Abstract: The invention is directed to novel crystalline forms of lamotrigine. These novel crystalline forms of lamotrigine have improved dissolution and in-vivo absorption profile, as compared to pure lamotrigine. These novel crystalline forms of lamotrigine provide a substantial increase in the blood concentration of lamotrigine, as compared to pure lamotrigine when administered to a subject. These novel crystalline forms of lamotrigine also provide a slower, steady build up of lamotrigine blood concentration suitable for sustained release of lamotrigine in-vivo, as compared to pure lamotrigine.
Type:
Grant
Filed:
November 10, 2008
Date of Patent:
July 16, 2013
Assignee:
Thar Pharmaceuticals
Inventors:
Mazen Hanna, Ning Shan, Miranda L. Cheney
Abstract: The invention is directed to novel crystalline forms of meloxicam. These novel crystalline forms of meloxicam have improved bioavailability, an enhanced rate of dissolution and shorter time to Cmax in blood, as compared to pure meloxicam.
Type:
Grant
Filed:
February 17, 2012
Date of Patent:
March 5, 2013
Assignee:
Thar Pharmaceuticals
Inventors:
Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna
Abstract: The invention is directed to novel crystalline forms of meloxicam. These novel crystalline forms of meloxicam have improved bioavailability, an enhanced rate of dissolution and shorter time to Cmax in blood, as compared to pure meloxicam.
Type:
Application
Filed:
February 17, 2012
Publication date:
June 14, 2012
Applicant:
THAR PHARMACEUTICALS
Inventors:
Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna
Abstract: The invention is directed to novel crystalline forms of meloxicam. These novel crystalline forms of meloxicam have improved bioavailability, an enhanced rate of dissolution and shorter time to Cmax in blood, as compared to pure meloxicam.
Type:
Grant
Filed:
January 22, 2009
Date of Patent:
February 28, 2012
Assignee:
Thar Pharmaceuticals
Inventors:
Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna
Abstract: The invention is directed to novel crystalline forms of meloxicam. These novel crystalline forms of meloxicam have improved bioavailability, an enhanced rate of dissolution and shorter time to Cmax in blood, as compared to pure meloxicam.
Type:
Application
Filed:
January 22, 2009
Publication date:
August 13, 2009
Applicant:
Thar Pharmaceuticals
Inventors:
Mazen Hanna, Ning Shan, Miranda L. Cheney, David R. Weyna
Abstract: The invention is directed to novel crystalline forms of lamotrigine. These novel crystalline forms of lamotrigine have improved dissolution and in-vivo absorption profile, as compared to pure lamotrigine. These novel crystalline forms of lamotrigine provide a substantial increase in the blood concentration of lamotrigine, as compared to pure lamotrigine when administered to a subject. These novel crystalline forms of lamotrigine also provide a slower, steady build up of lamotrigine blood concentration suitable for sustained release of lamotrigine in-vivo, as compared to pure lamotrigine.
Type:
Application
Filed:
November 10, 2008
Publication date:
July 9, 2009
Applicant:
Thar Pharmaceuticals
Inventors:
Mazen Hanna, Ning Shan, Miranda L. Cheney