Abstract: An apparatus (1) for performing manometric measurements by way of medical devices of the pneumatic type, comprises a processing unit (10), and a pressure transducer (4), which is connected to the unit (10) and adapted to be fluid-dynamically connected to the pneumatic device (3). The processing unit (10) comprises: a setting module (11) configured for setting a reference parameter, which is a function of conformational and/or dimensional features of the device (3); and a measurement module (12) configured for processing the measurements made by the transducer (4), according to the reference parameters (a, b, c) which were set for calculating respective objective pressure values. The medical device (3) of the pneumatic type is fluid-dynamically connectable to a measurement apparatus (1), which is provided with an hollow and compressible active portion (30) and provided with an internal fluid-dynamic path adapted to put into communication the apparatus (1) with the cavity of the active portion (30).

Abstract: An in vitro method enables determination of the antibiotic resistance of Helicobacter pylorifor in a biological sample isolated from an individual. The method includes amplifying at least one portion of at least one gene of Helicobacter pylori. The at least one gene includes at least one mutation site responsible for resistance to an antibiotic. A kit can be used for performing the method.

Abstract: A system and method for managing use of medical devices. The system includes: an apparatus intended to be used in combination with one or more medical devices; one or more processing units; authorizing means, which may be associated to a medical device and including one identifier parameter able to uniquely identify said device. The processing unit includes: one reader module configured for acquiring the identifier parameter from the authorizing means; one enabling module configured to allow or inhibit use of the device with the apparatus on the basis of control parameters; and at least one calculation module configured for setting the number of uses of the device. The control parameters include the identifier parameter acquired and the number of uses calculated.

Abstract: A proctoscope, comprising a dilator body (2), having a longitudinal axis of extension (X) and internally hollow so as to define an internal volume (V), and at least one handle (5) applied to said dilator body (2), wherein the dilator body (2) has a distal portion (2a), having a substantially tubular shape and defining a zone of dilation of an internal cavity of a patient, and a proximal portion (2b) extending from the distal portion (2a) in a diverging fashion and defining a rear opening (4) for accessing said internal volume (V), wherein said distal portion (2a) of the dilator body (2) has at least one front opening (3) to enable access to the patient's mucosa or tissue from said internal volume (V), and wherein said diverging proximal portion (2b), or, alternatively, said at least one handle (5), has an anchorage means (6) for an adaptor body (100) suitable for placing a detection device (200) in a position such as to detect the internal volume of the proctoscope (1).

Abstract: A manometric probe, comprising: a main body (2) provided with a longitudinal axis (X); an extensible membrane (3) sealingly associated to at least two annular areas of the main body (2) so as to delimit a chamber (4) external to the main body (2); feed means (51,52) arranged so as to enable feeding of a fluid inside the chamber (4).

Abstract: A system for processing the manometric measurements carried out by way of an anorectal probe includes one or more processing units, which include: an acquisition module configured for acquiring management parameters of an anorectal manometry; a basal module configured for processing the manometric measurements acquired during the basal maneuver of anorectal manometry in accordance with the management parameters; a squeeze module configured for processing the manometric measurements acquired during the squeeze maneuver; an endurance module, configured for calculating the time interval between the instant at which a maximum value is measured during the squeeze maneuver, and the instant at which the pressure measured falls below a squeeze threshold; a strain module configured for processing the manometric measurements acquired during the strain maneuver; and a memory module configured for the registration of functions and/or indexes calculated by the modules while processing said measures.

Abstract: A method for producing an artificial sphincter comprises the steps of effecting a skin incision (2), forming a passage (3) for a prosthesis (4) and releasing the prosthesis (4) inside the passage (3). Said prosthesis passing from one miniaturized state in the step preceding the release, to an expanded state in the step following the release. The steps mentioned above are repeated at least seven times in order to release at least seven prosthesis (4), which are uniformly distributed along a circumferential arc (5) surrounding the anal canal (AC); said at least seven prosthesis (4) defining a plurality of prosthesis (40) forming a third artificial sphincter.

Abstract: A circuit for feeding a fluid to an inflatable chamber, comprising: a compressor (2); a two-way and two-position solenoid valve (3) provided with a first port (31) and a second port (32) and operable between an open configuration, in which the ports (31,32) are in communication with one another, and a closed configuration, in which at least the second port (32) is closed; a first conduit (11) connecting the compressor (2) and the solenoid valve (3); a second conduit (12) connected to the solenoid valve (3) and predisposed for being connected to an inflatable chamber; a pressure detector (P) arranged for measuring the pressure inside the second conduit (12); a control module (M) arranged for receiving a pressure signal of the detector (P) and for controlling the solenoid valve (3) and the compressor (2); a vent opening (A) arranged along the first conduit (11).

Abstract: A device for implanting a prosthesis 12 in a body tissue equipped with a tubular element 7, within which a prosthesis 12 can slide, and a pressure element 16 for moving said prosthesis 12. The device also comprises a cartridge 5 provided with a seat 31 at its interior, such seat housing the prosthesis 12 and movable under the action of a pusher element 13 from a first position, in which the seat 31 is not facing the tubular element 7, to a second position, in which the seat 31 is in communication with the tubular element 7 in order to allow the insertion of the prosthesis 12 inside the tubular element 7 upon command of the pressure element 16.

Abstract: A device for implanting a prosthesis 12 in a body tissue equipped with a tubular element 7, within which a prosthesis 12 can slide, and a pressure element 16 for moving said prosthesis 12. The device also comprises a cartridge 5 provided with a seat 31 at its interior, such seat housing the prosthesis 12 and movable under the action of a pusher element 13 from a first position, in which the seat 31 is not facing the tubular element 7, to a second position, in which the seat 31 is in communication with the tubular element 7 in order to allow the insertion of the prosthesis 12 inside the tubular element 7 upon command of the pressure element 16.

Abstract: A device for examining and surgically operating on a body cavity, in particular an anal or vaginal cavity, includes an elongate hollow body exhibiting an insertion portion for at least a partial insertion of the device internally of the cavity and an open portion, arranged on an opposite side to the insertion portion, through which the cavity is at least partially visible or reachable by at least a surgical instrument. At least a part of the hollow body exhibits a structural sector which is interposed between the insertion portion and the open portion in order to be positioned in the cavity. The structural sector has a longitudinal window through which a portion of the cavity affected by a pathology can be isolated.

Abstract: The present invention relates to a method for diagnosing a carcinoma or a residual disease associated thereto, or for the prognosis of a carcinoma, or for monitoring the effectiveness of an anti-tumour therapy directed against a carcinoma, or for monitoring the follow-up of an individual affected by a carcinoma, in particular colorectal carcinoma, carcinoma of the stomach, mammary carcinoma, pulmonary carcinoma or carcinoma of the prostate, carcinoma of the liver, carcinoma of the ovary, carcinoma of the kidney, carcinoma of the thyroid, carcinoma of the bladder or carcinoma of the pancreas. The method of the invention consists in placing adult stem cells in contact with a sample of a haemo-derivative of the individual to be analyzed and in verifying the expression of at least an epithelial marker in the stem cells by means of immunofluorescence, immunohistochemistry, ELISA or RT-PCR.

Abstract: The device for examining and surgically operating on body cavities, in particular the anal and vaginal cavities, comprises an elongate hollow body (2) exhibiting an insertion portion (3) for at least a partial insertion of the device (1) internally of the cavity and an open portion (4), through which the doctor or surgeon can operate. The hollow body (2) exhibits a longitudinal window (5) through which the pathological site of interest on the cavity wall can be isolated. The hollow body (2) exhibits, along the longitudinal window, a transversal section constituted by a curved sector, ends of which extend in a substantially parallel directions which diverge in such a way as to stretch the affected portion of cavity without invading the viewing space and/or the maneuvering space defined by the hollow body (2).

Abstract: A medical surgical device for coloproctological pathologies comprises a tubular body (2), provided with a first end (5), which can be inserted into the anal cavity, and a second end (6), opposite the first end (5) and connected to a handle (7) for maneuvering the tubular body (2) inside the anal cavity. A light source (8) for illuminating the inside of the tubular body (2) can be removably connected to the tubular body (2). Downstream of the light source (8) is located an entraining body (10) for entraining a portion of the light emitted by the light source (8) toward the inserting end (5). The entraining body (10) comprises a thickening (11) on the internal wall (3).

Abstract: A device for stretching a plastic ring which comprises pushing means (2) and a loading body (5) which are reciprocally slidable across a plurality of ribs (4) solidly constrained to the pushing means (2), and a plurality of grooves (6) afforded on the loading body (5). The loading body (5) exhibits a first substantially conical portion (7) exhibiting a base (7a), having an external diameter (D) and an apex (7b). The loading body (5) further comprises a second portion (8), contiguous to the first conical portion (7) and exhibiting a proximal end (8a) and a distal end (8b).

Abstract: A device for surgical operations on a prolapse, comprising a hollow stretcher body (2) having a prevalent development direction along a longitudinal axis (A) and being insertable in an orifice, the stretcher body (2) exhibiting a through-window (7), defining an area of intervention and realising a communication between an internal cavity (3) of the stretcher body (2) and a portion of a prolapse, a mobile wall (8) defining the through-window (7) in combination with the stretcher body (2) and being slidably associated to the stretcher body (2) in order to open and/or close the through window (7) between a configuration of minimum extension and a configuration of maximum extension of the through-window (7); characterized in that it comprises means for blocking (10) which act between the mobile wall (8) and the stretcher body (2) in order to maintain the through-window (7) stably in the configuration of minimum extension during insertion of the stretcher body (2).

Abstract: The present invention relates to a method for diagnosing a carcinoma or a residual disease associated thereto, or for the prognosis of a carcinoma, or for monitoring the effectiveness of an anti-tumour therapy directed against a carcinoma, or for monitoring the follow-up of an individual affected by a carcinoma, in particular colorectal carcinoma, carcinoma of the stomach, mammary carcinoma, pulmonary carcinoma or carcinoma of the prostate, carcinoma of the liver, carcinoma of the ovary, carcinoma of the kidney, carcinoma of the thyroid, carcinoma of the bladder or carcinoma of the pancreas. The method of the invention consists in placing adult stem cells in contact with a sample of a haemo-derivative of the individual to be analysed and in verifying the expression of at least an epithelial marker in the stem cells by means of immunofluorescence, immunohistochemistry, ELISA or RT-PCR.

Abstract: A medical device 1 for colo-proctological pathologies, comprising a retractor body 2, having a distal end 3 and a proximal end 4, a handle 7 connected to the retractor body 2, and illuminating means 16, located internally of a cavity 12 fashioned internally of the proximal end 4, for generating a light beam internally of the retractor body 2.

Abstract: A process for surgical operations on a rectal/haemorrhoidal prolapse comprises stages of realising, in the anal canal, at least a first circular stitching at a first portion of a haemorrhoidal prolapse; realising at least a second circular stitching in a second portion of the haemorrhoidal prolapse, and nearing the first circular stitching and the second circular stitching in order to create a constriction of the haemorrhoidal prolapse. The invention also relates to a device, preferably for actuating the process, which comprises a hollow divaricator (17) having a prevalent development direction along a longitudinal axis (Z) and being insertable in a patient's anal orifice. The device further exhibits a window (29) defining an operational area and creating a communication between a cavity (17b) internal of the divaricator (17) and a portion of haemorrhoidal prolapse. The device further comprises means for opening and closing (31) the window (29).