Patents Assigned to The Board of Trustees of the University
  • Patent number: 12384023
    Abstract: Various implementations include a modular soft robot including a base, an arm coupled to the base, and an actuator. The arm includes a first surface and a second surface opposite and spaced apart from the first surface. The first surface defines a plurality of channels, each channel comprising a proximal end at the first surface and a distal end spaced apart from the proximal end. Each channel has a longitudinal axis extending therethrough. The actuator is configured to deform the arm.
    Type: Grant
    Filed: April 20, 2023
    Date of Patent: August 12, 2025
    Assignee: The Board of Trustees of The University of Alabama
    Inventors: Vishesh Vikas, Caitlin Freeman, Michael Maynard
  • Patent number: 12385837
    Abstract: A photon peak event detection system accepts an analog output from a photon sensor, directly digitizes the analogy output and includes a graphics processing unit (GPU) programmed to conduct a photon peak event detection in real-time via a photon count program that analyzes the digitized photon sensor output in sampling periods each having at least three consecutive data points to determine a local maximum among the consecutive data points and compare the local maximum to one or more predetermined thresholds to determine whether or not a photon was received in each sampling period, the algorithm providing photon counts to a phasor analysis program in the GPU. The phasor analysis program calculates pixelwise fluorescence lifetime phasor data in real-time and sends the data to a central processing unit.
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: August 12, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Stephen Boppart, Janet Sorrells, Rishyashring Raman Iyer
  • Publication number: 20250250582
    Abstract: Plant cells, plants, seeds and portions of plants modified or genetically engineered to have increased expression or activity of at least one protein selected from the group consisting of trehalose phosphate synthetase (TPS), trehalose phosphate phosphatase (TPP), Protein ALP1-like (At3g55350 or ALPL1), Glycosyltransferase 75D1 (UGT75D1), Cytochrome P450 709B2 (CYP709B2), Cytochrome P450 709B1 (CYP709B1) and Cytochrome P450 72A15 (CYP72A15) are provided herein. Also provided are methods of increasing plant resistance to herbicides and/or abiotic stress by increasing expression of at least one of trehalose phosphate synthetase (TPS), trehalose phosphate phosphatase (TPP), Protein ALP1-like (At3g55350 or ALPL1), Glycosyltransferase 75D1 (UGT75D1), Cytochrome P450 709B2 (CYP709B2), Cytochrome P450 709B1 (CYP709B1) or Cytochrome P450 72A15 (CYP72A15).
    Type: Application
    Filed: January 3, 2025
    Publication date: August 7, 2025
    Applicant: The Board of Trustees of the University of Arkansas
    Inventors: Christopher E. Rouse, Nilda Roma-Burgos, Gulabben Rangani
  • Patent number: 12378577
    Abstract: The present disclosure relates to CRISPR-Cas10 systems and methods for phage genome editing.
    Type: Grant
    Filed: September 16, 2022
    Date of Patent: August 5, 2025
    Assignee: The Board of Trustees of The University of Alabama
    Inventor: Asma Hatoum
  • Patent number: 12375501
    Abstract: A system and methods to obfuscate encrypted data packets from traffic analysis attacks are disclosed. At a high level, a processing device: executes an application or protocol for receiving traffic associated with the application or protocol; selects an obfuscation interval duration for a next transmission of a data packet; determines, at the obfuscation interval duration, if a queue for transmission of a next data packet associated with the application or protocol is: i) empty, or ii) has a next data packet associated with an application or protocol; and transmits, based on the determination, at least one of: i) a length-adjusted next encrypted data packet, or ii) an encrypted obfuscation data packet. In The transmitted length-adjusted encrypted next data packet can be generated using the next data packet and is adjusted in length with an obfuscation payload prior to encryption and subsequent transmission.
    Type: Grant
    Filed: August 28, 2023
    Date of Patent: July 29, 2025
    Assignees: The Regents of the University of Colorado, a body corporate, The Board of Trustees of the University of Illinois
    Inventors: Alireza Vahid, Jafar Haadi Jafarian, Amirreza Niakanlahiji
  • Patent number: 12371775
    Abstract: Various implementations include a device for deposition of conformal coatings. The device includes a powder container, a connecting rod, and a crankshaft. The powder container has a first side configured to contain a powder and a second side. The connecting rod has a first end directly hingedly coupled to the second side of the powder container and a second end. The crankshaft has a longitudinal axis, a main shaft portion extending along the longitudinal axis, and a cam portion radially offset from and rotatable about the longitudinal axis. The second end of the connecting rod is directly rotatably coupled to the cam portion. Rotation of the crankshaft about the longitudinal axis causes the second end of the connecting rod to rotate about the longitudinal axis, causing the powder container to linearly oscillate between a first position and a second position.
    Type: Grant
    Filed: November 2, 2022
    Date of Patent: July 29, 2025
    Assignee: The Board of Trustees of The University of Alabama
    Inventors: Jonathan Lake Priedeman, Gregory Bruce Thompson
  • Patent number: 12369544
    Abstract: A rice cultivar designated ARoma 22 is disclosed herein. The present invention provides seeds, plants, and plant parts derived from rice cultivar ARoma 22. Further, it provides methods for producing a rice plant by crossing ARoma 22 with itself or another rice variety. The invention also encompasses any rice seeds, plants, and plant parts produced by the methods disclosed herein, including those in which additional traits have been transferred into ARoma 22 through the introduction of a transgene or by breeding ARoma 22 with another rice cultivar.
    Type: Grant
    Filed: October 26, 2022
    Date of Patent: July 29, 2025
    Assignee: The Board of Trustees of the University of Arkansas
    Inventors: Debra Ahrent Wisdom, Karen A. K. Moldenhauer
  • Patent number: 12365816
    Abstract: An adhesive gripper for pick-and-place maneuvers comprises one or more legs, where each leg terminates in a foot rotatably connected to the respective leg. Each foot includes a SMP dry adhesive comprising a shape memory polymer, and a rigid backing layer attached to a back side of the SMP dry adhesive, such that a front side of the SMP dry adhesive is available for attachment and release of objects. The adhesive gripper further includes a handle portion connected to the one or more legs, a release mechanism comprising a release ring within the handle portion, and one or more releasing rods integrated with the one or more legs for release of an object onto a substrate.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: July 22, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Seok Kim, ChangHee Son
  • Publication number: 20250230112
    Abstract: This disclosure relates to processes for converting saturated polyethylene to at least an alkene product. The processes comprise contacting the saturated polyethylene with three or more catalyst components in a reactor, the reactor comprising an alkene reactant. The three or more catalyst components comprise a metathesis catalyst component, an isomerization catalyst component, and a dehydrogenation catalyst component. Contacting causes at least a portion of the saturated polyethylene to undergo dehydrogenation reactions to form unsaturated polyethylene and at least a portion of the unsaturated polyethylene, or products derived therefrom, to undergo metathesis reactions and isomerization reactions to produce an effluent comprising at least the alkene product.
    Type: Application
    Filed: June 14, 2023
    Publication date: July 17, 2025
    Applicants: Dow Global Technologies LLC, The Regents of the University of California, The Board of Trustees of the University of Illinois
    Inventors: Ivan A. Konstantinov, Rafael Huacuja, Alex J. Nett, Mari S. Rosen, Sean W. Ewart, Garrett Strong, Lijun Gao, Nicholas Wang, Vanessa DaSilva, Damien S. Guironnet, Susanna Scott
  • Patent number: 12350399
    Abstract: A hemostatic composition is provided. The hemostatic composition includes a hemostatically effective amount of a hemostatic agent that includes a nanoparticle and a polyphosphate polymer attached to the nanoparticle. Also provided are medical devices and methods of use to promote blood clotting.
    Type: Grant
    Filed: May 31, 2023
    Date of Patent: July 8, 2025
    Assignees: The Regents of the University of California, The Board of Trustees of the University of Illinois
    Inventors: Damien Kudela, Galen D. Stucky, Anna May-Masnou, Gary Bernard Braun, James H. Morrissey, Stephanie A. Smith
  • Patent number: 12346410
    Abstract: Segmentation or other classification of digital pathology images with a deep learning model allows for sophisticated spatial features for cancer diagnosis to be extracted in an automated, fast, and accurate manner. A tiered analysis of tissue structure based in part on deep learning methods is provided. First, tissues depicted in a digital pathology image are segmented into cellular compartments (e.g., epithelial and stromal compartments). Second, the heterogeneity in the different cellular compartments are examined based on a clustering algorithm. Tissue can then be characterized in terms of inertia (or other spatial measures or features), which can be used to recognize disease. In some instances, multidimensional inertia (i.e., inertia computed in different cellular compartments or clustered components) can be used as an indicator of disease and its outcome.
    Type: Grant
    Filed: October 1, 2021
    Date of Patent: July 1, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Rohit Bhargava, Shachi Mittal
  • Patent number: 12342775
    Abstract: A rice cultivar designated Taurus is disclosed herein. The present invention provides seeds, plants, and plant parts derived from rice cultivar Taurus. Further, it provides methods for producing a rice plant by crossing Taurus with itself or another rice variety. The invention also encompasses any rice seeds, plants, and plant parts produced by the methods disclosed herein, including those in which additional traits have been transferred into Taurus through the introduction of a transgene or by breeding Taurus with another rice cultivar.
    Type: Grant
    Filed: December 8, 2022
    Date of Patent: July 1, 2025
    Assignee: The Board of Trustees of the University of Arkansas
    Inventor: Xueyan Sha
  • Patent number: 12344666
    Abstract: Isolated polypeptides having enhanced affinity for a PDGF receptor and/or a VEGF receptor are provided. Compositions comprising the polypeptides and methods of use thereof are also provided.
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: July 1, 2025
    Assignees: Washington University, The Board of Trustees of the University of Illinois
    Inventors: Princess Imoukhuede, Erik Procko
  • Patent number: 12348281
    Abstract: A system for co-transmitting discrete power and data over a common high frequency channel includes a power transmitting node, a power receiving node, a data transmitting node, a data receiving node, a power transmitting switch, a power receiving switch, a data transmitting switch, a data receiving switch, a primary power switch, a secondary power switch, a common high frequency channel, a first control unit, and a second control unit. When the primary power switch, power transmitting switch, and power receiving switch are in an activated state, a power signal is transmitted over the common high frequency channel from the power transmitting node to the power receiving node. When the secondary power switch, data transmitting switch, and data receiving switch are in an activated state, a data signal is transmitted over the common high frequency channel from the data transmitting node to the data receiving node.
    Type: Grant
    Filed: February 7, 2022
    Date of Patent: July 1, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Sudip K. Mazumder, Ankit Gupta
  • Patent number: 12343136
    Abstract: The present disclosure provides methods and systems for improved rehabilitation of ankle motion by visually-driven priming of motor movement. The methods and systems include a sensor configured to measure ankle angle. The generated signal may be used to determine a maximal range of angles the user is capable of generating in order to calibrate the system. Subsequently, the signal from the sensor may be used to display the user location relative to an indication used to prime the motor movement. User performance may be tracked and performance-based awards given to increase rehabilitative outcome. The method and systems may encourage increased patient compliance by providing a comfortable, effective mode of ankle rehabilitation.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: July 1, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventor: Sangeetha Madhavan
  • Patent number: 12337347
    Abstract: A device includes a pair of substrate layer corresponding to a carrier substrate, an intermediary layer disposed on the pair of substrate layers, a cavity region disposed between the pair of substrate layers underneath the intermediary layer, a piezoelectric layer including a lithium-based film disposed on the intermediary layer, and a plurality of interdigital transducer electrodes disposed on the piezoelectric layer. The plurality of interdigital transducer electrodes includes an outer signal electrode, an inner signal electrode, an outer ground electrode and an inner ground electrode.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: June 24, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Songbin Gong, Ruochen Lu
  • Patent number: 12342449
    Abstract: An apparatus includes a printed circuit board (PCB), a power component disposed on the PCB, the power component to generate heat, and a multilayered coating disposed over the power component and at least a portion of the PCB to dissipate heat from the power component, the multilayered including: an electrical insulation layer comprising a non-polar compound and disposed on the power component and the at least a portion of the PCB; a chromium layer disposed on the electrical insulation layer; and a copper layer disposed on the chromium layer that is at least 10 microns (?m) thick, the copper layer conformally adhered to a top of the power component and to the PCB.
    Type: Grant
    Filed: September 27, 2022
    Date of Patent: June 24, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Tarek Gebrael, Arielle R. Gamboa, Jiaqi Li, Nenad Miljkovic, Shayan Aflatounian
  • Patent number: 12329794
    Abstract: A method for treating a subject with cancer by administering to the subject a therapeutically effective amount of a recombinant Herpes Simplex Virus-1 (HSV-1) that expresses only a C-terminal portion of ?134.5 protein (e.g., amino acid residues 147-263) with no wild-type or intact ?134.5 protein expression is provided. The recombinant HSV-1 of this invention instigates immune activation, selectively replicates in cancer cells, and resists clearance by interferon.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: June 17, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Bin He, Xing Liu
  • Publication number: 20250170529
    Abstract: Charged ultrafiltration membranes are synthesized by thermally initiated free-radical polymerization of sodium styrene sulfonate in the pores of an ultrafiltration pre-cursor membrane. The resulting grafted chains of the charged UF membrane provide significant negative charge to maintain nearly complete rejection of proteins at significantly higher flux.
    Type: Application
    Filed: July 6, 2023
    Publication date: May 29, 2025
    Applicants: fairlife, LLC, The Board of Trustees of The University of Alabama
    Inventors: Stephen Michael Christopher RITCHIE, Shakeel UR REHMAN, Robert Connor SCOTT
  • Patent number: RE50514
    Abstract: A method for treating a subject having a diseased or atrophic state of fibrotic tissue, kidney disease and associated nerve endings, or for promoting tissue regeneration in muscle tissue is accomplished through exposing the tissue with a laser light having a wavelength of about 400 nm to about 700 nm, or more preferably having a wavelength of about 405 nm, about 532 nm, about 635 nm, or a combination thereof. Subsequent to exposure, mesenchymal stem cells can be administered to the subject. After the administration of mesenchymal stem cells, the tissue is further exposed to laser light having a wavelength of about 400 nm to about 700 nm, or a laser light having a single wavelength of about 400 nm to about 700 nm. The mesenchymal cells can be interferon gamma activated.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: August 5, 2025
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Amelia Bartholomew, Megan O'Connor, Rachana Patil