Patents Assigned to The Arizona Board of Regents Acting on behalf of The
University of Arizona
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Publication number: 20160187293Abstract: An electrophoresis device where the end of the electrophoresis channel has a part that extends vertically. The electrophoresis channel includes a first access port at one end of the channel and a second port at the other end of the channel, which are in the same horizontal plane. In this way, there is a less than 0.1% hydrostatic pressure differential between two ports and the performance of the device is improved.Type: ApplicationFiled: June 11, 2012Publication date: June 30, 2016Applicants: The Arizona Board of Regents acting for and on behalf of University of Arizona, BioAccelInventors: Frederic ZENHAUSERN, Alan NORDQUIST, Ralf LENIGK, Cedric HURTH, Jianing YANG, Xiaojia CHEN, Matthew ESTES, John LEE-EDGHILL, Nina MORAN, Andrew HOPWOOD, Pieris KOUMI
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Patent number: 8586626Abstract: Novel metabolites of wortmannin and wortmannin analogs and their use in inhibiting PI-3 kinase activity in mammals and the treatment and prevention of cancer or tumor formation in a subject are described herein.Type: GrantFiled: June 10, 2011Date of Patent: November 19, 2013Assignee: Arizona Board of Regents, Acting on Behalf of the University of ArizonaInventor: Garth Powis
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Publication number: 20130210163Abstract: A method for collecting a sample and/or analysing a sample is provided, together with kits for use therein, in which the method includes using the kit and wherein an identifier is provided on one or more of the devices and/or containers and/or packaging which can be recorded and which is used to link the identity of the identifier for one or more of those identifiers to one or more of the identities for one or more of the other identifiers. In this way, the different devices, containers, pieces of equipment, reagents and stages used in the collection and/or analysis can be linked together for future reference. This ensures the correct processing of the sample and the correct attributing of the end results to it. Checks or other enquiries can be made on each of the different devices etc to validate the results if necessary.Type: ApplicationFiled: August 24, 2011Publication date: August 15, 2013Applicants: The Arizona Board of Regents Acting for and on behalf of University of Arizona, FORENSIC SCIENCE SERVICE LIMITEDInventors: Andrew Hopwood, Nina Moran, Pieris Koumi, John Lee-Edghill
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Patent number: 7858657Abstract: Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic agents in the treatment of cancer.Type: GrantFiled: September 23, 2008Date of Patent: December 28, 2010Assignees: Proix Pharmaceutical Corp., Arizona Board of Regents, Acting on Behalf of The University of Arizona, University of Pittsburgh - Of the Commonwealth System of Higher EducationInventors: Lynn D. Kirkpatrick, Garth Powis, Peter Wipf
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Patent number: 7723375Abstract: Novel metabolites of wortmannin and wortmannin analogs and their use in inhibiting PI-3 kinase activity in mammals and the treatment and prevention of cancer or tumor formation in a subject are described herein.Type: GrantFiled: December 29, 2006Date of Patent: May 25, 2010Assignee: Arizona Board of Regents, acting on behalf of The University of ArizonaInventor: Garth Powis
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Patent number: 7446124Abstract: Novel wortmannin analogs and their use in inhibiting PI-3-kinase activity in mammals and the treatment or prevention of cancer and tumor formation in a subject are described herein. Preferably, the wortmannin analogs may be administered with other chemotherapeutic agents in the treatment of cancer.Type: GrantFiled: July 11, 2005Date of Patent: November 4, 2008Assignees: Prolx Pharmaceuticals Corp., The University of Pittsburgh, Arizona Board of Regents, Acting on Behalf of the University of ArizonaInventors: Lynn Kirkpatrick, Garth Powis, Peter Wipf
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Publication number: 20080057564Abstract: The invention provides isolated nucleic acids and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content, cell cycle progression, cell number and/or composition of plants.Type: ApplicationFiled: July 5, 2007Publication date: March 6, 2008Applicants: Pioneer Hi-Bred International, Inc., The Arizona Board of Regents Acting on Behalf of the University of ArizonaInventors: William Gordon-Kamm, Keith Lowe, Brian Larkins, Brian Dilkes, Yuejin Sun
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Publication number: 20080060099Abstract: The invention provides isolated nucleic acids and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content, cell cycle progression, cell number and/or composition of plants.Type: ApplicationFiled: July 5, 2007Publication date: March 6, 2008Applicants: PIONEER HI-BRED INTERNATIONAL, INC., The Arizona Board of Regents Acting on Behalf of the University of ArizonaInventors: William Gordon-Kamm, Keith Lowe, Brian Larkins, Brian Dilkes, Yuejin Sun
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Patent number: 7081475Abstract: Novel Wortmannin analogs and their use in inhibiting inhibiting PI-3-kinase activity in mammals as well as tumor formation in a subject are described herein.Type: GrantFiled: September 16, 2002Date of Patent: July 25, 2006Assignees: Prolx Pharmaceuticals Corp., Arizona Board of Regents, Acting on behalf of the University of Arizona, University of PittsburghInventors: Garth Powis, Wipf Peter
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Patent number: 6730307Abstract: Compositions and methods useful for conferring passive or active immunity to the parasite, C. parvum. A high molecular weight glycoprotein antigen isolated from C. parvum, capable of binding the mAb 3E2, was shown to harbor an epitope critical for triggering the neutralizing CSP-like reaction in the parasite. Antibodies targeted against the critical epitope were shown to possess neutralizing activity, and could be combined with other anti-C. parvum monoclonal antibodies and administered to an animal to confer passive immunity. Immunogenic compositions including the purified antigen are disclosed for use in stimulating an active immune response against C. parvum.Type: GrantFiled: April 12, 2001Date of Patent: May 4, 2004Assignees: The Arizona Board of Regents Acting on Behalf of the University of Arizona, North Carolina State UniversityInventors: Michael W. Riggs, Lance E. Perryman
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Patent number: 6689775Abstract: The present invention relates to the use of thioredoxin as, inter alia, a cell growth stimulator, as well as a screen for agents that are useful in reducing or preventing thioredoxin-associated apoptosis inhibition and agents that are useful in inhibiting thioredoxin stimulated cell growth.Type: GrantFiled: June 6, 2001Date of Patent: February 10, 2004Assignee: Arizona Board of Regents, acting on behalf of the University of ArizonaInventor: Garth Powis
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Patent number: 6452070Abstract: The invention provides novel methods of using viral replicase polypeptides and polynucleotides. Included are methods for increasing transformation frequencies, increasing crop yield, providing a positive growth advantage, modulating cell division, transiently modulating cell division, and for providing a means of positive selection.Type: GrantFiled: July 27, 2000Date of Patent: September 17, 2002Assignees: Pioneer Hi-Bred International, Inc., The Arizona Board of Regents Acting on behalf of The University of ArizonaInventors: William J. Gordon-Kamm, Keith S. Lowe, Matthew A. Bailey, Carolyn A. Gregory, George J. Hoerster, Brian A. Larkins, Brian R. Dilkes, Ronald Burnett, Young Min Woo
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Patent number: 6112324Abstract: A system that redefines how data is distributed on a conventional writable compact disc (CD-R/E). A rearrangement of the data on the disc provided during the writing operation preserves eight-to-fourteen channel frames and the control and display (C&D) channel and burst error mitigation while providing a direct access storage device (DASD) format and capability. The CD-DASD format is suitable for preformatting the CDs and has constant size sectors recorded contiguously along the spiral track. Each sector is independently addressable and synchronous with the C&D data word and ATIP channel words on the CD-R disc. The system uses the components of a conventional CD device and a mapping controller address translator to encode and decode the data bytes using a conventional CIRC encoder/decoder. A rectangular product code of C1 and C2 CIRC subcodes is provided that is interleaved to mitigate the effects of handling.Type: GrantFiled: February 2, 1996Date of Patent: August 29, 2000Assignee: The Arizona Board of Regents acting on behalf of The University of ArizonaInventors: Dennis George Howe, Babak Tehranchi
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Patent number: 5744267Abstract: A photorefractive (PR) device comprises of a layer of a novel photorefractive polymer composite sandwiched inbetween two transparent electrodes. The PR polymer composite comprises a photoconducting polymer, a photosensitizer, a novel second-order, non-linear optical chromophore, and a plasticizer in an amount sufficient to provide the PR polymer composite with a glass transition temperature below about 45.degree. C. The PR polymer composite is capable of internally storing image patterns generated by interfering two coherent light beams inside the material. The PR polymer composite shows high diffraction efficiencies (near 100%) and high net two-coupling gain (>200 cm.sup.-1). The writing of information is reversible. Consequently, the device is suitable for read/write holographic storage and real-time image processing applications, and is capable of being poled at essentially room temperature.Type: GrantFiled: September 10, 1996Date of Patent: April 28, 1998Assignee: Arizona Board of Regents acting for and on behalf of University of ArizonaInventors: Klaus Meerholz, Bernard Kippelen, Nasser N. Peyghambarian, Scott R. Lyon, Henry K. Hall, Jr., Anne B. Padias, (NFN) Sandalphon, Boris L. Volodin