Patents Assigned to TEXAS MEDICAL CENTER
  • Patent number: 11925731
    Abstract: Provided are methods, devices and compositions for reducing and/or inhibiting postsurgical tissue adhesion using a hydrogel film disposed onto a target tissue, thereby providing an adhesion barrier that remains over said target tissue for a prescribed period of time. In some embodiments, the hydrogel film is formed by the gelation of a pre-gel mixture applied onto the target tissue as a plurality of particles having an average maximum dimension, such as diameter, of at most about 500 ?m. In some embodiments, the hydrogel film has a minimum storage modulus of 100 Pa. In some embodiments, the pre-gel mixture comprises an ECM digest having a collagen to carbohydrate ratio (by mass) of at least 70:1.
    Type: Grant
    Filed: August 26, 2022
    Date of Patent: March 12, 2024
    Assignee: TEXAS MEDICAL CENTER
    Inventors: Timothy J. Keane, Jr., Peter Alexander Smith, Stephen G. Ramon
  • Patent number: 11179097
    Abstract: Tactile sensing devices, systems, and methods to image a target tissue location are disclosed. When force is applied to the tactile sensing device, voltage data is detected and visualized on a screen, indicating the target tissue location.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: November 23, 2021
    Assignee: TEXAS MEDICAL CENTER
    Inventors: Nicole C. Moskowitz, Jessica Traver, Xavier Garcia-Rojas, Yashar Ganjeh
  • Publication number: 20200360670
    Abstract: Provided herein are catheter devices, systems, and methods to ablate a tissue location. The devises, systems, and methods disclosed herein comprise catheters comprising a fenestrated nozzle, ablation balloons, and an ablation medium that is directed at a tissue location.
    Type: Application
    Filed: August 7, 2020
    Publication date: November 19, 2020
    Applicant: Texas Medical Center
    Inventors: Benjamin Morgan LEGUM, Shadi SHARIATNIA, Matthew Aria NOJOOMI, Kovi Ethan BESSOFF
  • Patent number: 10004450
    Abstract: Tactile sensing devices, systems, and methods to image a target tissue location are disclosed. When force is applied to the tactile sensing device, voltage data is detected and visualized on a screen, indicating the target tissue location.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: June 26, 2018
    Assignee: TEXAS MEDICAL CENTER
    Inventors: Nicole C. Moskowitz, Jessica Traver, Xavier Garcia-Rojas, Yashar Ganjeh
  • Publication number: 20030157717
    Abstract: Linear double-stranded DNA fragments containing a promoter, a nucleotide sequence, such as a transgene, preferably non-viral, and a 3′ untranslated region, are delivered to tissue of an animal by direct injection accompanied by electroporation. Long-term expression of the transgene results in prolonged availability of proteins, hormones, or enzymes that may be deficient in the mammal. In addition, the linear fragments increase the safety of the vectors for mammalian gene therapy by avoiding deleterious side effects.
    Type: Application
    Filed: September 6, 2002
    Publication date: August 21, 2003
    Applicant: Baylor College of Medicine Texas Medical Center
    Inventor: Ruxandra Draghia-Akli
  • Patent number: 5571697
    Abstract: The subject invention provides for the production of lactoferrins and lactoferrin polypeptide fragments using the host cells Aspergillus in combination with novel plasmid constructs. More specifically, the subject invention provides novel vector constructs capable of producing lactoferrins and lactoferrin polypeptide fragments in Aspergillus host cells. More particularly, the subject invention provides for novel plasmid constructs suitable for use with Aspergillus and especially Aspergillus awamori, niger and oryzae host cells, which enables them to produce large amounts of recombinant lactoferrins and lactoferrin polypeptide fragments.
    Type: Grant
    Filed: November 2, 1994
    Date of Patent: November 5, 1996
    Assignee: Baylor College of Medicine Texas Medical Center
    Inventors: Orla M. Conneely, Denis R. Headon, Bert W. O'Malley
  • Patent number: 5524445
    Abstract: A refrigerant leak detection apparatus and method for testing for leaking frigerant within a heat exchanging fluid, particularly for testing for leaking refrigerant in a chiller system comprising heat exchangers.
    Type: Grant
    Filed: March 31, 1995
    Date of Patent: June 11, 1996
    Assignee: Texas Medical Center Central Heating and Cooling Cooperative Association
    Inventors: Gordon R. Morrow, Coy M. White
  • Patent number: 5351500
    Abstract: A refrigerant leak detection apparatus and method for testing for leaking frigerant within a heat exchanging fluid, particularly for testing for leaking refrigerant in a chiller system comprising heat exchangers.
    Type: Grant
    Filed: December 3, 1993
    Date of Patent: October 4, 1994
    Assignee: Texas Medical Center Central Heating and Cooling Cooperative Association
    Inventor: Gordon R. Morrow