmaceuticals USA, Inc.
Inventors:
Rodger Smith, Palanisamy Kanakaraj, Viktor Roschke, Craig Rosen, Bridget A. Cooksey