Patents Assigned to The Australian National University
  • Patent number: 11896683
    Abstract: The invention relates to a radiolabelled material comprising a polymer, a radioactive isotope, and an immobilizing agent, wherein the immobilizing agent is capable of immobilizing the radioactive isotope on or in the polymer, and wherein the immobilizing agent is a macromolecule comprising a polycation with multiple pendant metal-chelating side-chains. The invention also relates to a process for making a radiolabelled material, to use of a radiolabelled material for the preparation of medicaments for treating cancer and/or for radiation imaging and to use of a radiolabelled material in the treatment of cancer. There is further described use of an immobilizing agent to immobilize a radioactive isotope on or in a polymer.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: February 13, 2024
    Assignee: THE AUSTRALIAN NATIONAL UNIVERSITY
    Inventors: Ross Wentworth Stephens, Gregory David Tredwell, Karen Joanne Knox, Lee Andrew Philip, Rebecca Greenlees, Keira Beattie
  • Patent number: 11898962
    Abstract: A method and system for determining a location of artefacts and/or inclusions in a gemstone, mineral or sample thereof, the method comprising the steps of: surface mapping a gemstone, mineral or sample thereof to determine surface geometry associated with at least a portion of a surface of the gemstone, mineral or sample thereof; sub-surface mapping the gemstone, mineral or sample thereof using an optical beam that is directed at the surface along an optical beam path, wherein the optical beam is generated by an optical source using an optical tomography process; determining a surface normal at the surface at an intersection point between the optical beam path and the determined surface geometry; determining relative positioning between the surface normal and the optical beam path; and determining the location of artefacts and/or inclusions in the gemstone, mineral or sample thereof based on the sub-surface mapping step and the determined relative positioning.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: February 13, 2024
    Assignee: The Australian National University
    Inventors: Roland Fleddermann, Jong Hann Chow, Adrian Paul Sheppard, Timothy John Senden, Shane Jamie Latham, Keshu Huang
  • Publication number: 20230255992
    Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of extracellular histones in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating extracellular histone mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRO). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of extracellular histone mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g.
    Type: Application
    Filed: February 6, 2023
    Publication date: August 17, 2023
    Applicants: The Australian National University, Griffith University
    Inventors: Christopher Parish, Connor O'Meara, Lucy Coupland, Benjamin Ju Chye Quah, Farzaneh Kordbacheh, Anna Orlov, Anna Browne, Ross Stephens, Gregory David Tredwell, Lee Andrew Philip, Karen Knox, Laurence Mark von Itzstein, Chih-Wei Chang, Anne Brüstle, David Anak Simon Davis
  • Patent number: 11628179
    Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of extracellular histones in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating extracellular histone mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRI)). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of extracellular histone mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g., mCBS.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: April 18, 2023
    Assignees: The Australian National University, Griffith University
    Inventors: Christopher Parish, Connor O'Meara, Lucy Coupland, Benjamin Ju Chye Quah, Farzaneh Kordbacheh, Anna Orlov, Anna Browne, Ross Stephens, Gregory David Tredwell, Lee Andrew Philip, Karen Knox, Laurence Mark von Itzstein, Chih-Wei Chang, Anne Brüstle, David Anak Simon Davis
  • Patent number: 11566148
    Abstract: The invention relates to a film comprising an interpenetrating network, its uses and processes for making the same. The film produced displays good durability, chemical resistance and transparency. The film is produced from an interpenetrating network formed as a colloidal suspension in an organic solvent and a particulate solid.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: January 31, 2023
    Assignee: THE AUSTRALIAN NATIONAL UNIVERSITY
    Inventors: William Sai Yau Nong, Antonio Tricoli, David Russell Nisbet, Zbigniew Stachurski
  • Patent number: 11542267
    Abstract: Disclosed herein is a method for coupling a first compound having the formula (I) with a second compound that contains a carbonyl group. Also disclosed herein are compounds that can be formed by this method, and uses for such compounds.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: January 3, 2023
    Assignees: Australian Nuclear Science and Technology Organisation, The Australian National University
    Inventors: Suzanne Virginia Smith, Eskender Mume, Gary James Perkins
  • Patent number: 11535623
    Abstract: Disclosed herein is a method for coupling a first compound having the formula (I) with a second compound that contains a carbonyl group. Also disclosed herein are compounds that can be formed by this method, and uses for such compounds.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: December 27, 2022
    Assignees: Australian Nuclear Science and Technology Organisation, The Australian National University
    Inventors: Suzanne Virginia Smith, Eskender Mume, Gary James Perkins
  • Patent number: 11449985
    Abstract: A system includes an imager, a processor, and an output module. The imager is configured to provide a plurality of tissue images. The processor is coupled to the imager and is configured to receive the plurality of images. The processor is coupled to a memory. The memory has instructions for determining classification of a region of tissue associated with the plurality of tissue images. Determining classification includes fusing discriminator outputs from a region covariance descriptor and from a normalized color histogram discriminator. The output module is coupled to the processor. The output module is configured to provide a three dimensional representation of the tissue.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: September 20, 2022
    Assignees: Regents of the University of Minnesota, Australian National University
    Inventors: Panagiotis Stanitsas, Anoop Cherian, Vassilios Morellas, Nikolaos Papanikolopoulos, Alexander Truskinovsky
  • Patent number: 11137663
    Abstract: A frequency conversion device, including a source of a pump beam of electromagnetic radiation of a first wavelength, and an array of mutually spaced semiconductor islands including at least one III-V semiconductor compound and configured so that the pump beam of electromagnetic radiation of the first wavelength incident upon the semiconductor islands and electromagnetic radiation of a second wavelength incident upon the semiconductor islands cause the semiconductor islands to emit electromagnetic radiation of a third wavelength different to the first and second wavelengths by at least one of a sum frequency generation process and a difference frequency generation process, wherein the semiconductor islands are supported by a transparent support such that the support is substantially transparent to radiation of the third wavelength, wherein at least the radiation of the third wavelength passes through the transparent support.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: October 5, 2021
    Assignee: The Australian National University
    Inventors: Dragomir N. Neshev, Mohsen Rahmani, Hark Hoe Tan, Chennupati Jagadish, Yuri Kivshar, Fouad Karouta, Alexander Solntsev, Lei Xu, Giuseppe Marino, Andrey Sukhorukov
  • Patent number: 11015838
    Abstract: A bladed solar thermal receiver for absorbing concentrated sunlight is disclosed. The receiver includes a plurality of panels arranged in a bladed configuration for absorbing sunlight. The bladed configurations can be radial or planar. The receiver design increases the effective solar absorptance and efficiency by providing a light trap for the incident solar radiation while reducing heat losses from radiation and convection.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: May 25, 2021
    Assignees: National Technology & Engineering Solutions of Sandia, LLC, Australian National University
    Inventors: Clifford K. Ho, Joshua Mark Christian, John Downing Pye
  • Patent number: 10935281
    Abstract: Solar receivers including a plurality of multi-scale solar absorbing surfaces arranged such that light or heat reflected from or emitted from one or more of the plurality of solar absorbing surfaces impinges one or more other solar absorbing surfaces of the solar receiver. The disclosed receivers increase the amount of absorbed energy from a concentrated light source, such as a heliostat field, and reduce radiative and convective heat losses.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: March 2, 2021
    Assignees: National Technology & Engineering Solutions of Sandia, LLC, The Australian National University
    Inventors: Clifford K. Ho, Joshua Mark Christian, John Downing Pye, Jesus Daniel Ortega
  • Publication number: 20210041369
    Abstract: A method and system for determining a location of artefacts and/or inclusions in a gemstone, mineral or sample thereof, the method comprising the steps of: surface mapping a gemstone, mineral or sample thereof to determine surface geometry associated with at least a portion of a surface of the gemstone, mineral or sample thereof; sub-surface mapping the gemstone, mineral or sample thereof using an optical beam that is directed at the surface along an optical beam path, wherein the optical beam is generated by an optical source using an optical tomography process; determining a surface normal at the surface at an intersection point between the optical beam path and the determined surface geometry; determining relative positioning between the surface normal and the optical beam path; and determining the location of artefacts and/or inclusions in the gemstone, mineral or sample thereof based on the sub-surface mapping step and the determined relative positioning.
    Type: Application
    Filed: March 4, 2019
    Publication date: February 11, 2021
    Applicant: The Australian National University
    Inventors: Roland Fleddermann, Jong Hann Chow, Adrian Paul Sheppard, Timothy John Senden, Shane Jamie Latham, Keshu Huang
  • Patent number: 10717741
    Abstract: Disclosed herein is a method for coupling a first compound having the formula (I) with a second compound that contains a carbonyl group. Also disclosed herein are compounds that can be formed by this method, and uses for such compounds.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: July 21, 2020
    Assignees: Australian Nuclear Science and Technology Organisation, The Australian National University
    Inventors: Suzanne Virginia Smith, Eskender Mume, Gary James Perkins
  • Patent number: 10698293
    Abstract: A frequency conversion device and method is disclosed. In one aspect, a frequency device includes an array of mutually spaced semiconductor islands composed of at least one III-V semiconductor compound. The semiconductor islands are configured so that electromagnetic radiation of a first wavelength incident upon the semiconductor islands causes them to emit electromagnetic radiation of a second wavelength shorter than the first wavelength by a nonlinear frequency conversion process. The frequency device further includes a transparent support supporting the semiconductor islands. The transparent support is substantially transparent to radiation of the second wavelength, so that at least the radiation of the second wavelength passes through the transparent support.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: June 30, 2020
    Assignee: The Australian National University
    Inventors: Mohsen Rahmani, Dragomir N. Neshev, Hark Hoe Tan, Chennupati Jagadish, Yuri Kivshar, Fouad Karouta
  • Patent number: 10636397
    Abstract: A stand for a musical instrument, the stand comprising: a base; an upright having an upper end and extending upwardly from the base to the upper end; a member comprising a first end portion and a second end portion, the member being mounted on the upper end of the upright between the first end portion and the second end portion; an attachment fitting mounted on the first end portion and configured to releasably attach the musical instrument; and a counterweight mounted on the second end portion for balancing the weight of the musical instrument.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: April 28, 2020
    Assignee: THE AUSTRALIAN NATIONAL UNIVERSITY
    Inventors: John Albert Mackey, Stephen Murray Holgate
  • Patent number: 10507236
    Abstract: The present invention is directed generally to chimeric proteins that can facilitate targeting of nanoparticulate carriers to antigen presenting cells, and to nanoparticulate carriers comprising these chimeric proteins. The invention is also directed to methods of internalizing an antigen in an antigen presenting cell, and methods of eliciting an immune response to an antigen in a subject, using the nanoparticulate carriers comprising the chimeric proteins.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: December 17, 2019
    Assignees: Lipotek Pty Ltd, The Australian National University
    Inventors: Jason David Price, Christopher Parish, Ines Atmosukarto
  • Patent number: 10500812
    Abstract: The present invention provides a film for attaching a nanostructured material to a surface of a substrate, comprising: (a) a removable support; (b) an attaching layer for attaching the film to the surface of a substrate; and (c) the material directly coupled to the support and the attaching layer. Methods for making the film, methods for attaching the material to the surface of a substrate are also provided. The present invention further provides a surface having a material attached thereto by means of the attaching layer. Using the methods disclosed herein, a material having a high specific surface area (SSA) and having particular proper ties (e.g. super-hydrophobicity) can be applied to a substrate including a fuel cell, a conductive electrode, a dye sensitized solar cell, a diffuse reflective mirror, eyewear, a window and a vehicle (e.g. car) windscreen, for example to provide a self-cleaning surface.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: December 10, 2019
    Assignee: The Australian National University
    Inventors: Antonio Tricoli, David Russell Nisbet
  • Publication number: 20190327974
    Abstract: This invention is directed to synergists for organophosphate (OP), carbamate (CM) and/or pyrethroid/synthetic pesticides (SP). This invention is further directed to a composition comprising organophosphate, carbamate, and/or pyrethroid/synthetic pyrethroid, and at least one boronic acid derivative. This invention further provides methods for killing insect pests.
    Type: Application
    Filed: January 9, 2018
    Publication date: October 31, 2019
    Applicants: THE AUSTRALIAN NATIONAL UNIVERSITY, YEDA RESEARCH AND DEVELOPMENT CO. LTD., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Colin JACKSON, Nir LONDON, Galen CORREY, Janelle SAN JUAN
  • Patent number: 10428336
    Abstract: The present invention provides a method for modulating non-root plant growth of a plant employing plant regulatory peptides, nucleotides encoding same, receptors therefor, binding agents thereof or agonists or antagonists thereof. Such methods encompass methods for increasing shoot growth or accelerating shoot development of plants, whereby said plants: yield a greater amount of above-ground plant matter than an untreated or wild-type plant grown under the same conditions; grows faster than an untreated or wild-type plant grown under tire same conditions; develops faster than an untreated or wild-type plant grown under the same conditions. The methods find particular application, wherein the conditions comprise stress conditions, and in particular abiotic stress conditions, which may be selected from increased salinity, drought, nitrogen limitation and pH stress.
    Type: Grant
    Filed: October 16, 2014
    Date of Patent: October 1, 2019
    Assignee: The Australian National University
    Inventors: Michael Djordjevic, Nijat Imin, Christina Delay
  • Patent number: 10416216
    Abstract: This disclosure concerns photonics and in particular the addressing of individual targets in solids. In aspect one there is provided a device comprising a solid substrate with one or more atomic scale targets in the substrate. A laser light is focused on a region of the substrate that contains a single target to selectively cause photoionization of the target. A charge sensor with sub-electron charge sensitivity is focussed on measuring the charge in the region of the substrate that contains a single target. In use, the device operates such that the laser is turned on to cause photoionization of the target, and the charge sensor detects the change in charge in the region of the substrate that contains the single target. In another aspect is the method for optically investigating individual nuclear spin states of single atoms by investigating both the Zeeman effect and the hyperfine interaction of the single atoms.
    Type: Grant
    Filed: December 11, 2013
    Date of Patent: September 17, 2019
    Assignees: Australian National University
    Inventors: Sven Rogge, Matthew John Sellars, Chunming Yin, Jeffrey Colin McCallum, Gabriele Gaetano De Boo, Milos Rancic, Nikolas Stavrias