Patents Assigned to TFCHEM
  • Publication number: 20240124510
    Abstract: The present invention relates to compounds of the following formula (I): as well as their preparation process; their use in cosmetic or dermatological applications, in particular for the treatment and/or prevention of skin aging, skin protection or skin regeneration; for skin plumping and/or skin volumizing and/or skin densifying, and/or wrinkle filling and/or skin or hair moisturising and/or skin or hair relipiding and/or stimulation of hair growth; for the treatment of dry skin and/or atopic dermatitis and/or eczema and/or psoriasis; for the treatment and/or prevention of a fibrosis disease (e.g. an excessive scar such as a keloid or hypertrophic scar) or for healing; or for the treatment of inflammation (e.g. chronic, low-grade inflammation); and their use as adjuvant for preservation and/or protection and/or regeneration of a biological material or a microorganism.
    Type: Application
    Filed: January 20, 2022
    Publication date: April 18, 2024
    Applicant: TFCHEM
    Inventors: Géraldine Deliencourt Godefroy, Jocelyne Legoedec, Lénaïg Lopes
  • Publication number: 20220267380
    Abstract: The present invention relates to a glycopeptide of the following formula I: or a tautomer, a stereoisomer or a mixture of stereoisomers thereof in any proportions, in particular a mixture of enantiomers, and particularly a racemate mixture, and/or a physiologically acceptable salt and/or solvate thereof, in which:—n represents an integer from 1 to 6,—m represents 0 or 1,10—p represents 0 or 1—R represents H, F, CH3, CH2F, or CH2OH,—R1, R2 and R3 represent, independently from one another, H, F, or OH,—R4 represents a hydrogen, a halogen, or OH,—R6 and R7 represent, independently from each other, a hydrogen, a (C1-C6)alkyl, an aryl, or an aryl-(C1-C6)alkyl, and—R8 represents H or a CO-(C1-C20)alkyl, useful for skin plumping and/or skin volumizing and/or skin densifying and/or wrinkle filling and/or skin or hair moisturizing and/or skin or hair relipiding and/or stimulation of hair growth and/or for the treatment of dry skin and/or atopic dermatitis and/or atopic eczema and/or psoriasis, due to its ability to in
    Type: Application
    Filed: July 17, 2020
    Publication date: August 25, 2022
    Applicant: TFCHEM
    Inventors: Géraldine Deliencourt-Godefroy, Jocelyne Legoedec
  • Patent number: 10744181
    Abstract: The present invention relates to a compound of the following formula (I), as well as to a pharmaceutical composition comprising at least one compound of following formula (I) and at least one pharmaceutically acceptable excipient, for use in the treatment and/or prevention and/or attenuation of fibrosis diseases, in particular excessive scars such as keloids or hypertrophic scars.
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: August 18, 2020
    Assignee: TFCHEM
    Inventors: Géraldine Deliencourt-Godefroy, Jocelyne Legoedec
  • Patent number: 10640441
    Abstract: The present invention relates to a compound having the following formula (I) as well as a method for preparing such a compound, a cosmetic or pharmaceutical composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: May 5, 2020
    Assignee: TFCHEM
    Inventors: Geraldine Deliencourt-Godefroy, Lenaig Lopes
  • Publication number: 20190388501
    Abstract: The present invention relates to a compound of the following formula (I), as well as to a pharmaceutical composition comprising at least one compound of following formula (I) and at least one pharmaceutically acceptable excipient, for use in the treatment and/or prevention and/or attenuation of fibrosis diseases, in particular excessive scars such as keloids or hypertrophic scars.
    Type: Application
    Filed: January 30, 2017
    Publication date: December 26, 2019
    Applicant: TFCHEM
    Inventors: Géraldine Deliencourt-Godefroy, Jocelyne Legoedec
  • Publication number: 20190322608
    Abstract: The present invention relates to a compound having the following formula (I) as well as a method for preparing such a compound, a cosmetic or pharmaceutical composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.
    Type: Application
    Filed: August 24, 2017
    Publication date: October 24, 2019
    Applicant: TFCHEM
    Inventors: Geraldine DELIENCOURT-GODEFROY, Lenaig LOPES
  • Patent number: 10351501
    Abstract: The present invention relates to a compound having the formula (I), as well as a method for preparing such a compound, a cosmetic or pharmaceutic composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: July 16, 2019
    Assignee: TFCHEM
    Inventors: Géraldine Deliencourt-Godefroy, Lénaïg Lopes
  • Patent number: 10100088
    Abstract: The present invention relates to a compound of the following formula (I): in which at least one and only one group chosen among R5, R6 and R7 is a group of the following formula: The present invention relates also to uses thereof for preservation and/or protection and/or regeneration of biological materials and or microorganisms and for cosmetic or dermatological applications such as anti-aging, skin protection and skin regeneration; to culture, storage and/or preservation media comprising such a compound; to cosmetic or dermatological compositions comprising such a compound; to processes for preparing such a compound; and to synthesis intermediates.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: October 16, 2018
    Assignee: TFCHEM
    Inventors: Geraldine Deliencourt-Godefroy, Thibaut Martin
  • Publication number: 20180029967
    Abstract: The present invention relates to a compound having the formula (I), as well as a method for preparing such a compound, a cosmetic or pharmaceutic composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.
    Type: Application
    Filed: March 4, 2016
    Publication date: February 1, 2018
    Applicant: TFCHEM
    Inventors: Géraldine DELIENCOURT-GODEFROY, Lénaïg LOPES
  • Publication number: 20170015709
    Abstract: The present invention relates to a compound of the following formula (I): in which at least one and only one group chosen among R5, R6 and R7 is a group of the following formula: The present invention relates also to uses thereof for preservation and/or protection and/or regeneration of biological materials and or microorganisms and for cosmetic or dermato logical applications such as anti-aging, skin protection and skin regeneration; to culture, storage and/or preservation media comprising such a compound; to cosmetic or dermato logical compositions comprising such a compound; to processes for preparing such a compound; and to synthesis intermediates.
    Type: Application
    Filed: March 17, 2015
    Publication date: January 19, 2017
    Applicant: TFCHEM
    Inventors: Geraldine Deliencourt-Godefroy, Thibaut Martin
  • Patent number: 9434670
    Abstract: The present invention relates to a compound of the following formula (I): as well as its process of preparation, pharmaceutical and cosmetics composition comprising it and use thereof, notably as an inhibitor of the sodium-dependent glucose co-transporter, such as SGLT1, SGLT2 and SGLT3, in particular in the treatment or prevention of diabetes, and more particularly type-II diabetes, diabetes-related complications, such as arthritis of the lower extremities, cardiac infarction, renal insufficiency, neuropathy or blindness, hyperglycemia, hyperinsulinemia, obesity, hypertriglyceridemia, X syndrome and arteriosclerosis, as well as for its use as an anticancer, anti-infective, anti-viral, anti-thrombotic or anti-inflammatory drug, or for lightening, bleaching, depigmenting the skin, removing blemishes from the skin, particularly age spots and freckles, or preventing pigmentation of the skin.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: September 6, 2016
    Assignee: TFCHEM
    Inventors: Geraldine Deliencourt-Godefroy, Lenaig Lopes
  • Patent number: 9175044
    Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, as well as to their process of preparation, their use in the peptide synthesis, said peptide and the use of said peptide.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: November 3, 2015
    Assignee: TFCHEM
    Inventors: Geraldine Deliencourt-Godefroy, Hyacinthe Fillon, Thibaut Martin
  • Patent number: 9062313
    Abstract: The present invention concerns compounds of the following formula (I) or a pharmaceutically acceptable salt thereof, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, in which R represents H, OH or OR19, as well as processes for preparing these compounds and their use as inducer for the transcription of genes under control of the lac promoter.
    Type: Grant
    Filed: August 8, 2012
    Date of Patent: June 23, 2015
    Assignee: TFCHEM
    Inventors: Géraldine Deliencourt-Godefroy, Hyacinthe Fillon
  • Publication number: 20140199727
    Abstract: The present invention concerns compounds of the following formula (I) or a pharmaceutically acceptable salt thereof, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, in which R represents H, OH or OR19, as well as processes for preparing these compounds and their use as inducer for the transcription of genes under control of the lac promoter.
    Type: Application
    Filed: August 8, 2012
    Publication date: July 17, 2014
    Applicant: TFCHEM
    Inventors: Geraldine Deliencourt-Godefroy, Hyacinthe Fillon
  • Patent number: 8486897
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof, for use in the prevention and treatment of diseases including diabetes.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: July 16, 2013
    Assignee: TFCHEM
    Inventor: Géraldine Castelot-Deliencourt-Godefroy
  • Publication number: 20130171180
    Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, as well as to their process of preparation, their use in the peptide synthesis, said peptide and the use of said peptide.
    Type: Application
    Filed: December 22, 2011
    Publication date: July 4, 2013
    Applicant: TFCHEM
    Inventors: Geraldine Deliencourt-Godefroy, Hyacinthe Fillon, Thibaut Martin
  • Publication number: 20090318678
    Abstract: The invention concerns a C-glycoside compound of formula (I); wherein: n is equal to 1 or 2; Y represents H or halogen; X is an alkyl chain bearing at least one amino, amide, acid, ester, carbonyl, alcohol, aryl function or a carbonyl, ester amide, amino, alcohol group; the R's, identical or different, represent a OH or OR? group where R? is an alkyl, benzyl, benzoyl, acetyl, pivaloyl, trialkylsilyl, tertiobutyldiphenylsilyl group or one or more sugars; R1 represents OR?, NR?R??, N3, or a phthalamide with R? and R??, identical or different, represent H or an alkyl, aryl, benzyl, benzoyl, acetyl, alkoxycarbonyl, allyloxycarbonyl, benzyloxycarbonyl group; R2 represents H or halogen or a OH, OR, NR?R?? or N3 group, as well as derivatives thereof in physiologically or pharmaceutically acceptable base, mineral or organic acid-addition salt, hydrate or solvate form.
    Type: Application
    Filed: April 23, 2007
    Publication date: December 24, 2009
    Applicant: TFCHEM
    Inventors: Géraldine Castelot-Deliencourt-Godefroy, Jean-Charles Quirion, Philippe Jubault, Ludivine Zoute