Abstract: Methods and compositions for at least determining whether a human subject has a pancreatic disease are provided. In practicing the subject methods, a sample from a subject is assayed for a pancreatic glycoprotein (GP2) analyte to determine whether the subject at least has the pancreatic disease. Also provided are kits, systems, and devices for practicing the subject methods.

Abstract: A source of coherent blue light comprises a diode laser for pumping a Nd.sup.3+ doped member of lasant material disposed within an optical resonator for exciting the .sup.4 F.sub.3/2 -.sup.4 I.sub.9/2 laser transition of a wavelength within the range of 0.870 to 0.960 .mu.m. The laser radiation within the optical resonator is doubled by means of a doubler crystal of a non-linear, electro-optic material to produce blue light which is then extracted from the optical resonator as an output beam. A thermo-electric cooler is coupled in heat-exchanging relation with the Nd.sup.3+ doped laser material to improve the efficiency and the doubler crystal is temperature controlled for phase matching to the laser radiation within the range of 0.870 to 0.960 .mu.m. The diode pump laser is preferably either a GaAlAs or GaAs diode laser producing pumping radiation of a wavelength of approximately 0.810 .mu.m.