Abstract: Methods are described for slowing or inhibiting the progression of heart failure in a mammalian subject suffering from chronic hypertension. The methods involve administering an ?PKC, ?1PKC, or ?IIPKC peptide inhibitor, examples of which are provided.
Type:
Grant
Filed:
June 1, 2007
Date of Patent:
June 22, 2010
Assignee:
The Board of Trustee of The Leland Stanford Juinior University
Inventors:
Daria D. Mochly-Rosen, Koichi K. Inagaki