Abstract: Improving the balance of beneficial gut microbiota of an animal by providing a composition containing beta-casein, wherein at least 75% by weight of the beta-casein is a beta-casein variant that has a proline at position 67 of the beta-casein amino acid sequence.
Type:
Grant
Filed:
September 30, 2016
Date of Patent:
March 12, 2024
Assignee:
THE A2 MILK COMPANY LIMITED
Inventors:
Andrew John Clarke, Catherine Mary Babidge, Jiayi Ni
Abstract: The use of a composition for preventing or reducing the risk of inflammation of the bowel in an animal, wherein the composition contains beta-casein and wherein the beta-casein comprises at least 50% by weight beta-casein A2.
Type:
Grant
Filed:
February 7, 2020
Date of Patent:
February 27, 2024
Assignee:
THE A2 MILK COMPANY LIMITED
Inventors:
Andrew John Clarke, Malav Suchin Trivedi
Abstract: The disclosure provides a method of improving the cognitive function of an animal by providing a composition containing beta-casein, wherein at least 75% by weight of the beta-casein is a beta-casein variant that does not produce BCM-7 on digestion in the gut of the animal.
Type:
Grant
Filed:
March 29, 2017
Date of Patent:
November 22, 2022
Assignee:
THE A2 MILK COMPANY LIMITED
Inventors:
Andrew John Clarke, Gregory Wayne Yelland
Abstract: Improving the antioxidant capacity in an animal by increasing the level of glutathione in the blood or tissue of the animal comprising providing a composition containing beta-casein to the animal for consumption, where the beta-casein comprises at least 75% by weight of one or more beta-caseins not capable of producing beta-casomorphin-7 on enzymatic digestion. Uses include as an oxidant, for treating or preventing the symptoms of cancer, inflammation, kwashiorkor (protein deficiency), seizure, autism, Down's syndrome, chronic fatigue syndrome, Alzheimer's disease, Parkinson's disease, sickle cell anaemia, liver disease, cystic fibrosis, HIV, AIDS, infection, heart attack, stroke, and diabetes, avoiding or reducing the effects of aging, promoting the recovery of tissue following physical exercise, and promoting fertility.
Type:
Grant
Filed:
May 20, 2016
Date of Patent:
July 7, 2020
Assignee:
THE A2 MILK COMPANY LIMITED
Inventors:
Andrew John Clarke, Malav Suchin Trivedi
Abstract: Regulating the level of glucose in the blood of an animal comprising the consumption by the animal of a composition containing beta-casein, or providing the composition to the animal for consumption, where the beta-casein comprises at least 75% by weight beta-casein A2. Uses include managing the symptoms of hyperglycaemia and associated conditions including diabetes. The effect is both acute (post-exposure to the composition) and ongoing.
Type:
Grant
Filed:
August 22, 2014
Date of Patent:
February 25, 2020
Assignee:
THE A2 MILK COMPANY LIMITED
Inventors:
Andrew John Clarke, Malav Suchin Trivedi