Patents Assigned to The Boots Co. PLC
  • Chemical process
    Patent number: 5079264
    Abstract: A process to prepare compounds of formula I ##STR1## in which n=0, 1 or 2 comprising the cyclization of compounds of formula II ##STR2## in which n=0, 1 or 2. The cyclization may be effected in the presence of an organic or inorganic base or thermally at a temperature in the range 40.degree.-160.degree. C.Compounds of formula II and certain analogues thereof are disclosed as cardiovascular agents.
    Type: Grant
    Filed: March 1, 1991
    Date of Patent: January 7, 1992
    Assignee: The Boots Co. PLC
    Inventors: Lachlan MaClean, David L. Roberts, Kenneth Barron, Kenneth J. Nichol, Albert E. Harrison
  • Use of N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine
    Patent number: 4939175
    Abstract: Use of N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine or a pharmacologically acceptable acid addition salt thereof for manufacture of a cerebral function improver for the treatment of cerebral function disorders, which is useful as an improver for cerebral function disorders such as amnestic syndrome, senile dementia and Parkinson's disease, since it can intensively activate the central nervous system, especially dopamine neuron, and also increase the spontaneous movement in human or animal.
    Type: Grant
    Filed: March 29, 1989
    Date of Patent: July 3, 1990
    Assignee: The Boots Co. PLC
    Inventors: Kiyoharu Ukai, Chiharu Masuda, Satoko Kubo, Teruo Mukai, Terutake Nakagawa