Patents Assigned to Texas A&M University Systems
  • Patent number: 11523998
    Abstract: Pharmaceutical or nutraceutical formulations are provided for treating inflammation in a subject in need thereof, as well as methods of treating inflammation in a subject in need thereof by administering one of the formulations. In some aspects, the pharmaceutical or nutraceutical formulation includes an effective amount of (i) palmitoylethanolamide or a derivative thereof, and (ii) one, two, three or more different small-molecule polyphenols or derivatives thereof to alleviate one or more causes or symptoms of the inflammation in the subject. In some aspects, the formulations include all three, e.g. the formulations includes (i) palmitoylethanolamide or a derivative thereof, (ii) quercetin or a derivative thereof, and (iii) curcumin or a derivative thereof. In some instances, the components (i)-(iii) discussed above are present at a mass ratio of about (i) 4 mg to 6 mg of palmitoylethanolamide or a derivative thereof to (ii) about 0.5 to 2.5 mg curcumin or a derivative thereof, and (iii) about 0.5 mg to 1.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: December 13, 2022
    Assignees: The Texas A&M University System, Core Vibe Health Inc.
    Inventors: Susanne U. Mertens-Talcott, Ariela Betsy Thomas, Vinicius De Paula Venancio, Geoffrey R. Pfeifer, Blake M. Ebersole
  • Patent number: 11518903
    Abstract: A method of applying a gas-impermeable coating includes forming a polyelectrolyte complex suspension. The polyelectrolyte complex suspension is applied to a substrate. The substrate having the polyelectrolyte complex applied thereon is treated. The treating reduces salt content of the polyelectrolyte complex. The treating results in a gas-impermeable coating being formed on the substrate.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: December 6, 2022
    Assignee: The Texas A & M University System
    Inventors: Jaime C. Grunlan, Merid Haile, Ryan Smith
  • Patent number: 11519011
    Abstract: The present invention provides methods and compositions for increasing lignin degradation to produce a biological product. Also provided are methods for increasing expression of laccase in a bacterial species to produce increased lignin degradation. Also provided are bacterial cells and commodities or commodity produces produced from such methods.
    Type: Grant
    Filed: March 28, 2016
    Date of Patent: December 6, 2022
    Assignee: The Texas A&M University System
    Inventors: Shuhua Yuan, Shangxian Xie, Xin Wang
  • Patent number: 11516976
    Abstract: Disclosed are various embodiments for reinforcement learning-based irrigation control to maintain or increase a crop yield or reduce water use. A computing device may be configured to determine an optimal irrigation schedule for a crop planted in a field by applying reinforcement learning (RL), where, for a given state of a total soil moisture, the computing device performs an action, the action comprising waiting or irrigating crop. An immediate reward may be assigned to a state-action pair, the state-action pair comprising the given state of the total soil moisture and the action performed. The computing device may instruct an irrigation system to apply irrigation to at least one crop in accordance with the optimal irrigation schedule determined, where the optimal irrigation schedule includes an amount of water to be applied at a predetermined time.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: December 6, 2022
    Assignee: The Texas A&M University System
    Inventors: Lijia Sun, Jiang Hu, Dana O. Porter, Thomas H. Marek, Charles C. Hillyer, Yanxiang Yang
  • Patent number: 11493085
    Abstract: A hybrid bearing assembly includes a bushing. A sleeve is rotationally disposed within the bushing and a support layer is disposed around an outer perimeter of the bushing. A protective sleeve is disposed abutting the sleeve. A protective bushing is disposed abutting the bushing.
    Type: Grant
    Filed: May 26, 2020
    Date of Patent: November 8, 2022
    Assignee: The Texas A&M University System
    Inventors: Abhay R. Patil, Robert B. Hure, Adolfo Delgado Marquez, Burak C. Ayyildiz, Wenjie Yin
  • Publication number: 20220349077
    Abstract: Provided herein is an electrodialysis metathesis system that has at least one stack or quad of compartments arranged so each compartment is in fluid communication with its adjacent compartment via alternating cation—and anion-exchange membranes. The compartments in a stack are a feed compartment, a substitution salt solution compartment, a first concentrated compartment and a second concentrated compartment. Also provided are processes and methods for separating or recovering a metal, for example, a rare earth element, or a salt or a combination thereof from a salt-containing water. Simultaneous metathesis reactions and electrodialysis across the stack recovers one or more metal or salts from the salt-containing water which desalinates the salt-containing water.
    Type: Application
    Filed: July 19, 2022
    Publication date: November 3, 2022
    Applicant: Texas A&M University System
    Inventors: Lucy Mar Camacho Chico, Mohammad U. Shafiq
  • Patent number: 11479355
    Abstract: A flapping-wing aircraft includes a support frame, a motor coupled to the support frame, a pair of wings coupled to the support frame, and a linkage assembly coupled to the support frame and configured to translate an output torque of the motor into flapping motion of the wings, wherein the linkage assembly includes a first link coupled to a rotational output of the motor, a second link pivotably coupled to the first link at a first pivot joint, a third link pivotably coupled to the second link at a second pivot joint, and a fourth link pivotably coupled to the support frame and slidably coupled to the third link, and wherein the fourth link is coupled to a first wing of the pair of wings.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: October 25, 2022
    Assignee: The Texas A&M University System
    Inventors: Moble Benedict, David A. Coleman
  • Publication number: 20220332703
    Abstract: NR4A1 ligands, pharmaceutical compositions including the NR4A1 ligands, and related methods of use are described. Methods of treating a disease or condition in an individual treatable by modulation of NR4A1 activity, comprising administering to the individual a therapeutically effective amount of a compound or a pharmaceutical composition described herein.
    Type: Application
    Filed: October 26, 2021
    Publication date: October 20, 2022
    Applicant: The Texas A&M University System
    Inventor: Stephen SAFE
  • Patent number: 11476786
    Abstract: An electric machine includes a stator having a stator winding disposed thereon. A rotor is electromagnetically exposed to the stator. A field winding and an induction winding are disposed on the rotor. A rectifier is electrically coupled to the induction winding and the field winding. Upon application of a voltage to the stator winding, the stator winding produces a first rotating magnetic field and a second rotating magnetic field that has a different spatial frequency than the first rotating magnetic field. The first rotating magnetic field interacts asynchronously with the induction winding to produce an alternating current in the induction winding. The rectifier changes the alternating current to a direct current that is supplied to the field winding. The field winding interacts synchronously with the second rotating magnetic field.
    Type: Grant
    Filed: April 21, 2021
    Date of Patent: October 18, 2022
    Assignee: The Texas A&M University System
    Inventors: Hamid A. Toliyat, Matthew C. Gardner, Dorsa Talebi
  • Patent number: 11474952
    Abstract: Methods, systems, and computer readable media for performing page fault handling are disclosed. According to one method, the method includes: after a translation lookaside buffer (TLB) miss associated with a virtual memory page occurs, identifying, in a page table, a page table entry (PTE) associated with the virtual memory page; determining, using a first indicator in the PTE, that the virtual memory page is not present in a main memory; determining, using a second indicator in the PTE, that the virtual memory page is associated with a valid memory address and that the virtual memory page is capable of using pre-allocated pages; obtaining, from a pre-allocation table, a page frame number associated with a pre-allocated page; and updating the PTE to indicate the page frame number.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: October 18, 2022
    Assignees: The Texas A&M University System, Hewlett Packard Enterprise Development LP
    Inventors: Narasimha Reddy Annapareddy, Chih-Chieh Chou, Chandrahas Tirumulasetty, Paul Gratz, Ayman Abouelwafa
  • Patent number: 11459439
    Abstract: An embodiment includes a system comprising: a monolithic shape memory polymer (SMP) foam having first and second states; wherein the SMP foam includes: (a) polyurethane, (b) an inner half portion having inner reticulated cells defined by inner struts, (c) an outer half portion, having outer reticulated cells defined by outer struts, surrounding the inner portion in a plane that provides a cross-section of the SMP foam, (d) hydroxyl groups chemically bound to outer surfaces of both the inner and outer struts. Other embodiments are discussed herein.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: October 4, 2022
    Assignees: Lawrence Livermore National Security, LLC, The Texas A&M University System
    Inventors: Landon D. Nash, Duncan J. Maitland, Nicole Docherty, Thomas S. Wilson, Ward Small, IV, Jason Ortega, Pooja Singhal
  • Patent number: 11446371
    Abstract: The present invention provides methods and compositions to reduce binding of fibrinogen to the ClfA in a gram positive bacterial infections using monoclonal antibody, a polyclonal antibody, an antigen-binding antibody fragment or a composition that specifically binds to a portion of ClfA with the sequence of SEQ ID No: 15, SEQ ID NO: 16, SEQ ID NO: 17, and SEQ ID NO: 18.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: September 20, 2022
    Assignee: The Texas A&M University System
    Inventors: Vannakambadi K. Ganesh, Magnus Hook
  • Publication number: 20220294472
    Abstract: A method and system for decoding low density parity check (“LDPC”) codes. An LDPC code decoder includes LDPC decoding circuitry comprising a Q message generator and a P sum adder array. The Q message generator combines an R message from a previous iteration with a P message to produce a Q message. The P sum adder array adds the P message to a difference of an R message from a current iteration and the R message from the previous iteration to produce an updated P message.
    Type: Application
    Filed: May 13, 2022
    Publication date: September 15, 2022
    Applicant: The Texas A&M University System
    Inventors: Kiran Kumar GUNNAM, Gwan S. CHOI
  • Patent number: 11433130
    Abstract: The present disclosure provides a recombinant viral vector comprising at least one transgene inserted into a Marek's disease viral genome for treatment of diseases in poultry. Also provided are immunogenic compositions comprising such recombinant viral vectors and methods for preventing or inhibiting Marek's disease in combination with at least a second disease in poultry.
    Type: Grant
    Filed: October 14, 2020
    Date of Patent: September 6, 2022
    Assignee: The Texas A&M University System
    Inventors: Sanjay M. Reddy, Blanca M. Lupiani
  • Patent number: 11421225
    Abstract: In an embodiment, a device for modulating intracellular gene expression, the device having a calcium actuator component and a transcription reprogramming component. In another embodiment, a method for modulating intracellular gene expression, where the method includes inducing a system having a calcium actuator component and a transcription reprogramming component with at least one of light and a chemical, causing an increase in Ca2+, and translocating the transcription reprogramming component from cytosol to the nucleus.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: August 23, 2022
    Assignee: The Texas A&M University System
    Inventors: Yubin Zhou, Yun Huang, Nhung T. Nguyen, Lian He
  • Patent number: 11420205
    Abstract: An instrument for energizing molecules contained in a sample solution may include a droplet generator configured to generate droplets of the sample solution. The droplet generator illustratively has an elongated nozzle defining an orifice at one end thereof from which the droplets exit the droplet generator, and the orifice illustratively defines a first longitudinal axis centrally therethrough. A molecule energizing source is configured to produce a molecule energizing field, and is positioned relative to the nozzle orifice such that the molecule energizing field extends into at least some of the generated droplets along a direction non-parallel with the first longitudinal axis. The molecule energizing field illustratively carries energy which heats at least one of the generated droplets sufficiently to induce structural changes in at least one molecule contained in the at least one of the generated droplets.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: August 23, 2022
    Assignees: Indiana University Research and Technology Corp., The Texas A&M University System
    Inventors: David E. Clemmer, Tarik J. El-Baba, Daniel R. Fuller, Daniel W. Woodall, David H. Russell, Evan R. Williams
  • Publication number: 20220259585
    Abstract: Embodiments of the present disclosure pertain to methods of constructing a phage display library where at least 90% of combinatorial regions in the phage display library include at least one in-frame amber codon. Further embodiments of the present disclosure pertain to the formed phage display libraries. Additional embodiments of the present disclosure pertain to methods of selecting peptides or proteins that bind to a desired target (e.g., a ligand binding site of a desired target) by utilizing the phage display libraries of the present disclosure. Further embodiments of the present disclosure pertain to peptides that have been screened from the phage display libraries and methods of the present disclosure, such as inhibitors of sirtuin 2, or inhibitors of ENL.
    Type: Application
    Filed: March 4, 2020
    Publication date: August 18, 2022
    Applicant: The Texas A&M University System
    Inventor: Wenshe Liu
  • Publication number: 20220259503
    Abstract: Hydrocarbon conversion and transportation methods and apparatuses are provided. An apparatus may apply electron beam irradiation to hydrocarbons (i.e., natural gas) to convert the hydrocarbons to liquid fuel. Lower-weight hydrocarbons may be converted into medium-weight organics through a gas to liquid process (GTL). The electrons may generate radicals that facilitate desired reactions. The hydrocarbons may be temperature and pressure controlled. For example, the hydrocarbons may be at lower temperatures (e.g., cryogenic or otherwise below ambient) and/or at higher pressures (e.g., greater than standard atmospheric pressures). Temperature suppression may reduce decomposition reactions. A high energy electron beam (e.g., 500 keV or higher, such as 10 MeV) could be used for the conversion process. The hydrocarbon may be liquefied. The liquid-like, higher density lower-weight hydrocarbons may lead to radical-neutral interactions.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 18, 2022
    Applicant: The Texas A&M University System
    Inventors: David Staack, Kunpeng WANG
  • Publication number: 20220252457
    Abstract: A passive infrared (PIR) sensor system, includes a PIR sensor configured to produce an output signal in response to receiving infrared (IR) radiation, an electronic shutter positionable in a field of view (FOV) of the PIR sensor, wherein the electronic shutter includes a liquid crystal (LC) material, wherein the electronic shutter includes a first state providing a first transmissivity of IR radiation through the electronic shutter and a second state providing a second transmissivity of IR radiation through the electronic shutter that is less than the first transmissivity, and a shutter actuator configured to apply an actuation signal to the electronic shutter to actuate the electronic shutter between the first state and the second state.
    Type: Application
    Filed: June 19, 2020
    Publication date: August 11, 2022
    Applicant: The Texas A&M University System
    Inventors: Ya Wang, Libo Wu, Zhangjie Chen
  • Patent number: PP34672
    Abstract: ‘DALBG 1201’ is an F1 hybrid bluegrass with exceptional turfgrass quality, dark green color, high shoot density, medium-fine leaf texture, and ability to persist under a range of environmental stresses typically encountered in the southern United States.
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: October 18, 2022
    Assignee: The Texas A&M University System
    Inventors: Ambika Chandra, James C. Read