Patents Assigned to THE BRIGHAM AND WOMEN'S HOSPITAT . INC
  • Methods for determining response to a hypomethylating agent
    Patent number: 11015223
    Abstract: Disclosed are methods for predicting a response of a subject with myelodysplastic syndrome to treatment with a hypomethylating agent, for example using a sample obtained from the subject. The methods can be used to select a subject for treatment with a hypomethylating agent, and/or measure a subject's response to therapy and/or disease progression/regression. The methods include detecting, in a nucleic acid sample obtained from a subject, one or more mutations of any one or more genes selected from Table 3a.
    Type: Grant
    Filed: May 12, 2014
    Date of Patent: May 25, 2021
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, DANA-FARBER CANCER INSTITUTE, INC., THE BRIGHAM AND WOMEN'S HOSPITAT . INC
    Inventors: Rafael Bejar, Benjamin Ebert, Donna Neuberg, Kristen Stevenson