Patents Assigned to THE BOARD OF TRUSTEES OPERATING
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Publication number: 20070128613Abstract: The present invention relates to molecular diagnostics. In particular, the present invention relates to PCR based diagnostics for the typing of Group B streptococci.Type: ApplicationFiled: December 6, 2005Publication date: June 7, 2007Applicant: The Board of Trustees Operating Michigan State UniversityInventors: Dele Davies, David Lacher, Thomas Whittam, Shannon Manning
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Patent number: 7226764Abstract: The present invention is directed to compositions and methods related to the synthesis and modification of uridine-5?-diphospho-sulfoquinovose (UDP-SQ). In particular, the methods of the present invention comprise the utilization of recombinant enzymes from Arabidopsis thaliana, UDP-glucose, and a sulfur donor to synthesize UDP-SQ, and the subsequent modification of UDP-SQ to form compounds including, but not limited to, 6-sulfo-?-D-quinovosyl diaclyglycerol (SQDG) and alkyl sulfoquinovoside. The compositions and methods of the invention provide a more simple, rapid means of synthesizing UDP-SQ, and the subsequent modification of UDP-SQ to compounds including, but not limited to, SQDG.Type: GrantFiled: November 8, 2000Date of Patent: June 5, 2007Assignee: The Board of Trustees Operating Michigan State UniversityInventors: Christoph Benning, Sherrie Lea Sanda, Bin Yu
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Publication number: 20070107764Abstract: A thermoelectric material of the general formula Ag1-XMmM?Q2+m, wherein M is selected from the group consisting of Pb, Sn, Ca, Sr, Ba, divalent transition metals, and combinations thereof; M? is selected from the group consisting of Bi, Sb, and combinations thereof; Q is selected from the group consisting of Se, Te, S, and combinations thereof; 8?m?24; and 0.01?x ?0.7. In embodiments of the invention, the compositions exhibit n-type semiconductor properties. In preferred embodiments, x is from 0.1 to 0.3, and m is from 10 to 18. The compositions may be synthesized by adding stoichiometric amounts of starting materials comprising Ag, M, M?, and Q to a reaction vessel, heating the starting materials to a temperature and for a period of time sufficient to melt the materials, and cooling the reaction product at a controlled rate of cooling.Type: ApplicationFiled: August 25, 2004Publication date: May 17, 2007Applicant: BOARD OF TRUSTEES OPERATINGInventors: Mercouri Kanatzidis, Kuei-Fang Hsu
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Publication number: 20070092532Abstract: Vaccine compositions for preventing the onset or induction of arthritis in a subject susceptible to developing arthritis, comprising an arthritic protective peptide comprising the amino acid sequence of SEQ ID NO: 1. In various embodiments, the anti-arthritic peptide is admixed with an adjuvant in a pharmaceutically acceptable carrier. Methods include preventing arthritis in a human or other mammal subject comprising administering the arthritic protective peptide to the subject.Type: ApplicationFiled: October 25, 2006Publication date: April 26, 2007Applicant: Board of Trustees Operating Michigan State UniversityInventor: Robert Root-Bernstein
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Publication number: 20070087424Abstract: Novel enzymes and novel enzymatic pathways for the pyruvate-based synthesis of shikimate or at least one intermediate thereto or derivative thereof, nucleic acids encoding the enzymes, cells transformed therewith, and kits containing said enzymes, cells, or nucleic acid. A KDPGal aldolase is used to perform condensation of pyruvate with D-erythrose 4-phosphate to form 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP); a 3-dehydroquinate synthase is used to convert the DAHP to 3-dehydroquinate (DHQ); DHQ dehydratase can then convert DHQ to the key shikimate intermediate, 3-dehydroshikimate.Type: ApplicationFiled: September 24, 2004Publication date: April 19, 2007Applicant: BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSInventor: John Frost
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Patent number: 7181811Abstract: This application relates to a micro-fastening system and, more particularly, to a mechanical micro-fastening system employing a plurality of mating nanoscale fastening elements (16, 18) and a method of manufacturing a micro-fastening system. The mating nanoscale fastening elements (16, 18) are formed by functionalizing nanotubes having an ordered array of hexagons with pentagons and heptagons at particular heterojunctions.Type: GrantFiled: February 11, 1999Date of Patent: February 27, 2007Assignee: Board of Trustees operating Michigan State UniversityInventors: David Tomanek, Richard Enbody, Young-Kyun Kwon
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Publication number: 20070037258Abstract: The present invention relates to methods and compositions for enhancing protein folding. In particular, the present invention relates to methods for directing recombinantly expressed proteins to protein folding chaperones.Type: ApplicationFiled: August 9, 2005Publication date: February 15, 2007Applicant: The Board of Trustees Operating Michigan State UniversityInventor: Larry Snyder
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Publication number: 20070034818Abstract: A method for producing a plurality of thin film actuators is disclosed. The method includes depositing a film of a shape memory alloy material onto a polyimide film to form a shape memory alloy construction. The shape memory alloy construction is strained from 2 to 8%. Post processing is conducted on the shape memory alloy construction after the step of imparting a 2 to 8% strain. This post processing can be the deposition of additional layers of the slicing of the actuators. Various shape memory metal actuators are disclosed.Type: ApplicationFiled: April 15, 2004Publication date: February 15, 2007Applicant: BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITYInventor: David Grummon
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Patent number: 7154022Abstract: The present invention relates to divinyl ether synthase genes, proteins, and methods of their use. The present invention encompasses both native and recombinant wild-type forms of the synthase, as well as mutants and variant forms, some of which possess altered characteristics relative to the wild-type synthase. The present invention also relates to methods of using divinyl ether synthase genes and proteins, including in their expression in transgenic organisms and in the production of divinyl ether fatty acids, and to methods of suing divinyl ether fatty acids, including in the protection of plants from pathogens.Type: GrantFiled: October 5, 2001Date of Patent: December 26, 2006Assignee: Board of Trustees Operating Michigan State UniversityInventors: Gregg A. Howe, Aya Itoh
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Publication number: 20060277627Abstract: The present invention relates to compositions and methods for providing aphid resistance in plants. More particularly, the invention relates to compositions and methods for using aphid resistant germplasm for breeding soybean aphid resistant soybean plants, including but not limited to cultivars, varieties, lines and methods of breeding the same for commercial use, the breeding methods further involving identifying and using genetic markers for aphid resistant traits.Type: ApplicationFiled: May 18, 2006Publication date: December 7, 2006Applicant: The Board of Trustees Operating Michigan State UniversityInventors: Dechun Wang, Clarice Mensah, Christina DiFonzo
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Patent number: 7134349Abstract: An improved microforce sensing system is provided. The microforce sensing system includes: a force sensor configured to detect a contact force exerted on a contact tip of the cantilever and operable to generate a signal indicative of the contact force, where the cantilever is constructed from a polyvinylidene fluoride material in the form of a substantially rectangular plate or other suitable shapes; and a processing circuit adapted to receive the signal from the force sensor and operable to determine the contact force exerted on the tip by integrating the signal from the force sensor.Type: GrantFiled: July 7, 2004Date of Patent: November 14, 2006Assignee: Board of Trustees operating Michigan State UniversityInventors: Ning Xi, Yantao Shen, Fathi Salem
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Patent number: 7132165Abstract: Novel lamellar mesoporous silica compositions which can contain functional inorganic elements and organic functional groups as part of the lamellar silica framework structure are described. The compositions are prepared using gemini amine surfactants as templates or structure directing agents. The compositions have novel high temperature and hydrothermal stability and unique fundamental particle structures.Type: GrantFiled: October 17, 2002Date of Patent: November 7, 2006Assignee: Board of Trustees operating Michigan State UniversityInventors: Thomas J. Pinnavaia, Seong-Su Kim, Wenzhong Zhang
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Patent number: 7122367Abstract: The present invention relates to diacylglycerol acyltransferase genes and proteins, and methods of their use. In particular, the invention describes genes and proteins that exhibit both long-chain acyltransferase and acetyltransferase activity. The present invention encompasses both native and recombinant wild-type forms of the transferase, as well as mutants and variant forms, some of which possess altered characteristics relative to the wild-type transferase. The present invention also relates to methods of using diacylglycerol acyltransferase genes and proteins, including in their expression in transgenic organisms and in the production of acetyl-glycerides in plant oils, and in particular seed oils.Type: GrantFiled: June 2, 2004Date of Patent: October 17, 2006Assignee: Board of Trustees Operating Michigan State UniversityInventors: Anne Milcamps, David A. Pan, Michael R. Pollard
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Patent number: 7111783Abstract: An automated dimensional inspection system is provided that modifies sensor planning based on real-time measurement feedback. The dimensional inspection system includes a sensor planner, an error map generator, and a sensor affixed to a movable member. The sensor planner is adapted to receive three dimensional design data for a workpiece to be measured and generate path data in part based on the dimensional design data for the workpiece, where the path data is indicative of a path for moving the sensor in relation to the surface of the workpiece. The error map generator is adapted to receive the dimensional design data and the three dimensional measurement data for the workpiece, and determine error data between the measurement data and the dimensional design data. Based on the error data, the sensor planner is able to further modify the path data for the sensor to increase the measurement accuracy.Type: GrantFiled: June 25, 2004Date of Patent: September 26, 2006Assignee: Board of Trustees operating Michigan State UniversityInventors: Ning Xi, Chen Heping, Quan Shi
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Patent number: 7105811Abstract: A control system and apparatus for use with laser ionization is provided. In another aspect of the present invention, the apparatus includes a laser, pulse shaper, detection device and control system. A further aspect of the present invention employs a femtosecond laser and a mass spectrometer. In yet other aspects of the present invention, the control system and apparatus are used in MALDI, chemical bond cleaving, protein sequencing, photodynamic therapy, optical coherence tomography and optical communications processes.Type: GrantFiled: July 28, 2003Date of Patent: September 12, 2006Assignee: Board of Trustees operating Michigian State UnivesityInventors: Marcos Dantus, Vadim V. Lozovoy
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Publication number: 20060199970Abstract: A process for the preparation of a fuel oil (diesel fuel or heating oil) composition which is a mixture of an alkanol tranesterified fatty acid ester triglyceride and an acetal of glycerol is described. The process preferably provides a prestep of the formation of at least some of the alkanol transesterified triglyceride containing the glycerol for use in the formation of the acetal of glycerol. The composition can also be formed from a reaction of 1,1- dimethoxy- or 1,1-diethoxyethane and glycerol to form the acetal in the alkanol transesterified triglyceride.Type: ApplicationFiled: February 28, 2006Publication date: September 7, 2006Applicant: Michigan State University, Board of Trustees operatingInventors: Dennis Miller, Lars Peereboom, Aspi Kolah, Navinchandra Asthana, Carl Lira
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Patent number: 7091369Abstract: The present invention relates to fatty acids. In particular, the present invention provides polyconjugated fatty acids, and methods of their synthesis and their use.Type: GrantFiled: April 7, 2004Date of Patent: August 15, 2006Assignee: Board of Trustees Operating Michigan State UniversityInventors: William Smith, Dmitry V. Kuklev
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Patent number: 7081565Abstract: The present invention relates to novel seed specific promoter regions. The present invention further provide methods of producing proteins and other products of interest and methods of controlling expression of nucleic acid sequences of interest using the seed specific promoter regions. The present invention also provides methods of identifying and isolating novel seed specific promoters.Type: GrantFiled: November 30, 2001Date of Patent: July 25, 2006Assignee: Board of Trustees Operating Michigan State UniversityInventors: John B. Ohlrogge, Christoph Benning, Hongbo Gao, Thomas Arno Alfred Girke, Joseph A. White
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Publication number: 20060148966Abstract: Graphite nanoplatelets of expanded graphite and composites and products produced therefrom are described. The preferred method of expanding the graphite is by microwaves or other radiofrequency wave treatment of intercalated graphite. The expanded graphite is preferably then crushed to nanometer (substantially all 200 microns or less). The expanded graphite is used in polymer composites. The expanded graphite is particularly useful for batteries, anodes and fuel cells.Type: ApplicationFiled: February 27, 2006Publication date: July 6, 2006Applicant: Board of Trustees operating Michigan State UniversityInventors: Lawrence Drzal, Hiroyuki Fukushima
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Patent number: RE39640Abstract: A family of isostructural compounds have been prepared having the general formula AnPbmBinO2n+m. These compounds possess a NaCl lattice type structure as well as low thermal conductivity and controlled electrical conductivity. Furthermore, the electrical properties can be controlled by varying the values for n and m. These isostructural compounds can be used for semiconductor applications such as detectors, lasers and photovoltaic cells. These compounds also have enhanced thermoelectric properties making them excellent semiconductor materials for fabrication of thermoelectric devices.Type: GrantFiled: November 6, 2003Date of Patent: May 22, 2007Assignee: Board of Trustees operating Michigan State UniversityInventors: Mercouri G. Kanatzidis, Duck-Young Chung, Stephane DeNardi, Sandrine Sportouch