Abstract: A visible light-curable chitosan derivative, a hydrogel thereof, and a preparation method therefor are disclosed. The visible light-curable glycol chitosan derivative is curable by light in the visible light range and has a wound healing activity. A hydrogel obtained by cross-linkage of the visible light-curable glycol chitosan derivative using visible light has a wound healing effect per se, and further, a hydrogel obtained by cross-linkage in a combination of one or more growth factors has an excellent wound healing effect. In addition, a glycol chitosan hydrogel that can prevent the denaturation of contained drugs and growth factors due to the cross-linkage by visible light and is optimized for application to a wet dressing dosage form can be prepared.
Type:
Grant
Filed:
June 29, 2020
Date of Patent:
November 17, 2020
Assignee:
THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMY COOPERATION
Inventors:
Dae Hyeok Yang, Heung-Jae Chun, Dong In Seo
Abstract: A visible light-curable chitosan derivative, a hydrogel thereof, and a preparation method therefor are disclosed. The visible light-curable glycol chitosan derivative is curable by light in the visible light range and has a wound healing activity. A hydrogel obtained by cross-linkage of the visible light-curable glycol chitosan derivative using visible light has a wound healing effect per se, and further, a hydrogel obtained by cross-linkage in a combination of one or more growth factors has an excellent wound healing effect. In addition, a glycol chitosan hydrogel that can prevent the denaturation of contained drugs and growth factors due to the cross-linkage by visible light and is optimized for application to a wet dressing dosage form can be prepared.
Type:
Application
Filed:
June 29, 2020
Publication date:
October 15, 2020
Applicant:
THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMY COOPERATION
Inventors:
Dae Hyeok YANG, Heung-Jae Chun, Dong In Seo
Abstract: The present invention relates to a visible light-curable chitosan derivative, a hydrogel, and a preparation method therefor and, more specifically, to a visible light-curable glycol chitosan derivative which is cured by light in the visible light range and has wound healing ability, a hydrogel, and a preparation method therefor. A hydrogel obtained by cross-linkage of the visible light-curable glycol chitosan derivative according to the present invention using visible light has a wound healing effect per se, and further, a hydrogel obtained by cross-linkage in a combination of one or more growth factors has an excellent wound healing effect. In addition, a glycol chitosan hydrogel that can prevent the denaturation of contained drugs and growth factors due to the cross-linkage by visible light and is optimized for application to a wet dressing dosage form can be prepared.
Type:
Application
Filed:
June 19, 2017
Publication date:
July 4, 2019
Applicant:
THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMY COOPERATION
Inventors:
Dae Hyeok YANG, Heung-Jae CHUN, Dong In SEO