Abstract: Systems are provided for assessing the likelihood that a sample of cardiac tissue will spontaneously exhibit disordered electrical activity. These systems induce ventricular tachycardia or other disordered electrical activity in a sample of human and/or animal cardiac tissue either in vivo or in vitro. This system can be used to assess the ability of various pharmaceuticals, genetic modifications, electrical pacing, surgical ablation, or other therapeutic interventions to prevent or halt such disordered electrical activity. This system detects electrical activity from a plurality of points on the surface of the sample of cardiac tissue and generates one or more maps of monophasic action potential amplitude, monophasic action potential duration, local field amplitude, or other electrophysiological parameters of the cardiac tissue.

Abstract: Methods, apparatus, and systems for the design and use of image guides with a retro-reflector and beam splitter are disclosed. In one example, an apparatus includes: a first image guide situated to propagate a ray bundle so that a first portion exits the image guide output at a first portion angle and a second portion exits the output at a second portion angle opposite the first portion angle, a retro-reflector situated to reflect the respective ray bundle portions along their respective propagation paths incident onto the retro-reflector; a beam splitter situated to receive the reflected ray bundle portions from the retro-reflector, and a second image guide situated to receive the first and second ray bundle portions reflected from the beam splitter plane. In some examples, the retro-reflector is a micro retro-reflector array. In some examples, the retro-reflector is a pseudo-phase conjugate or phase conjugate mirror.

Abstract: The present invention provides methods and systems for 3D imaging of in vivo and ex vivo tissues. The disclosed systems and methods employ an autoradiographic approach where particles emitted by a radioactive composition within the tissue are detected. Once detected, a 3D representation of the source of particles within the tissue is reconstructed for viewing and analysis.

Abstract: The present invention provides a system and a method for detecting or determining a possible fraudulent information provided by a subject using the subject's behavioral biometric during an application filing process using an electronic input device.

Abstract: An apparatus and method of image reconstruction are disclosed. The method includes first breaking a holographic image into a plurality of interlaced sample sets corresponding to color separation images; and independently sampling, filtering, and reconstructing all sets. The resulting demodulated images contain no fringes. Notably, range-clipped tonal rendering curves are used to choose pixel regions of the demodulated images that will replace saturated regions. The image is reconstructed by integrating all un-saturated images into one.