Patents Assigned to The Board of Trustees of the Leland Stanford Juniot University
  • Method of controlling the degradation of glycoprotein oligosaccharides produced by cultured Chinese hamster ovary cells
    Patent number: 5510261
    Abstract: A neuraminidase enzyme with unusually high activity under extracellular culture conditions has been discovered in Chinese hamster ovary (CHO) cells and other types of cells. By affecting the neuraminidase activity of the cell culture, the degradation of glycoprotein oligosaccharides produced by these cultured cells can be controlled.
    Type: Grant
    Filed: January 12, 1995
    Date of Patent: April 23, 1996
    Assignee: The Board of Trustees of the Leland Stanford Juniot University
    Inventors: Charles F. Goochee, Michael J. Gramer