Patents Assigned to The Board of Trustees Operating Michigan State University
  • Process for the preparation of 1,5-dideoxy-1,5-imino hexitols from oximes or imines
    Publication number: 20020052505
    Abstract: A process for the preparation of 1,5-dideoxy -1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.
    Type: Application
    Filed: October 4, 2001
    Publication date: May 2, 2002
    Applicant: Board of Trustees Operating Michigan State University
    Inventors: Rawle I. Hollingsworth, Gabriela Pistia-Brueggeman
  • Process for the preparation of hybrid mesoporous molecular sieve silicas from amine surfactants
    Publication number: 20020051745
    Abstract: Hybrid mesoporous molecular sieve silica compositions which have intergrown wormhole domains and lamellar or hexagonal domains and prepared from mixtures of water soluble silicate precursors and amine surfactant templates through a neutralization reaction are described. The silica compositions are stable above 600° C.
    Type: Application
    Filed: January 18, 2001
    Publication date: May 2, 2002
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Thomas J. Pinnavaia, Thomas R. Pauly, Seong-Su Kim
  • Process for the preparation of 1,5-dideoxy-1,5-imino hexitols from oximes or imines
    Publication number: 20020052506
    Abstract: A process for the preparation of 1,5-dideoxy -1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.
    Type: Application
    Filed: October 4, 2001
    Publication date: May 2, 2002
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Rawle I. Hollingsworth, Gabriela Pistia-Brueggeman
  • Apparatus and method for measuring infiltration flow rate
    Patent number: 6351989
    Abstract: An apparatus and method for measuring the infiltration flow rate into the passenger compartment of a moving motor vehicle includes a controlled source of a distinct, miscible gas such as carbon dioxide (CO2) a plurality of sensors disposed about the compartment to continuously monitor the concentration of such miscible gas over time and a multi-channel data storage device which discretely stores the concentration data from such plurality of sensors for later analysis and computation. The decay rate of the miscible gas concentration is a function of the infiltration/exfiltration rate.
    Type: Grant
    Filed: June 17, 1999
    Date of Patent: March 5, 2002
    Assignee: Michigan State University, Board of Trustees Operating Michigan State University
    Inventor: John F. Foss
  • Process and intermediate compounds for the preparation of pyrrolidines
    Publication number: 20020026072
    Abstract: Processes for the preparation of pyrrolidones (7 and 8) and pyrrolidines (9 and 10) from tri-O-acetyl-D-erythro-4-pentulosonic acid esters are described. The compounds are aza sugar analogs of D-ribofuranoside and are intermediates to drugs which regulate nucleoside and nucleic acid synthesis.
    Type: Application
    Filed: September 4, 2001
    Publication date: February 28, 2002
    Applicant: Board of Trustees operating Michigan State University
    Inventor: Rawle I. Hollingsworth
  • Process and intermediate compounds for the preparation of pyrrolidines
    Publication number: 20020026071
    Abstract: Processes for the preparation of pyrrolidones (7 and 8) and pyrrolidines (9 and 10) from tri-O-acetyl-D-erythro-4-pentulosonic acid esters are described. The compounds are aza sugar analogs of D-ribofuranoside and are intermediates to drugs which regulate nucleoside and nucleic acid synthesis.
    Type: Application
    Filed: September 4, 2001
    Publication date: February 28, 2002
    Applicant: Board of Trustees, operating Michigan State University
    Inventor: Rawle I. Hollingsworth
  • Process and intermediate compounds for the preparation of pyrrolidines
    Publication number: 20020026073
    Abstract: Processes for the preparation of pyrrolidones (7 and 8) and pyrrolidines (9 and 10) from tri-O-acetyl-D-erythro-4-pentulosonic acid esters are described. The compounds are aza sugar analogs of D-ribofuranoside and are intermediates to drugs which regulate nucleoside and nucleic acid synthesis.
    Type: Application
    Filed: September 4, 2001
    Publication date: February 28, 2002
    Applicant: Board of Trustees operating Michigan state University
    Inventor: Rawle I. Hollingsworth
  • Ultrastable porous aluminosilicate structures
    Publication number: 20020018747
    Abstract: Mesoporous hexagonal, cubic, lamellar, wormhole, or cellular foam aluminosilicates, gallosilicates and titanosilicates derived from protozeolitic seeds using an ionic structure directing agent are described. The silicon and aluminum, gallium or titanium centers in the structures are stable so that the framework of the structure does not collapse when heated in the presence of water or water vapor (steam). The steam stable compositions can be used as catalysts for hydrocarbon conversions, including the fluidized bed catalytic cracking and the hydrocracking of petroleum oils, and other reactions of organic compounds.
    Type: Application
    Filed: February 21, 2001
    Publication date: February 14, 2002
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Thomas J. Pinnavaia, Wenzhong Zhang, Yu Liu
  • Process and intermediate compounds for the preparation of pyrrolidines
    Publication number: 20020019561
    Abstract: Processes for the preparation of pyrrolidones (7 and 8) and pyrrolidines (9 and 10) from tri-O-acetyl-D-erythro-4-pentulosonic acid esters are described. The compounds are aza sugar analogs of D-ribofuranoside and are intermediates to drugs which regulate nucleoside and nucleic acid synthesis.
    Type: Application
    Filed: September 4, 2001
    Publication date: February 14, 2002
    Applicant: Board of Trustees operating Michigan State University
    Inventor: Rawle I. Hollingsworth
  • Process for the preparation of 1,5-dideoxy-1,5-imino hexitols from oximes or imines
    Publication number: 20020016447
    Abstract: A process for the preparation of 1,5-dideoxy-1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.
    Type: Application
    Filed: October 4, 2001
    Publication date: February 7, 2002
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Rawle I. Hollingsworth, Gabriela Pistia-Brueggeman
  • Process for the preparation of 1,5-dideoxy-1,5-imino hexitols from oximes or imines
    Publication number: 20020016448
    Abstract: A process for the preparation of 1,5-dideoxy -1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.
    Type: Application
    Filed: October 4, 2001
    Publication date: February 7, 2002
    Applicant: Board of Trustees Operating Michigan State University
    Inventors: Rawle I. Hollingsworth, Gabriela Pistia-Brueggeman
  • Compositions and methods for protecting cultivated plants from herbicidal injury
    Publication number: 20020010096
    Abstract: Compositions comprising a herbicide wherein it is desired that the compound not be retained by the plant foliage, and a repellant adjuvant, wherein the repellant modifies the surface properties of the composition so that retention of the composition on foliage of a cultivated plant is reduced are described. In particular, the herbicide composition comprises a repellant adjuvant that is an aqueous solution of an alkyltrialkoxysilane such as methyltrimethoxysilane and a water soluble silane coupling agent such as N-(2-aminoethyl)-3-aminopropyltrimethoxysilane or an aqueous solution of an organosiliconate such as sodium methyl siliconate. Methods are described for using these compositions to prevent weeds without injury to cultivated plants, which plants include crop plants, food plants, turfgrass, ornamental plants, and garden plants.
    Type: Application
    Filed: February 6, 2001
    Publication date: January 24, 2002
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Donald Penner, Christy L. Sprague, Richard F. Burow
  • Hybrid genes incorporating a DNA fragment containing at least one gene encoding an insecticidal protein and a gene encoding a glutamine synthase inhibitor, plasmids, transformed cyanobacteria expressing such proteins and method for use as biocontrol agent
    Patent number: 6335008
    Abstract: Cyanobacteria incorporating a gene from Bacillus sp. encoding for insecticidal proteins (endotoxins) is described. The endotoxins are particularly effective against Diptera (mosquito) larvae. Recombinant vectors for transforming DNA fragments of the endotoxin gene or genes into the Cyanobacterium are described. The Cyanobacteria are easily grown in ponds or the like where the mosquitos or other insects breed.
    Type: Grant
    Filed: February 18, 1992
    Date of Patent: January 1, 2002
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Mark Albert Vaeck, Wipa Chungjatupornchai, Lee McIntosh
  • Compositions for providing a chemical to a microorganism
    Patent number: 6331300
    Abstract: A method and composition for microbial remediation or other treatment of chemicals is described. The method particularly uses solidified oils or oils impregnated into inert particles or particles which release nutrient medium over time.
    Type: Grant
    Filed: October 22, 1998
    Date of Patent: December 18, 2001
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Michael J. Dybas, Craig S. Criddle, Michael E. Witt
  • Process for the preparation of 1,5-dideoxy-1,5-imino hexitols from oximes or imines
    Publication number: 20010049443
    Abstract: A process for the preparation of 1,5-dideoxy —1,5-imino hexitols of a hexose sugars from novel hydroxyl protected oxime intermediates. The process includes formation of a lactam which is reduced to the hexitol. The hexitols are useful as drugs.
    Type: Application
    Filed: March 28, 2001
    Publication date: December 6, 2001
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Rawle I. Hollingsworth, Gabriela Pistia-Brueggeman
  • Method and apparatus for growing cells using gas or liquid aphrons
    Patent number: 6326203
    Abstract: A method and bioreactor (10) apparatus is described for maintaining cells in a culture medium containing gas or liquid aphrons. A preferred microbubble generator (42, 42A) of a gas which is necessary for maintaining the cells to produce plant described chemicals is described. Bioparticles (11) containing magnetically susceptible particles are provided in a column (12) surrounded by solenoids (13, 14, 14A) which act to hold the bioparticles in position in the column. Preferably, one of the solenoids with a magnetically susceptible screen (24) acts as a valve to allow a portion of the bioparticles to be removed from the column.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: December 4, 2001
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Robert Mark Worden, Tyler T. Ames
  • Process for the preparation of polymers of dimeric cyclic esters
    Publication number: 20010044514
    Abstract: The present invention provides a process for the direct synthesis of high melting polymers made from dimeric cyclic esters. In particular, the present invention provides a process for synthesis of polylactic acid (PLA) from racemic materials such as racemic lactide and polymandelide from mandelide. The process further provides racemic metal organic ligand catalysts such as racemic salbinap that catalyzes the polymerization of racemic dimeric cyclic ester monomers to a polylactide stereocomplex. Polymandelide and mixed dimeric cyclic esters are also prepared in the presence of low amounts of water.
    Type: Application
    Filed: December 13, 2000
    Publication date: November 22, 2001
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Gregory L. Baker, Milton R. Smith
  • Conductive isostructural compounds
    Patent number: 6312617
    Abstract: A family of isostructural compounds have been prepared having the general formula AnPbmBinQ2n+m. These compounds possess a NaCl lattice type structure as well as low thermal conductivity and controlled electrical conductivity. Furthermore, the electrical properties can be controlled by varying the values for n and m. These isostructural compounds can be used for semiconductor applications such as detectors, lasers and photovoltaic cells. These compounds also have enhanced thermoelectric properties making them excellent semiconductor materials for fabrication of thermoelectric devices.
    Type: Grant
    Filed: October 11, 1999
    Date of Patent: November 6, 2001
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Mercouri G. Kanatzidis, Duck Young Chung, Stephane DeNardi, Sandrine Sportouch
  • Dexterous articulated linkage for surgical applications
    Patent number: 6309403
    Abstract: A surgical instrument includes an actuator, a tool, and a positioning apparatus. The positioning apparatus includes a gear link structure operably coupling the tool to the actuator for moving the tool in a first direction defining a first degree of freedom and in a second direction defining a second degree of freedom.
    Type: Grant
    Filed: May 27, 1999
    Date of Patent: October 30, 2001
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Mark A. Minor, Ranjan Mukherjee
  • Method and system for creating designs using internet-based agents
    Patent number: 6295535
    Abstract: An apparatus and method are provided for collaboratively generating characteristic data regarding at least one characteristic of a component. A querying ontological data structure is provided for structuring characteristic data transmitted across the network. A querying communicator which is connected to the network generates and structures based upon the querying ontological structure a first query which regards a first characteristic of the component and wherein the first query is to be sent across the network. The first component characteristic communicator which is connected to the network receives via the network the generated first query from the querying communicator. A first component characteristic determinator which is connected to the first characteristic communicator determines first characteristic data regarding the first characteristic of the component based upon the first query.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: September 25, 2001
    Assignee: Board of Trustees Operating Michigan State University
    Inventors: Clark J. Radcliffe, Jon H. Sticklen