Abstract: An optical microtoroid resonator including one or more nanoparticles attached to a surface of the resonator and capable of receiving an input signal from afar-field source (via free-space transmission) and outputting light propagating within the optical apparatus. A method for coupling light into and out of an optical resonator using a nanoparticle or nanoparticles to interface with spatially separated far-field optical elements.
Type:
Application
Filed:
December 17, 2021
Publication date:
April 7, 2022
Applicant:
Arizona Board of Regents on Behaft of the University of Arizona
Abstract: Systems are provided for assessing the likelihood that a sample of cardiac tissue will spontaneously exhibit disordered electrical activity. These systems induce ventricular tachycardia or other disordered electrical activity in a sample of human and/or animal cardiac tissue either in vivo or in vitro. This system can be used to assess the ability of various pharmaceuticals, genetic modifications, electrical pacing, surgical ablation, or other therapeutic interventions to prevent or halt such disordered electrical activity. This system detects electrical activity from a plurality of points on the surface of the sample of cardiac tissue and generates one or more maps of monophasic action potential amplitude, monophasic action potential duration, local field amplitude, or other electrophysiological parameters of the cardiac tissue.
Type:
Grant
Filed:
July 5, 2018
Date of Patent:
December 8, 2020
Assignee:
THE ARIZONA BOARD OF REGENTS ON BEHAFT OF THE UNIVERSITY OF ARIZONA
Inventors:
Ikeotunye Royal Chinyere, Jen Watson Koevary, Jordan Lancaster, Steven Goldman, Russell Witte, Kyle Weigand