Abstract: The invention provides methods for identifying cell binding and/or lytic polypeptides that permit production of specific polypeptide therapeutics in a high throughput manner.

Abstract: A CO2 detection chamber includes a gas inlet and a gas outlet. A CO2 sensor is housed in the CO2 detection chamber, where the sensor includes a reversible and selective pH-sensitive nanocomposite sensor element for CO2 detection, and a hydrophobic surface. A flowmeter, a thermistor and a humidity sensor operate to read flow and compensate for humidity conditions. A light source is coupled to receive signals from the CO2 sensor and respond to color changes in the sensor by transducing the color change into a light intensity change. A photodiode receives signals from the light source and responds to light intensity changes by transducing the light intensity changes into electronic signals representing varying degrees of light intensity. Data representing CO2 measurements is transmitted for display to a mobile device.

Abstract: A method for characterizing the power consumption of a data center includes the steps of measuring one or more power consumption parameters associated with the data center when no workload is present, generating one or more workloads in the data center in which one or more three phase PDUs include an imbalanced phase, measuring one or more power consumption parameters associated with the data center during the one or more generated workflows, and characterizing the power consumption of the data center due to phase imbalance of the one or more three phase PDUs based on the measurements. By characterizing the power consumption of the data center due to phase imbalance based on empirical measurements, an accurate characterization of the power consumption attributable to phase imbalance can be achieved.

Abstract: The present invention provides for separation of bacterial species and serotypes using electrophoretic methods.

Abstract: A pH treatment and method for extraction of leachable resources and pollutants from sludge. A volume of wastewater sludge is initially dewatered followed by adding pH adjusting agents to the dewatered sludge to remove acid/base-soluble contaminants. The acid/base-soluble contaminants are flushed out or dewatered from the treated product. Treated sludge can then be sent to storage and held for beneficial uses.

Abstract: Threshold logic elements and methods of operating the same are disclosed. In one embodiment, a threshold logic element includes a first input gate network configured to receive a first set of logical signals, a second input gate network configured to receive a second set of logical signals. The differential sense amplifier is operably associated with the first input gate network and the second input gate network such that the differential sense amplifier is configured to generate a differential logical output in accordance with a threshold logic function. In order to make the threshold logic element more robust, the differential sense amplifier is configured to feed back the differential logical output to the first input gate network and the second input gate network. By providing the differential logical output as feedback, floating node issues are avoided and the threshold logic element is more resistant to noise.

Abstract: Methods and compositions for replication of threose nucleic acids (TNAs) are described. The described methods include a method for transcribing a DNA template into a TNA, and a method for reverse transcribing a threose nucleic acid into a cDNA.

Abstract: This disclosure relates generally to resistive memory systems. The resistive memory systems may be utilized to implement neuro-inspired learning algorithms with full parallelism. In one embodiment, a resistive memory system includes a cross point resistive network and switchable paths. The cross point resistive network includes variable resistive elements and conductive lines. The conductive lines are coupled to the variable resistive elements such that the conductive lines and the variable resistive elements form the cross point resistive network. The switchable paths are connected to the conductive lines so that the switchable paths are operable to selectively interconnect groups of the conductive lines such that subsets of the variable resistive elements each provide a combined variable conductance. With multiple resistive elements in the subsets, process variations in the conductances of the resistive elements average out.

Abstract: A surface-emitting semiconductor laser system contains at least one MQW unit of at least three constituent QWs, separated along the optical axis by a sub-wavelength distance. The MQW unit is located within the axial extent covered, in operation of the laser, by a half-cycle of the standing wave of the field at a wavelength within the gain spectrum of the gain medium; immediately neighboring nodes of the standing wave are on opposite sides of the MQW unit. So-configured MQW unit can be repeated multiple times and/or complemented with individual QWs disposed outside of the half-cycle of the standing wave with which such MQW unit is associated. The semiconductor laser further includes a pump source configured to input energy in the semiconductor gain medium and a mode-locking element to initiate mode-locking.

Abstract: This disclosure relates generally to radiation hardened digital circuits. In one embodiment, a radiation hardened digital circuit includes a delay network and a first Muller C element. The delay network is configured to generate a first delayed clock signal from a global clock signal such that that the first delayed clock signal is delayed with respect to the global clock signal. The first Muller C element is configured to generate a first clock input signal and set the first clock input signal to one of a set of clock states in response to the first delayed clock signal and the global clock signal each being provided in a same one of the set of clock states and is configured to hold the first clock input signal otherwise. Thus, a radiation strike is prevented from causing a soft error in the first clock input signal.

Abstract: Embodiments of model-based system design with model verification are disclosed. An embodiment includes receiving a model for a system and at least one specification for the system. In some embodiments, the system determines at least one of a minimum expected robustness value and a maximum expected robustness value for a region of a search space of the model with respect to the at least one specification. The model may be modified based on the determined minimum or maximum expected robust ness value.

Abstract: Triazabutadiene molecules that provide adhesive functionality, e.g., triazabutadiene molecules as underwater adhesives or water-reactive adhesives. The triazabutadiene molecules mask an aryl diazonium ion, a highly reactive chemical functionality. Once unmasked, e.g., in water, the diazonium species is adapted to react with an electron rich aryl ring that can undergo diazonium chemistry (e.g., phenol species, resorcinol species, etc.). Triazabutadienes can be used as additives in adhesive systems such as but not limited to epoxy adhesive systems.

Abstract: Some embodiments include a distributed estimation system. Other embodiments of related systems and methods are also disclosed.

Abstract: A system for optimizing energy efficiency of an embedded system. A hardware abstraction layer (HAL) is coupled to hardware of an embedded system. An energy hardware abstraction layer (eHAL) couples to the hardware and to the HAL. A hypervisor couples to the HAL and to the eHAL. One or more applications couple to the hypervisor, the HAL and the eHAL. The eHAL measures energy use of the embedded system, constructs a model of energy use of the embedded system and, using the model, determines how to one of reduce and minimize energy use of the embedded system. The hypervisor is configured to alter one or more hardware parameters to one of reduce and minimize energy use of the embedded system as the embedded system performs one or more tasks. In implementations a real time operating system (RTOS) is coupled to the one or more applications and to the hypervisor.

Abstract: Systems and methods for managing electricity of an electrical supply grid electrically connected to a wind farm are disclosed. Some systems and methods may include identifying relationships among a plurality of turbines in the wind farm with a minimum spanning tree, calculating a power output relationship among the plurality of turbines with the minimum spanning tree, creating a finite state space Markov chain forecast model for the plurality of turbines in the wind farm, predicting a power output of the wind farm with the finite state space Markov chain forecast model, and modifying at least one of a generation of electricity and a distribution of electricity based on the predicted power output of the wind farm. Also disclosed are systems and methods for predicting the power output of a wind farm.

Abstract: Biomedical devices and methods are disclosed for the development of 3D polymeric scaffolds for cell culture, high throughput screens for biomolecule purification, and generation of bone mimetic materials. The devices may feature multiple geometries, and scaffold generation capabilities include multiple gel types utilizing organic and aqueous phase pregel. Additionally, macroporous and non-macroporous morphologies are possible.

Abstract: Chemical linkage reagents, methods of making and method of using the same are provided. Chemical linkage reagents according to at least some of the embodiments of the present disclosure may be incorporated into or operatively-linked with affinity molecules for attachment to silicon oxide surfaces to, for example, measure interactions between an affinity molecule and its targeting biomolecules.

Abstract: Optical switch based on a micro-mirror device such as a DMD for simultaneous switching light from N inputs to M outputs with switching times of about 10 microseconds, where N and M are generally greater than one. The mirrors of the device are oriented according to a pattern calculated based on a Fourier Transform of spatial distribution of M outputs such as to form, in diffraction of light incident on the device, an diffraction light pattern that in the output plane is substantially congruent with the spatial distribution of M outputs. The device can be configured as a modulator of amplitude and/or a modulator of phase of incident light wavefront.

Abstract: Methods, systems, and media for generating and/or analyzing medical images having elongated structures are provided. In some embodiments, a method for analyzing medical images is provided, the method comprising: receiving a plurality of images, wherein each of the plurality of images includes a portion of an elongated structure; receiving a location of interest within a least one of the plurality of images; determining an orientation of the elongated structure in response to receiving the location of interest; adjusting image planes of each of the plurality of images to correspond with the orientation of the elongated structure; and causing the elongated structure to be displayed in the adjusted image planes.

Abstract: A system for providing neurostimulation includes an external device (“external exciter”) and an implanted device. The external exciter includes an energy source which inductively powers the implanted device. Examples of such external exciters include devices having at least one of: ultrasonic transducers, Radio Frequency (RF) transmitters, and solar cells. The implanted device includes circuitry that limits its maximum energy output to a predetermined saturation threshold such that excess stimulation from the external exciter does not raise the output of the implanted device beyond the saturation threshold. The output signal of the external exciter is then pulse-width modulated in order to produce a desired amount of output stimulation from the implanted device to stimulate the bioelectrically excitable tissue at a desired level.