Patents Assigned to THE BROAD INSTITUE, INC.
  • Propeptide-luciferase fusion proteins and methods of use thereof
    Patent number: 10370697
    Abstract: The present invention provides nucleic acid constructs that encode fusion peptides comprising a bioluminescent protein and a precursor of a secreted peptide or protein expressed at the cell surface and high throughput screening assays using same.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: August 6, 2019
    Assignees: THE BROAD INSTITUE, INC., THE GENERAL HOSPITAL CORPORATION, INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
    Inventors: Sean Burns, David Altshuler, Amedeo Vetere