Abstract: Provided are a method, apparatus and system for prediction of a neonatal brain development prognosis. The computing device includes a memory; and at least one processor performing communication with the memory, wherein the processor is configured to extract cerebral blood flow (CBF) and brain tissue relaxation times T1 and T2 from the input magnetic resonance imaging (MRI) of a subject newborn; generate brain neurodevelopment prediction data of the subject newborn using a pregenerated brain neurodevelopment prediction model; and control the output of the generated brain neurodevelopment prediction data of the subject newborn.

Abstract: The present invention relates to a system and method for monitoring the safety of users in a shaded area, wherein location information about an RFID post installed in a shaded area is identified by means of an RFID tag, so that the location of a work group working in the shaded area can be transmitted to a control server in real time, and the control server compares the location of the work group with operation information about trains, thereby determining whether the work group is in danger or not, makes notification the same, so that the safety of the work group can be secured.

Abstract: A stent device including a stent coated with a photosensitizer, the stent including a pair of electrodes; and a circuit fixed to the stent, the circuit including a light emitting diode, a power receiving means for wirelessly receiving power from the outside, and converting the power to electric power; a second communicating means for receiving a control command from the outside; and a second control means for applying, based on the control command, the electric power to the electrodes causing an electric current to flow through the stent between the electrodes, the flow causing heating of the stent, and for controlling a temperature of the stent to provide hyperthermia therapy to a tumor, the second control means further for applying, based on the control command, the electric power to the light emitting diode to emit a predetermined wavelength of light to the photosensitizer to provide photodynamic therapy to the tumor.

Abstract: The present invention relates to an artificial bladder system having a double space divided by a partition wall and a wireless, non-powered urine fullness sensor using an RFID technology, which provides an artificial bladder system comprising: an outer wall that forms the outer shape of the artificial bladder, is inserted into the body, and has an inner space; a partition wall, wherein both ends are fixed to the inside of the outer wall, the inner space of the outer wall is divided into a double space of a urine reservoir and a working fluid space, and it is deformable according to amounts of the urine and the working fluid; and a urine fullness sensor installed in the working fluid space and sensing a urine fullness degree based on the deformation of the partition wall.

Abstract: The present invention relates to an exosome for stimulating T cells and the pharmaceutical use thereof. Immune exosomes secreted from artificial antigen-presenting cells which express HLA, CD32, and co-stimulatory molecules CD32, CD80, CD83, and 4-1BBL are used to stimulate naive CD8+ T cells whereby preventive and therapeutic effects on tumors, pathogen infections, or autoimmune diseases can be provided.

Abstract: Provided is a novel compound and use thereof which has an excellent immunological regulation ability while not exhibiting toxicity in vivo, and has no nephrotoxicity and rather has a kidney protective effect, and thus can be used for the treatment of immune diseases such as autoimmune diseases caused by abnormal regulation of various immune responses, inflammatory diseases, and transplant rejection diseases. A transplant rejection avatar animal model was confirmed to be humanized, by confirming an increase in serum creatinine, an indicator of transplant rejection in a patient, an increase in human CD4-positive cells, and infiltration of inflammatory cytokine IL-17 into kidney tissue of the animal model. It was confirmed that, when an immunosuppressant is administered, the increased serum creatinine, human CD4-positive cells, and the infiltration of inflammatory cytokine IL-17 are reduced, and thus an animal model, in which the immune status of a patient is reflected, is effectively constructed.

Abstract: Disclosed is a surgical pin guide. To this end, the present invention provides a surgical pin guide including a guide fixed to an outer circumferential surface of a femur and configured to allow a center pin and a central pressure reducer of a drill handpiece to approach a necrotic region of an expanded area, a guide main body including a handle provided on an upper surface of a block, a center pin-guide hole horizontally pierced at a center of a front surface of the block, and a plurality of side pin-guide holes pierced at predetermined inclination angles with respect to the center pin-guide hole, arranged radially in the front surface of the block, and configured to meet the center pin-guide hole in a rear surface of the block, and a leading body configured to allow the guide main body to be detached from the guide and approach the necrotic region of the femoral head in a rotationally folded state.

Abstract: A dental medical record device and a dental medical record method, in which: an image, such as a panoramic photo, a scan image, and a camera image of a patient's oral cavity, is received via artificial intelligence, and charting is performed using the artificial intelligence; and medical records for a treatment area can be read in association with a chart by clicking the treatment area in the image.

Abstract: There is provided a method for determining dementia risk factors by a server using deep learning. In this instance, the method for determining dementia risk factors includes acquiring biometric information from each subject corresponding to a first control group through a wearable device, acquiring measurement information for each subject corresponding to the first control group, deriving a first dementia risk factor based on the biometric information and the measurement information for each subject, and deriving a second dementia risk factor related to the first dementia risk factor via deep learning performed based on the biometric information related to the first dementia risk factor and control group information.

Abstract: A bone tumor surgery device according to an embodiment of the present invention comprises: an accommodation container in which an accommodation space for accommodating a bone of a patient is formed; and a radiofrequency supply unit for supplying radiofrequency into the accommodation space.

Abstract: The present invention relates to a system and method for monitoring the safety of users in a shaded area, wherein location information about an RFID post installed in a shaded area is identified by means of an RFID tag, so that the location of a work group working in the shaded area can be transmitted to a control server in real time, and the control server compares the location of the work group with operation information about trains, thereby determining whether the work group is in danger or not, makes notification the same, so that the safety of the work group can be secured.

Abstract: The present invention relates to a composition which is for preventing or treating bone diseases and includes CCR2 as an active ingredient. It was confirmed that a C—C chemokine receptor type 2 (CCR2) protein, a polynucleotide encoding the CCR2 protein, or a mesenchymal stem cell transduced with the CCR2 according to the present invention neutralize bone disease factor MCP-1, thereby reducing the collagen epitope (CTX-II) and collagen metabolism factors (MMP1 and MMP3) relating to collagen absorption in the body. In addition, it was confirmed that the expression of the SOX9 gene and anti-inflammatory cytokines (TGF-? and IL-10) related to cartilage differentiation was significantly increased. Thus, the present invention has excellent regenerative ability against osteoarthritis and excellent pain suppression and alleviation effects, and thus can be effectively used for preventing or treating bone diseases such as osteoarthritis.

Abstract: A multilayer cornea harvesting apparatus capable of obtaining layers of cornea from one cornea enucleation object and a cornea harvesting method is disclosed. The apparatus includes a base supported on a bottom surface, a mount detachably coupled to the base, allowing a cornea enucleation object to be placed thereon, having a first opening part formed at a portion corresponding to the cornea of the cornea enucleation object, and having a first medicinal fluid charging space formed between the base and the mount, a stabilizer fixing, to the mount, a sclera portion of the cornea enucleation object placed on the mount and having a second opening part formed at a portion corresponding to the cornea, and an upper cover detachably provided on the upper side of the cornea, supported by the mount or supporting the mount, and forming a second medicinal fluid charging space on the upper side of the cornea.

Abstract: Provided is an artificial bladder including: a main body which includes an inlet port, an outlet port, and a predetermined reservoir portion configured to store urine between the inlet port and the outlet port and is formed of a biocompatible polymer that is expandable so that a volume of the reservoir portion changes according to the amount of urine; a sensor which is attached to an outer wall of the main body, has a surface having a wrinkled structure, and is provided so that, when the volume of the reservoir portion increases, the wrinkled structure stretches out and resistance of the sensor changes; and an actuator which is provided at the outlet port and is configured to discharge the urine according a result detected by the sensor.

Abstract: The present invention relates to an extensible drug injection device capable of injecting a drug from a location away from a patient, and an operation method therefor. Disclosed is a drug injection device comprising: a first sub-line of which one end joins with a main line, connected from a first drug storage part for storing a first drug to be injected into a patient to the body of the patient such that the first drug flows therein, and of which the other end is extended to the other side; a second drug injection part which is connected to the first sub-line and which injects a second drug that is different from the first drug; and a second drug pumping part which is connected to the first sub-line, and which pushes, to the main line, the second drug having been injected by the second drug injection part into the first sub-line.

Abstract: A hemostatic device is disclosed. The hemostatic device according to an embodiment of the present invention includes: a balloon which is expanded by a fluid supplied therein; a blood discharge pipe which includes a blood inflow hole at one end and exposes the other end to a lower side of the balloon wherein a certain section of a lower side of the blood inflow hole is surrounded by the balloon; and a fluid flow pipe communicating with the inside of the balloon for supplying or discharging the fluid and extending to a lower side of the balloon. The balloon includes a plurality of protrusions that are formed to protrude outward when the balloon is expanded by the fluid.

Abstract: The present invention relates to: a biomarker composition for diagnosing or predicting the prognosis of thyroid cancer, comprising a preparation capable of detecting a mutation in a PLEKHS1 promoter gene; and a use thereof. The biomarker composition for diagnosing or predicting the prognosis of thyroid cancer of the present invention confirms whether a mutation is present in a PLEKHS1 promoter gene, and thus can provide information needed for diagnosing metastatic (distant metastatic) differentiated thyroid cancer, and also confirms whether a mutation is present in BRAF, TERT promoter, three types of RAS and a TP53 gene in addition to the PLEKHS1 promoter gene, and thus, with respect to radioactive iodine therapy response and survival, can classify the prognosis of a metastatic differentiated thyroid cancer patient into one of three prognosis groups, and predict the same.

Abstract: Provided is a method for preventing or treating a retinal degenerative disease, comprising administering to a subject in need thereof human neural crest-derived nasal inferior turbinate stem cells as an active ingredient, in which the stem cells are differentiated into rod photoreceptor cells among photoreceptor cells expressing rhodopsin and prevent or treat a retinal degenerative disease including age-related macular degeneration.

Abstract: Provided is a medical test slide unit including a frame main body including: a marker part which has a thin plate shape and in which a plurality of position indicating markers are formed longitudinally and transversely; and a border part arranged to surround the marker part, wherein a step is formed between the border part and the marker part to form a seating recess, and wherein a slide, on which a specimen to be examined using a microscope is placed, is selectively seated in the seating recess.

Abstract: The present invention relates to an apparatus for patient-controlled drug injection having a counter capable of counting the number of administrations. According to one aspect of the present invention, disclosed is an apparatus for patient-controlled drug injection having a counter, comprising: a case; a pressing part, provided in the case, for applying pressure to pump a chemical liquid; and a counter, provided in the case and having a counting button that is pressed by pressure when a user presses the pressing part, for counting the number of times that the pressing part is pressed.