Patents Assigned to The Board of Trustees of the University of Illionis
  • METHODS, COMPOSITIONS AND ARTICLES OF MANUFACTURE FOR CONTRIBUTING TO THE TREATMENT OF CANCERS
    Publication number: 20130102543
    Abstract: Methods, compositions and articles of manufacture for contributing to the treatment of cancers, including solid tumors, are disclosed. The methods, compositions and articles of manufacture can utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of a chemotherapeutic agent.
    Type: Application
    Filed: December 11, 2012
    Publication date: April 25, 2013
    Applicants: Spectrum Pharmaceuticals, Inc., The Board of Trustees of the University of Illionis
    Inventors: The Board of Trustees of the University of Illinois, Spectrum Pharmaceuticals, Inc.
  • Compounds and methods for treatment of cancer and modulation of programmed cell death for melanoma and other cancer cells
    Patent number: 7632972
    Abstract: Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. The generation of synthetic combinatorial libraries and the evaluation of library member compounds regarding induction of apoptosis selectively in cancer cells are disclosed. Compounds, methods of making the compounds, and therapeutic methods with application against breast cancer cells, melanoma cancer cells, colon cancer cells, and other cancer cells are described.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: December 15, 2009
    Assignee: The Board of Trustees of the University of Illionis
    Inventors: Paul J. Hergenrother, Vitaliy Nesterenko, Karson Putt, Brittany Joy Allen, Robin Shane Dothager, Benjamin James Leslie