Patents Assigned to TFCHEM
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Publication number: 20240124510Abstract: The present invention relates to compounds of the following formula (I): as well as their preparation process; their use in cosmetic or dermatological applications, in particular for the treatment and/or prevention of skin aging, skin protection or skin regeneration; for skin plumping and/or skin volumizing and/or skin densifying, and/or wrinkle filling and/or skin or hair moisturising and/or skin or hair relipiding and/or stimulation of hair growth; for the treatment of dry skin and/or atopic dermatitis and/or eczema and/or psoriasis; for the treatment and/or prevention of a fibrosis disease (e.g. an excessive scar such as a keloid or hypertrophic scar) or for healing; or for the treatment of inflammation (e.g. chronic, low-grade inflammation); and their use as adjuvant for preservation and/or protection and/or regeneration of a biological material or a microorganism.Type: ApplicationFiled: January 20, 2022Publication date: April 18, 2024Applicant: TFCHEMInventors: Géraldine Deliencourt Godefroy, Jocelyne Legoedec, Lénaïg Lopes
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Publication number: 20220267380Abstract: The present invention relates to a glycopeptide of the following formula I: or a tautomer, a stereoisomer or a mixture of stereoisomers thereof in any proportions, in particular a mixture of enantiomers, and particularly a racemate mixture, and/or a physiologically acceptable salt and/or solvate thereof, in which:—n represents an integer from 1 to 6,—m represents 0 or 1,10—p represents 0 or 1—R represents H, F, CH3, CH2F, or CH2OH,—R1, R2 and R3 represent, independently from one another, H, F, or OH,—R4 represents a hydrogen, a halogen, or OH,—R6 and R7 represent, independently from each other, a hydrogen, a (C1-C6)alkyl, an aryl, or an aryl-(C1-C6)alkyl, and—R8 represents H or a CO-(C1-C20)alkyl, useful for skin plumping and/or skin volumizing and/or skin densifying and/or wrinkle filling and/or skin or hair moisturizing and/or skin or hair relipiding and/or stimulation of hair growth and/or for the treatment of dry skin and/or atopic dermatitis and/or atopic eczema and/or psoriasis, due to its ability to inType: ApplicationFiled: July 17, 2020Publication date: August 25, 2022Applicant: TFCHEMInventors: Géraldine Deliencourt-Godefroy, Jocelyne Legoedec
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Patent number: 10744181Abstract: The present invention relates to a compound of the following formula (I), as well as to a pharmaceutical composition comprising at least one compound of following formula (I) and at least one pharmaceutically acceptable excipient, for use in the treatment and/or prevention and/or attenuation of fibrosis diseases, in particular excessive scars such as keloids or hypertrophic scars.Type: GrantFiled: January 30, 2017Date of Patent: August 18, 2020Assignee: TFCHEMInventors: Géraldine Deliencourt-Godefroy, Jocelyne Legoedec
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Patent number: 10640441Abstract: The present invention relates to a compound having the following formula (I) as well as a method for preparing such a compound, a cosmetic or pharmaceutical composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.Type: GrantFiled: August 24, 2017Date of Patent: May 5, 2020Assignee: TFCHEMInventors: Geraldine Deliencourt-Godefroy, Lenaig Lopes
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Publication number: 20190388501Abstract: The present invention relates to a compound of the following formula (I), as well as to a pharmaceutical composition comprising at least one compound of following formula (I) and at least one pharmaceutically acceptable excipient, for use in the treatment and/or prevention and/or attenuation of fibrosis diseases, in particular excessive scars such as keloids or hypertrophic scars.Type: ApplicationFiled: January 30, 2017Publication date: December 26, 2019Applicant: TFCHEMInventors: Géraldine Deliencourt-Godefroy, Jocelyne Legoedec
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Publication number: 20190322608Abstract: The present invention relates to a compound having the following formula (I) as well as a method for preparing such a compound, a cosmetic or pharmaceutical composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.Type: ApplicationFiled: August 24, 2017Publication date: October 24, 2019Applicant: TFCHEMInventors: Geraldine DELIENCOURT-GODEFROY, Lenaig LOPES
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Patent number: 10351501Abstract: The present invention relates to a compound having the formula (I), as well as a method for preparing such a compound, a cosmetic or pharmaceutic composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.Type: GrantFiled: March 4, 2016Date of Patent: July 16, 2019Assignee: TFCHEMInventors: Géraldine Deliencourt-Godefroy, Lénaïg Lopes
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Patent number: 10100088Abstract: The present invention relates to a compound of the following formula (I): in which at least one and only one group chosen among R5, R6 and R7 is a group of the following formula: The present invention relates also to uses thereof for preservation and/or protection and/or regeneration of biological materials and or microorganisms and for cosmetic or dermatological applications such as anti-aging, skin protection and skin regeneration; to culture, storage and/or preservation media comprising such a compound; to cosmetic or dermatological compositions comprising such a compound; to processes for preparing such a compound; and to synthesis intermediates.Type: GrantFiled: March 17, 2015Date of Patent: October 16, 2018Assignee: TFCHEMInventors: Geraldine Deliencourt-Godefroy, Thibaut Martin
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Publication number: 20180029967Abstract: The present invention relates to a compound having the formula (I), as well as a method for preparing such a compound, a cosmetic or pharmaceutic composition containing such a compound, and the use thereof as a depigmenting, lightening, bleaching or whitening agent and for treating pigmentation disorders, notably by topical application on the skin.Type: ApplicationFiled: March 4, 2016Publication date: February 1, 2018Applicant: TFCHEMInventors: Géraldine DELIENCOURT-GODEFROY, Lénaïg LOPES
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Publication number: 20170015709Abstract: The present invention relates to a compound of the following formula (I): in which at least one and only one group chosen among R5, R6 and R7 is a group of the following formula: The present invention relates also to uses thereof for preservation and/or protection and/or regeneration of biological materials and or microorganisms and for cosmetic or dermato logical applications such as anti-aging, skin protection and skin regeneration; to culture, storage and/or preservation media comprising such a compound; to cosmetic or dermato logical compositions comprising such a compound; to processes for preparing such a compound; and to synthesis intermediates.Type: ApplicationFiled: March 17, 2015Publication date: January 19, 2017Applicant: TFCHEMInventors: Geraldine Deliencourt-Godefroy, Thibaut Martin
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Patent number: 9434670Abstract: The present invention relates to a compound of the following formula (I): as well as its process of preparation, pharmaceutical and cosmetics composition comprising it and use thereof, notably as an inhibitor of the sodium-dependent glucose co-transporter, such as SGLT1, SGLT2 and SGLT3, in particular in the treatment or prevention of diabetes, and more particularly type-II diabetes, diabetes-related complications, such as arthritis of the lower extremities, cardiac infarction, renal insufficiency, neuropathy or blindness, hyperglycemia, hyperinsulinemia, obesity, hypertriglyceridemia, X syndrome and arteriosclerosis, as well as for its use as an anticancer, anti-infective, anti-viral, anti-thrombotic or anti-inflammatory drug, or for lightening, bleaching, depigmenting the skin, removing blemishes from the skin, particularly age spots and freckles, or preventing pigmentation of the skin.Type: GrantFiled: May 29, 2012Date of Patent: September 6, 2016Assignee: TFCHEMInventors: Geraldine Deliencourt-Godefroy, Lenaig Lopes
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Patent number: 9175044Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, as well as to their process of preparation, their use in the peptide synthesis, said peptide and the use of said peptide.Type: GrantFiled: December 22, 2011Date of Patent: November 3, 2015Assignee: TFCHEMInventors: Geraldine Deliencourt-Godefroy, Hyacinthe Fillon, Thibaut Martin
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Patent number: 9062313Abstract: The present invention concerns compounds of the following formula (I) or a pharmaceutically acceptable salt thereof, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, in which R represents H, OH or OR19, as well as processes for preparing these compounds and their use as inducer for the transcription of genes under control of the lac promoter.Type: GrantFiled: August 8, 2012Date of Patent: June 23, 2015Assignee: TFCHEMInventors: Géraldine Deliencourt-Godefroy, Hyacinthe Fillon
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Publication number: 20140199727Abstract: The present invention concerns compounds of the following formula (I) or a pharmaceutically acceptable salt thereof, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, in which R represents H, OH or OR19, as well as processes for preparing these compounds and their use as inducer for the transcription of genes under control of the lac promoter.Type: ApplicationFiled: August 8, 2012Publication date: July 17, 2014Applicant: TFCHEMInventors: Geraldine Deliencourt-Godefroy, Hyacinthe Fillon
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Patent number: 8486897Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof, for use in the prevention and treatment of diseases including diabetes.Type: GrantFiled: April 2, 2009Date of Patent: July 16, 2013Assignee: TFCHEMInventor: Géraldine Castelot-Deliencourt-Godefroy
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Publication number: 20130171180Abstract: The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, a tautomer, a stereoisomer or a mixture of stereoisomers in any proportion, in particular a mixture of enantiomers, and particularly a racemate mixture, as well as to their process of preparation, their use in the peptide synthesis, said peptide and the use of said peptide.Type: ApplicationFiled: December 22, 2011Publication date: July 4, 2013Applicant: TFCHEMInventors: Geraldine Deliencourt-Godefroy, Hyacinthe Fillon, Thibaut Martin
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Publication number: 20090318678Abstract: The invention concerns a C-glycoside compound of formula (I); wherein: n is equal to 1 or 2; Y represents H or halogen; X is an alkyl chain bearing at least one amino, amide, acid, ester, carbonyl, alcohol, aryl function or a carbonyl, ester amide, amino, alcohol group; the R's, identical or different, represent a OH or OR? group where R? is an alkyl, benzyl, benzoyl, acetyl, pivaloyl, trialkylsilyl, tertiobutyldiphenylsilyl group or one or more sugars; R1 represents OR?, NR?R??, N3, or a phthalamide with R? and R??, identical or different, represent H or an alkyl, aryl, benzyl, benzoyl, acetyl, alkoxycarbonyl, allyloxycarbonyl, benzyloxycarbonyl group; R2 represents H or halogen or a OH, OR, NR?R?? or N3 group, as well as derivatives thereof in physiologically or pharmaceutically acceptable base, mineral or organic acid-addition salt, hydrate or solvate form.Type: ApplicationFiled: April 23, 2007Publication date: December 24, 2009Applicant: TFCHEMInventors: Géraldine Castelot-Deliencourt-Godefroy, Jean-Charles Quirion, Philippe Jubault, Ludivine Zoute