Patents Assigned to THE BOARD OF TRUSTEES OPERATING
  • Publication number: 20070128613
    Abstract: The present invention relates to molecular diagnostics. In particular, the present invention relates to PCR based diagnostics for the typing of Group B streptococci.
    Type: Application
    Filed: December 6, 2005
    Publication date: June 7, 2007
    Applicant: The Board of Trustees Operating Michigan State University
    Inventors: Dele Davies, David Lacher, Thomas Whittam, Shannon Manning
  • Patent number: 7226764
    Abstract: The present invention is directed to compositions and methods related to the synthesis and modification of uridine-5?-diphospho-sulfoquinovose (UDP-SQ). In particular, the methods of the present invention comprise the utilization of recombinant enzymes from Arabidopsis thaliana, UDP-glucose, and a sulfur donor to synthesize UDP-SQ, and the subsequent modification of UDP-SQ to form compounds including, but not limited to, 6-sulfo-?-D-quinovosyl diaclyglycerol (SQDG) and alkyl sulfoquinovoside. The compositions and methods of the invention provide a more simple, rapid means of synthesizing UDP-SQ, and the subsequent modification of UDP-SQ to compounds including, but not limited to, SQDG.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: June 5, 2007
    Assignee: The Board of Trustees Operating Michigan State University
    Inventors: Christoph Benning, Sherrie Lea Sanda, Bin Yu
  • Publication number: 20070107764
    Abstract: A thermoelectric material of the general formula Ag1-XMmM?Q2+m, wherein M is selected from the group consisting of Pb, Sn, Ca, Sr, Ba, divalent transition metals, and combinations thereof; M? is selected from the group consisting of Bi, Sb, and combinations thereof; Q is selected from the group consisting of Se, Te, S, and combinations thereof; 8?m?24; and 0.01?x ?0.7. In embodiments of the invention, the compositions exhibit n-type semiconductor properties. In preferred embodiments, x is from 0.1 to 0.3, and m is from 10 to 18. The compositions may be synthesized by adding stoichiometric amounts of starting materials comprising Ag, M, M?, and Q to a reaction vessel, heating the starting materials to a temperature and for a period of time sufficient to melt the materials, and cooling the reaction product at a controlled rate of cooling.
    Type: Application
    Filed: August 25, 2004
    Publication date: May 17, 2007
    Applicant: BOARD OF TRUSTEES OPERATING
    Inventors: Mercouri Kanatzidis, Kuei-Fang Hsu
  • Publication number: 20070092532
    Abstract: Vaccine compositions for preventing the onset or induction of arthritis in a subject susceptible to developing arthritis, comprising an arthritic protective peptide comprising the amino acid sequence of SEQ ID NO: 1. In various embodiments, the anti-arthritic peptide is admixed with an adjuvant in a pharmaceutically acceptable carrier. Methods include preventing arthritis in a human or other mammal subject comprising administering the arthritic protective peptide to the subject.
    Type: Application
    Filed: October 25, 2006
    Publication date: April 26, 2007
    Applicant: Board of Trustees Operating Michigan State University
    Inventor: Robert Root-Bernstein
  • Publication number: 20070087424
    Abstract: Novel enzymes and novel enzymatic pathways for the pyruvate-based synthesis of shikimate or at least one intermediate thereto or derivative thereof, nucleic acids encoding the enzymes, cells transformed therewith, and kits containing said enzymes, cells, or nucleic acid. A KDPGal aldolase is used to perform condensation of pyruvate with D-erythrose 4-phosphate to form 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP); a 3-dehydroquinate synthase is used to convert the DAHP to 3-dehydroquinate (DHQ); DHQ dehydratase can then convert DHQ to the key shikimate intermediate, 3-dehydroshikimate.
    Type: Application
    Filed: September 24, 2004
    Publication date: April 19, 2007
    Applicant: BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERS
    Inventor: John Frost
  • Patent number: 7181811
    Abstract: This application relates to a micro-fastening system and, more particularly, to a mechanical micro-fastening system employing a plurality of mating nanoscale fastening elements (16, 18) and a method of manufacturing a micro-fastening system. The mating nanoscale fastening elements (16, 18) are formed by functionalizing nanotubes having an ordered array of hexagons with pentagons and heptagons at particular heterojunctions.
    Type: Grant
    Filed: February 11, 1999
    Date of Patent: February 27, 2007
    Assignee: Board of Trustees operating Michigan State University
    Inventors: David Tomanek, Richard Enbody, Young-Kyun Kwon
  • Publication number: 20070037258
    Abstract: The present invention relates to methods and compositions for enhancing protein folding. In particular, the present invention relates to methods for directing recombinantly expressed proteins to protein folding chaperones.
    Type: Application
    Filed: August 9, 2005
    Publication date: February 15, 2007
    Applicant: The Board of Trustees Operating Michigan State University
    Inventor: Larry Snyder
  • Publication number: 20070034818
    Abstract: A method for producing a plurality of thin film actuators is disclosed. The method includes depositing a film of a shape memory alloy material onto a polyimide film to form a shape memory alloy construction. The shape memory alloy construction is strained from 2 to 8%. Post processing is conducted on the shape memory alloy construction after the step of imparting a 2 to 8% strain. This post processing can be the deposition of additional layers of the slicing of the actuators. Various shape memory metal actuators are disclosed.
    Type: Application
    Filed: April 15, 2004
    Publication date: February 15, 2007
    Applicant: BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY
    Inventor: David Grummon
  • Patent number: 7154022
    Abstract: The present invention relates to divinyl ether synthase genes, proteins, and methods of their use. The present invention encompasses both native and recombinant wild-type forms of the synthase, as well as mutants and variant forms, some of which possess altered characteristics relative to the wild-type synthase. The present invention also relates to methods of using divinyl ether synthase genes and proteins, including in their expression in transgenic organisms and in the production of divinyl ether fatty acids, and to methods of suing divinyl ether fatty acids, including in the protection of plants from pathogens.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: December 26, 2006
    Assignee: Board of Trustees Operating Michigan State University
    Inventors: Gregg A. Howe, Aya Itoh
  • Publication number: 20060277627
    Abstract: The present invention relates to compositions and methods for providing aphid resistance in plants. More particularly, the invention relates to compositions and methods for using aphid resistant germplasm for breeding soybean aphid resistant soybean plants, including but not limited to cultivars, varieties, lines and methods of breeding the same for commercial use, the breeding methods further involving identifying and using genetic markers for aphid resistant traits.
    Type: Application
    Filed: May 18, 2006
    Publication date: December 7, 2006
    Applicant: The Board of Trustees Operating Michigan State University
    Inventors: Dechun Wang, Clarice Mensah, Christina DiFonzo
  • Patent number: 7134349
    Abstract: An improved microforce sensing system is provided. The microforce sensing system includes: a force sensor configured to detect a contact force exerted on a contact tip of the cantilever and operable to generate a signal indicative of the contact force, where the cantilever is constructed from a polyvinylidene fluoride material in the form of a substantially rectangular plate or other suitable shapes; and a processing circuit adapted to receive the signal from the force sensor and operable to determine the contact force exerted on the tip by integrating the signal from the force sensor.
    Type: Grant
    Filed: July 7, 2004
    Date of Patent: November 14, 2006
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Ning Xi, Yantao Shen, Fathi Salem
  • Patent number: 7132165
    Abstract: Novel lamellar mesoporous silica compositions which can contain functional inorganic elements and organic functional groups as part of the lamellar silica framework structure are described. The compositions are prepared using gemini amine surfactants as templates or structure directing agents. The compositions have novel high temperature and hydrothermal stability and unique fundamental particle structures.
    Type: Grant
    Filed: October 17, 2002
    Date of Patent: November 7, 2006
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Thomas J. Pinnavaia, Seong-Su Kim, Wenzhong Zhang
  • Patent number: 7122367
    Abstract: The present invention relates to diacylglycerol acyltransferase genes and proteins, and methods of their use. In particular, the invention describes genes and proteins that exhibit both long-chain acyltransferase and acetyltransferase activity. The present invention encompasses both native and recombinant wild-type forms of the transferase, as well as mutants and variant forms, some of which possess altered characteristics relative to the wild-type transferase. The present invention also relates to methods of using diacylglycerol acyltransferase genes and proteins, including in their expression in transgenic organisms and in the production of acetyl-glycerides in plant oils, and in particular seed oils.
    Type: Grant
    Filed: June 2, 2004
    Date of Patent: October 17, 2006
    Assignee: Board of Trustees Operating Michigan State University
    Inventors: Anne Milcamps, David A. Pan, Michael R. Pollard
  • Patent number: 7111783
    Abstract: An automated dimensional inspection system is provided that modifies sensor planning based on real-time measurement feedback. The dimensional inspection system includes a sensor planner, an error map generator, and a sensor affixed to a movable member. The sensor planner is adapted to receive three dimensional design data for a workpiece to be measured and generate path data in part based on the dimensional design data for the workpiece, where the path data is indicative of a path for moving the sensor in relation to the surface of the workpiece. The error map generator is adapted to receive the dimensional design data and the three dimensional measurement data for the workpiece, and determine error data between the measurement data and the dimensional design data. Based on the error data, the sensor planner is able to further modify the path data for the sensor to increase the measurement accuracy.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: September 26, 2006
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Ning Xi, Chen Heping, Quan Shi
  • Patent number: 7105811
    Abstract: A control system and apparatus for use with laser ionization is provided. In another aspect of the present invention, the apparatus includes a laser, pulse shaper, detection device and control system. A further aspect of the present invention employs a femtosecond laser and a mass spectrometer. In yet other aspects of the present invention, the control system and apparatus are used in MALDI, chemical bond cleaving, protein sequencing, photodynamic therapy, optical coherence tomography and optical communications processes.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: September 12, 2006
    Assignee: Board of Trustees operating Michigian State Univesity
    Inventors: Marcos Dantus, Vadim V. Lozovoy
  • Publication number: 20060199970
    Abstract: A process for the preparation of a fuel oil (diesel fuel or heating oil) composition which is a mixture of an alkanol tranesterified fatty acid ester triglyceride and an acetal of glycerol is described. The process preferably provides a prestep of the formation of at least some of the alkanol transesterified triglyceride containing the glycerol for use in the formation of the acetal of glycerol. The composition can also be formed from a reaction of 1,1- dimethoxy- or 1,1-diethoxyethane and glycerol to form the acetal in the alkanol transesterified triglyceride.
    Type: Application
    Filed: February 28, 2006
    Publication date: September 7, 2006
    Applicant: Michigan State University, Board of Trustees operating
    Inventors: Dennis Miller, Lars Peereboom, Aspi Kolah, Navinchandra Asthana, Carl Lira
  • Patent number: 7091369
    Abstract: The present invention relates to fatty acids. In particular, the present invention provides polyconjugated fatty acids, and methods of their synthesis and their use.
    Type: Grant
    Filed: April 7, 2004
    Date of Patent: August 15, 2006
    Assignee: Board of Trustees Operating Michigan State University
    Inventors: William Smith, Dmitry V. Kuklev
  • Patent number: 7081565
    Abstract: The present invention relates to novel seed specific promoter regions. The present invention further provide methods of producing proteins and other products of interest and methods of controlling expression of nucleic acid sequences of interest using the seed specific promoter regions. The present invention also provides methods of identifying and isolating novel seed specific promoters.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: July 25, 2006
    Assignee: Board of Trustees Operating Michigan State University
    Inventors: John B. Ohlrogge, Christoph Benning, Hongbo Gao, Thomas Arno Alfred Girke, Joseph A. White
  • Publication number: 20060148966
    Abstract: Graphite nanoplatelets of expanded graphite and composites and products produced therefrom are described. The preferred method of expanding the graphite is by microwaves or other radiofrequency wave treatment of intercalated graphite. The expanded graphite is preferably then crushed to nanometer (substantially all 200 microns or less). The expanded graphite is used in polymer composites. The expanded graphite is particularly useful for batteries, anodes and fuel cells.
    Type: Application
    Filed: February 27, 2006
    Publication date: July 6, 2006
    Applicant: Board of Trustees operating Michigan State University
    Inventors: Lawrence Drzal, Hiroyuki Fukushima
  • Patent number: RE39640
    Abstract: A family of isostructural compounds have been prepared having the general formula AnPbmBinO2n+m. These compounds possess a NaCl lattice type structure as well as low thermal conductivity and controlled electrical conductivity. Furthermore, the electrical properties can be controlled by varying the values for n and m. These isostructural compounds can be used for semiconductor applications such as detectors, lasers and photovoltaic cells. These compounds also have enhanced thermoelectric properties making them excellent semiconductor materials for fabrication of thermoelectric devices.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: May 22, 2007
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Mercouri G. Kanatzidis, Duck-Young Chung, Stephane DeNardi, Sandrine Sportouch