Abstract: Nick-based methods, devices, and systems for nick-based data storage in a deoxyribonucleic acid (DNA) sequence are disclosed. Digital information is encoded in a register of at least one copy of a double-stranded DNA sequence having a plurality of nickable positions. The data is translated into a sequence of values from a nick alphabet that is subsequently mapped to the plurality of nickable positions, and the DNA sequence is nicked according to the mapped values. Because the digital information is encoded as a series of nicked and non-nicked positions of a double-stranded DNA sequence, the nucleotide sequence of the DNA can be non-synthetic, or “native” DNA.
Type:
Grant
Filed:
September 19, 2018
Date of Patent:
December 27, 2022
Assignee:
THE BOARD OF TRUSTEES OF THE
UNIV OF ILLINOIS
Abstract: A method for reducing arrhythmic risk associated with cardiomyopathy includes administering a composition containing NAD+ or a mitochondrial targeted antioxidant to an individual in need thereof.
Type:
Grant
Filed:
July 18, 2012
Date of Patent:
December 29, 2015
Assignees:
U.S. DEPARTMENT OF VETERANS AFFAIRS, THE BOARD OF TRUSTEES OF THE UNIV. OF ILLINOIS
Abstract: A method for reducing arrhythmic risk associated with cardiomyopathy by improving conduction velocity, includes administering a composition containing NAD+ or a mitochondrial targeted antioxidant to an individual or person in need thereof.
Type:
Grant
Filed:
August 14, 2012
Date of Patent:
December 15, 2015
Assignees:
U.S. DEPARTMENT OF VETERANS AFFAIRS, THE BOARD OF TRUSTEES OF THE UNIV. OF ILLINOIS
Abstract: A method of treating, preventing, reversing, or ameliorating diastolic dysfunction includes reducing S-glutathionylated myosin binding protein-C (MyBP-C) level by administering to a host in need thereof a therapeutically effective amount of tetrahydrobiopterin (BH4).
Type:
Grant
Filed:
October 24, 2012
Date of Patent:
August 25, 2015
Assignees:
U.S. DEPT. OF VETERANS AFFAIRS, THE BOARD OF TRUSTEES OF THE UNIV. OF ILLINOIS
Abstract: Method for modulating or controlling sodium channel current of a cell includes inducing mitochondrial reactive oxygen species (ROS) production in the cell.
Type:
Grant
Filed:
February 16, 2011
Date of Patent:
August 25, 2015
Assignees:
THE UNITED STATES OF AMERICA DEPT. OF VETERANS AFFAIRS, THE BOARD OF TRUSTEES OF THE UNIV. OF ILLINOIS
Abstract: A method of modulating or controlling connexin 43 (Cx43) level of a cell includes inducing mitochondrial reactive oxygen species (ROS) production in the cell.
Type:
Grant
Filed:
June 21, 2012
Date of Patent:
June 9, 2015
Assignees:
U.S. DEPARTMENT OF VETERANS AFFAIRS, THE BOARD OF TRUSTEES OF THE UNIV. OF ILLINOIS
Abstract: An exemplary fuel cell of the invention includes a formic acid fuel solution in communication with an anode (12, 134), an oxidizer in communication with a cathode (16, 135) electrically linked to the anode, and an anode catalyst that includes Pd. An exemplary formic acid fuel cell membrane electrode assembly (130) includes a proton-conducting membrane (131) having opposing first (132) and second surfaces (133), a cathode catalyst on the second membrane surface, and an anode catalyst including Pd on the first surface.
Type:
Application
Filed:
November 5, 2004
Publication date:
May 3, 2007
Applicant:
THE BOARD OF TRUSTEES OF THE UNIV. OF ILLINOIS
Abstract: A method for obtaining starch from maize involving soaking maize kernels in water to produce soaked maize kernels, grinding the soaked maize kernels to produce a ground maize slurry, and incubating the ground maize slurry with enzyme (e.g., protease).
Type:
Grant
Filed:
May 31, 2001
Date of Patent:
May 20, 2003
Assignees:
The United States of America as represented by the Secretary
of Agriculture, Board of Trustees of the Univ. of Illinois
Inventors:
David B. Johnston, Vijay Singh, Steven Eckhoff
Abstract: A raised on-chip planar inductor. An inductor is fabricated on a substrate. The inductor, except for an anchoring extremity, is lifted from the substrate, preferably by application of a magnetic field to a magnetic layer formed on the inductor. The lifting of the inductor deforms a plastic bending region. After the magnetic field is removed, the inductor remains raised with respect to the substrate.
Type:
Application
Filed:
May 23, 2002
Publication date:
January 2, 2003
Applicant:
The Board of Trustees of the Univ. of Illinois
Abstract: The present invention is directed to organic materials that have the ability to double or triple the frequency of light that is directed through the materials. Particularly, the present invention is directed to the compound 4-[4-(2R)-2-cyano-7-(4'-pentyloxy-4-biphenylcarbonyloxy)phenylheptylidene) phenylcarbonyloxy]benzaldehyde, which can double the frequency of light that is directed through the compound. The invention is also directed to the compound (12-hydroxy-5,7-dodecadiynyl) 4'-[(4'-pentyloxy-4-biphenyl)carbonyloxy]-4-biphenylcarboxylate, and its polymeric form. The polymeric form can triple the frequency of light directed through it.
Type:
Grant
Filed:
January 12, 1994
Date of Patent:
May 2, 1995
Assignee:
The Board of Trustees of the Univ. of Illinois
Inventors:
Samuel I. Stupp, Sehwan Son, Hong-Cheu Lin
Abstract: Insecticidal compositions comprising one or more compounds selected from the group consisting of delta-aminolevulinic acid, inducers of delta aminolevulinic acid, and enhancers of delta-aminolevulinic acid conversion to photodynamic tetrapyrroles; and methods of making and using same.
Type:
Grant
Filed:
January 9, 1989
Date of Patent:
April 6, 1993
Assignee:
The Board of Trustees of the Univ. of Illinois
Inventors:
Constantin A. Rebeiz, John A. Juvik, Carole C. Rebeiz
Abstract: A planar antenna is described which comprises a sandwich like structure of a radiating patch, ground plane and transmission feed line. Capacitive means connect the path to the feed line through a rectangular aperture in the ground plane. The energization of the feed line excites radiating modes in both the aperture and the space between the radiating patch and ground plane thereby resulting in an improved impedance bandwidth.
Type:
Grant
Filed:
September 15, 1987
Date of Patent:
November 20, 1990
Assignee:
Board of Trustees of the Univ. of Illinois