Abstract: A method for analysis of blood components or parameters is disclosed where a probe having an excitation outlet and a response inlet is placed in proximity to or in contact with a tissue of an underside of a patient's tongue over a big vein in the tongue so that an excitation signal exits the outlet, produces a response which enters the inlet for detection and analysis.

Abstract: The present invention provides methods for detecting, analyzing, and identifying biomolecules used to identifying patient with dengue-like symptom who are at risk of DHF. The inventive method comprises detecting in a sample from a subject dengue infected patient one or more biomarkers selected from the group consisting of IL-10, fibrinogen, C4A, immunoglobulin, tropomyosin, and three isoforms of albumin, and which are used in a predictive MARS model to detect patients with risk of developing DHF.

Abstract: The present invention relates to the identification of miRNAs that are involved in cardiac remodeling following ischemia and ischemia reperfusion injury. A subset of these miRNAs are regulated in the short term following an ischemic event indicating that these miRNAs play an important role in the induction of subsequent pathological events. Modulation of these identified miRNAs as a treatment or prevention for myocardial ischemia and ischemia reperfusion injury is described.

Abstract: An arm movement restraining and permission cord apparatus is disclosed for patients receiving cardiac pacemakers and similar implants to prevent patients for arm movements that may result in health risk due to leads being pulled out from the heart muscle.

Abstract: Provided herein are methods for ameliorating the pathophysiology cysteine protease exotoxin comprising the step of administering to said individual an effective dose of an S-nitrosylating agent and an inositol phosphate or analog thereof.

Abstract: The present invention relates to the field of immunology and hyperproliferative diseases. More specifically, the present invention relates to a method of detecting and monitoring therapeutic antibody:antigen complex, soluble antigen and soluble therapeutic antibody, wherein a patient has undergone at least one course of immunotherapy. Yet further, levels of therapeutic antibody:antigen complexes, soluble antigens or soluble therapeutic antibodies may be measured and used to stage or monitor a hyperproliferative disease.

Abstract: The invention generally relates to molecular diagnostics, and particularly to molecular markers for cancer therapy response and methods of use thereof.

Abstract: A method of preparing a population of in vitro cultured cells of alveolar epithelial type II (ATII) cell lineage derived from at least one embryonic stem cell is disclosed which comprises (a) culturing said at least one embryonic stem cell in vitro in a medium comprising MATRIGEL®, to produce differentiated cells without formation of an embryonic body, wherein at least some of the differentiated cells are of ATII cell phenotype; (b) identifying the differentiated cells of ATII cell phenotype by detecting expression of at least one biomarker of ATII cells; (c) isolating the differentiated cells having ATII cell phenotype; and (d) cloning the isolated cells to produce a population of cells having ATII cell phenotype. The resulting cells are preferably >99% pure ATII phenotype lineage and are potentially useful therapeutically for treating lung injury and disease.

Abstract: The present invention discloses a chimeric Chikungunya virus comprising a heterologous alphavirus cDNA fragment and a Chikungunya virus cDNA fragment. The heterologous alphavirus may include but is not limited to Sindbis virus, Eastern equine encephalitis virus or Venezuelan equine encephalitis virus. The present invention also discloses the use of this chimeric Chikungunya virus as vaccines and in serological and diagnostic assays.

Abstract: A sensor, sensor assembly and a method of sensing, in which the sensor is in contact with a material or structure and the sensor directly measures one or more property changes in the material by means of light reflection and scattering using a reflective target.

Abstract: In accordance with one or more embodiments of the present disclosure a method for forecasting an advanced recovery process for a reservoir comprises determining a displacement Koval factor associated with a displacement agent associated with an advanced recovery process. The displacement Koval factor is based on heterogeneity of porosity of the reservoir and mobility of the displacement agent. The method further comprises determining a final average oil saturation of the reservoir associated with the advanced recovery process being finished. The method additionally comprises determining an average oil saturation of the reservoir as a function of time for the advanced recovery process based on the displacement Koval factor and the final average oil saturation.

Abstract: A system for wireless power transmission may include one or more charging panels and one or more powered devices. The charging panel may include a pilot analysis circuitry, processor and power transmitter. The pilot analysis circuitry may be configured to analyze the magnitude and phase of a pilot signal from the powered device, based on which the processor may be configured to determine a complex conjugate of the pilot signal. And the power transmitter may be configured to cause radiation of a focused wireless power beam to the powered device in accordance with the complex conjugate of the pilot signal and via one or more antenna elements. The charging panel may be one of a plurality of spatially-distributed charging panels each of which includes respective antenna elements that may form an array of antenna elements configured to collaboratively radiate wireless power as a distributed, retro-reflective beamformer.

Abstract: The present invention includes a polymer formed by the thermal rearrangement of an ortho-functional polyimide synthesized via chemical imidization with permeation properties for gas separation membranes higher than those synthesized via thermal imidization and a method for forming that polymer having tailored transport properties and different chemical resistance. The present invention also includes a polymer formed by the thermal rearrangement of an ortho-functional polyimide in which a portion of the ortho-position functional group is lost during thermal rearrangement to yield a thermally rearranged polymer with higher permeability than would be seen without the ortho-position group. This ortho-position group can be the result of chemical imidization, or the result of a post-imidization modification reaction.

Abstract: An assay and associated methodologies for detection of breast cancer are described. Circulating tumor cells (“CTCs”) undergo epithelial mesenchymal transition (“EMT”) prior to entering circulation, resulting in the loss of epithelial markers. These CTCs and EMT-related gene transcripts in the peripheral blood of patients are tested by quantitative RT-PCR to detect and diagnose breast cancer.

Abstract: In a method and system to fabricate a compact optical device, a periodic group-delay device (PGDD) includes N optical input ports, N being a positive integer number, each port being configured to include one or more wavelength-division-multiplexing (WDM) channels; N corresponding optical output ports, each port being configured to include one or more WDM channels. The PGDD also includes a first slab waveguide region (FSWR) coupled to the N optical input ports, a second slab waveguide region (SSWR) coupled to the said N optical output ports, a first optical grating coupled to the FSWR, a second optical grating coupled to the SSWR, and; a third slab waveguide region (TSWR) coupled to at least one of the first and second optical gratings. The TSWR is configured to provide a configurable amount of dispersion to the N optical output ports. Optical signals carried by each WDM channel are processed concurrently and independently.

Abstract: A nanoparticle-polypeptide complex comprising a bioactive polypeptide in association with a nanoparticle, wherein the bioactive polypeptide is modified by the addition of a chemical moiety that facilitates cellular uptake of the protein. The polypeptide can be a protein or a peptide. In some embodiments, the amino acid sequence of the protein or peptide is derived from the amino acid sequence of a tumor suppressor gene product.

Abstract: Embodiments are directed to compositions and methods related combination therapy with HERV inhibition.

Abstract: Methods of diagnosing tumor susceptibility or cancer including the step of determining whether a patient has one or more SNP-miRNA expression pattern combinations described herein. Each SNP-miRNA expression pattern combination is supported by data that shows that the SNP is associated with tumor susceptibility because of its ability to affect miRNA binding sites and/or miRNA:mRNA gene regulation.

Abstract: Chiral thioureas are effective catalysts for the borane reduction of prochiral ketones to optically active alcohols. A prochiral ketone may be reduced to an optically active alcohol in the presence of a substantially sub-stoichiometric amount of chiral thiourea. The asymmetric thiourea compound of the present invention may be produced according to a production method described herein.

Abstract: Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.