Abstract: A method for controlling weight by suppressing the normal metabolism of adipose tissue is disclosed. Administration of tumor necrosis factor (TNF) or a pharmaceutical composition containing it results in suppression of anabolism of adipose cells.
Type:
Grant
Filed:
November 26, 1985
Date of Patent:
August 4, 1987
Assignees:
The Board of Trustees of the Cetus Corporation, Leland Stanford Junior University
Inventors:
James W. Larrick, Gordon M. Ringold, David F. Mark, Leo S. Lin, Frank M. Torti