Patents Assigned to The Centre National de la Recherché Scientifique
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Patent number: 12084755Abstract: A process for coating a substrate with tantalum nitride by the high-power impulse magnetron sputtering technique, wherein a tantalum target is used and wherein the coating of the substrate is carried out in an atmosphere containing nitrogen, the bias of the target being controlled during the coating by imposing on it the superposition of a continuous bias at a potential between ?300 V and ?100 V and of a pulsed bias whose pulses have a potential between ?1200 V and ?400 V.Type: GrantFiled: May 14, 2020Date of Patent: September 10, 2024Assignees: SAFRAN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUXInventors: Marjorie Christine Cavarroc, Baptiste Simon Giroire, Lionel Teule-Gay, Angélique Poulon
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Patent number: 12083503Abstract: A process for preparing a catalyst material, includes the steps of: (a) providing a support material having surface hydroxyl (OH) groups, wherein the support material is ceria (CeO2), zirconia (ZrO2) or a combination of thereof; (b) reacting the support material having surface hydroxyl (OH) groups of step (a) with a precursor containing two transition metal atoms, each chosen independently from the group consisting of: W, Mo, Cr, Ta, Nb, V, Mn; (c) calcining the product obtained in step (b) in order to provide a catalyst material showing dual site surface species containing pairs of transition metal atoms derived from the precursor that are present in oxide form on the support material. Additionally, a catalyst material is obtained by the process set out above, and the catalyst material is used as an ammonia selective catalytic reduction (NH3-SCR) catalyst for nitrogen oxides (NOx) reduction.Type: GrantFiled: June 4, 2019Date of Patent: September 10, 2024Assignees: TOYOTA MOTOR EUROPE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLAUDE BERNARD LYON 1, ECOLE SUPERIEURE DE CHIMIE PHYSIQUE ELECTRONIQUE DE LYONInventors: Phuc Hai Nguyen, Marc-Olivier Charlin, Cherif Larabi, Kai Chung Szeto, Mostafa Taoufik
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Patent number: 12084608Abstract: The present invention relates to a new type of low-dimensional hybrid post-perovskites for high efficiency white light emission. More precisely, the invention relates to a one dimensional post-perovskite of formula AaMmXx·yH2O wherein A is a cis- or trans-2,5-dialkylpiperazine derivative bearing C1-C3 linear or branched alkyl groups, M is one or more metal, X one or more halogen, 0<a<5, 1<m<2, 2<x<12, 0<y. The invention also relates to material and luminescent device comprising the same and methods of preparation of the of low-dimensional hybrid post-perovskites.Type: GrantFiled: June 14, 2019Date of Patent: September 10, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTESInventors: Romain Gautier, Florian Massuyeau, Michael Paris
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Publication number: 20240295476Abstract: A method for characterizing a mechanical part making it possible to evaluate the residual stresses in the part, as well as a method for constructing a predictive model and a non-destructive testing method making it possible to easily test such a part, the characterizing method including the following steps: measuring geometrical information of the part in a first state, physically transforming the part between the first state and a second state, measuring geometrical information of the part in its second state, determining the displacement field between the first state and the second state of the part by a digital image correlation method and obtaining the deformation field between the first state and the second state of the part, determining the stress field in the second state of the part by a finite element simulation method.Type: ApplicationFiled: June 16, 2022Publication date: September 5, 2024Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NORMALE SUPERIEURE PARIS- SACLAY, SAFRAN, SAFRAN AIRCRAFT ENGINESInventors: Julien Paul SCHNEIDER-DIE-GROSS, Arturo MENDOZA QUISPE, Stéphane ROUX
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Publication number: 20240294880Abstract: The invention provides a clonal cell line derived from a liver cancer cell line, preferably derived from a Huh7 hepatocarcinoma cell line, engineered to produce and secrete viral particles containing pregenomic RNA of the hepatitis B virus (HBV), predominantly over DNA of HBV, to calibrate quantitative HBV RNA assays.Type: ApplicationFiled: February 29, 2024Publication date: September 5, 2024Applicants: Universite Claude Bernard Lyon 1, Centre National de la Recherche Scientifique, INSERM (Institut National de la Santé et de la Recherche Médicale), Hospices Civils De Lyon, Centre Leon BerardInventors: Massimo Levrero, Fabien Zoulim, Alexia Paturel
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Patent number: 12077767Abstract: The present invention relates to a genetically engineered plant in which the G-box motif has been inactivated, thereby inhibiting the thermosensory response, and methods for preparing such a plant.Type: GrantFiled: March 17, 2020Date of Patent: September 3, 2024Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Chloé Zubieta, Aditya Nayak
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Patent number: 12080955Abstract: The disclosed antenna includes: a radiating element disposed in a radiating plane transverse to an axis of the antenna; a reflecting plane, which is transverse to the axis, the radiating plane being located at a predetermined height above the reflecting plane; and a substrate, interposed between the radiating plane and the reflecting plane, and having a constant thickness. This antenna is characterized by a local relative electrical permittivity of the substrate that is a function of the radius, i.e. the distance to the axis, and a height, i.e. a distance to the reflecting plane, the local relative electrical permittivity being, at constant height, increasing as a function of the radius, and, at constant radius, increasing as a function of the height at least for a portion of the substrate in the vicinity of the reflecting plane.Type: GrantFiled: December 19, 2022Date of Patent: September 3, 2024Assignees: THALES, UNIVERSITE DE BRETAGNE OCCIDENTALE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Jefferson Champion, Stéphane Mallegol, Ismaël Pele, Erwan Goron, Jessica Benedicto, Noham Guy Philippe Martin, Rozenn Allanic, Cédric Quendo
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Patent number: 12080824Abstract: A method for producing an optoelectronic device having nitride-based microLEDs includes providing an assembly having at least one growth substrate and a nitride structure, where the nitride structure has a semipolar nitride layer that includes an active stack and crystallites extending from facets of the growth substrate with a crystalline orientation {111} to the first face of the semipolar nitride layer and providing an integrated control circuit featuring electric connection pads. The assembly is placed on the integrated control circuit, the growth substrate and the crystallites are removed, and trenches are formed in the stack so as to delimit a plurality of islets, each islet being configured to form a microLED.Type: GrantFiled: December 22, 2021Date of Patent: September 3, 2024Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Guy Feuillet, François Templier, Jesus Zuniga Perez, Philippe Vennegues
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Patent number: 12077744Abstract: The invention describes a device (10) for dispensing microbubbles (30) for cell sonoporation, comprising: a tube configured to receive a vial (20) containing a solution (26) of microbubbles (30), at least two catheters (11, 12) arranged inside the tube and opening into the vial (20) when the latter is received by the tube, wherein, when the first catheter (11) is connected to a first air injection source, air can be injected into the vial (20) via the first catheter so as to generate an overpressure therein, the microbubbles (30) contained in the vial (20) entering the second catheter (12) and moving toward its second end (122). The invention also relates to a sonoporation device, a sonoporation process and a computer program product.Type: GrantFiled: September 18, 2019Date of Patent: September 3, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE D'ORLEANSInventors: Anthony Delalande, Matthias Lebertre, Michaël Delalande, Chantal Pichon
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Patent number: 12076086Abstract: According to one aspect, the invention relates to a system (101) for in vivo, full-field interference microscopy imaging of a scattering three-dimensional sample.Type: GrantFiled: September 27, 2019Date of Patent: September 3, 2024Assignees: PARIS SCIENCES ET LETTRES—QUARTIER LATIN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), ECOLE SUPERIEURE DE PHYSIQUE ET CHIMIE INDUSTRIELLES DE LA VILLE DE PARISInventors: Viacheslav Mazlin, Peng Xiao, Mathias Fink, Albert Claude Boccara
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Publication number: 20240286178Abstract: Systems, methods, and compositions relating to pretreatment and enzymatic degradation of polymeric materials comprising one or more crystallizable polymers or copolymers are generally described. Certain aspects are directed to methods comprising reacting a polymeric material comprising a crystallizable polymer or copolymer with a reactive agent to produce a pretreated polymeric material and exposing the pretreated polymeric material to a polymer-degrading enzyme. In some embodiments, the reactive agent induces chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer. In some embodiments, the reactive agent induces chain scissions followed by chain extension, branching, and/or cross-linking of the crystallizable polymer or copolymer.Type: ApplicationFiled: January 9, 2024Publication date: August 29, 2024Applicants: Protein Evolution Inc, PARIS SCIENCES ET LETTRES, Centre National de la Recherche Scientifique, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS, SORBONNE UNIVERSITEInventors: Ludwik Leibler, François Tournilhac, Clément Freymond, Hernan Garate, Louise Bréloy, Andrew Griffiths, Yannick Rondelez, Brian Mansaku, Jack Pallis, Benjamin Gibbs
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Publication number: 20240287650Abstract: The invention relates to a nickel-based superalloy comprising in weight percentages: 5.0 to 6.0% of aluminium, 6.0 to 9.0% of tantalum, 1.0 to 5.0% of cobalt, 5.0 to 7.5% of chromium, 0 to 1.0% of molybdenum, 4.0 to 6.0% of tungsten, 0.50 to 3.5% of rhenium, 1.0 to 4.0% of platinum, 0.05 to 0.25% of hafnium, 0 to 0.15% of silicon, the remainder consisting of nickel and unavoidable impurities. The invention also relates to a single-crystal blade comprising such an alloy and to a turbomachine comprising such a blade.Type: ApplicationFiled: June 17, 2022Publication date: August 29, 2024Applicants: SAFRAN, SAFRAN AIRCRAFT ENGINES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE POITIERS, ECOLE NATIONALE SUPERIEURE D'ARTS ET METIERSInventors: Jérémy RAME, Jonathan CORMIER, Lorena MATAVELI SUAVE, Edern MENOU
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Patent number: 12071638Abstract: The present invention relates to variants of Terminal deoxynucleotidyl Transferase (TdT), each of which (i) has an amino acid sequence similarity to SEQ ID NO: 2. 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33 or 35 with corresponding amino acid substitutions, (ii) is capable of synthesizing a nucleic acid fragment without a template and (iii) is capable of incorporating a modified nucleotide into the nucleic acid fragment.Type: GrantFiled: December 7, 2021Date of Patent: August 27, 2024Assignees: DNA Script, Institut Pasteur, Centre National de la Recherche ScientifiqueInventors: Elise Champion, Mikhael Soskine, Thomas Ybert, Marc Delarue
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Patent number: 12072441Abstract: A device for measuring a physical quantity, including at least a transceiver unit for electromagnetic waves, an antenna-sensor including a sensor integrated into a target antenna having at least one excitation port, the antenna-sensor having a variable impedance with electromagnetic transduction, the measuring device being configured, per predetermined frequency band and independently of the angular difference between the transmission and reception of waves, for measuring the electromagnetic response of the antenna-sensor at least from an ellipticity rate of an electromagnetic field backscattered by the antenna-sensor, the ellipticity rate characterizing the polarization of the electromagnetic field configured to be measured by the transceiver unit, the electromagnetic response being representative, by electromagnetic transduction, of the at least one physical quantity to be measured.Type: GrantFiled: November 21, 2022Date of Patent: August 27, 2024Assignees: Commissariat à l'énergie atomique et aux énergies alternatives, Centre national de la recherche scientifiqueInventors: Luis-Felipe Fonseca-Dias, Camille Jouvaud, Christophe Delaveaud, Hervé Aubert
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Patent number: 12072282Abstract: A method for analysing a sample uses a resonant support having a surface on which a plurality of separated photonic crystals extends. At least two crystals are configured to capture the same analyte. A resonance wavelength associated with each crystal varies with an amount of analyte in contact with the crystal. The wavelengths define a resonance spectral band between 200-1500 nm. The transmission/reflection of the light is maximum at an associated resonance wavelength. The method includes: illuminating the support in the resonance spectral band, the intensity of the lamination being variable in band; acquiring a measurement image using an image sensor, the image having different regions-of-interest each optically coupled to a photonic crystal; using a reference image representative of an image acquired by the image sensor, when the support is illuminated in the resonance spectral band in a reference configuration; and comparing the measurement image with the reference image.Type: GrantFiled: June 4, 2020Date of Patent: August 27, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CPE LYON FORMATION CONTINUE ET RECHERCHE, ECOLE CENTRALE DE LYON, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVESITE CLAUDE BERNARD LYON 1, AVALUN, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Mathieu Dupoy, Taha Benyattou, Lotfi Berguiga, Jean-Marc Fedeli, Maryse Fournier, Nicolas Gaignebet, Cecile Jamois, Patrick Pouteau
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Patent number: 12071671Abstract: Disclosed is a method for in vitro predicting the outcome of an individual having a multiple myeloma, including: —a) measuring the expression level of at least 2 genes encoding a ROS detoxifying (AOX) protein selected in a group including AKR1 B1, ARNT, CAT, CBR1, DHCR24, EGLN1, GLRX2, HIF1A, MGST1, MSRB1, PRDX6, SLC7A11, SOD1, SRXN1, TALDO1 and TXN and/or the expression level of at least 2 genes encoding ROS producing (ROS) protein selected in a group including CYBA, CYB5A, CYC1, NCF1B, NCF1C, NCF4, NDUFA12, NDUFS2, NDUFS8, SHC1 and UQCR10, in a biological sample obtained from the individual; —b) calculating an AOX score value and/or a ROS score value from the respective expression level(s) obtained at step a); —c) classifying the individual as having a good prognosis status or a bad prognosis status, by comparing the score value obtained at step b) with a reference score value.Type: GrantFiled: February 7, 2019Date of Patent: August 27, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER, CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIERInventors: Alboukadel Kassambara, Jérôme Moreaux, Wafa Hassen
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Patent number: 12071658Abstract: The subject matter of the present invention is a microfluidic process for treating and analysing a solution containing a biological material, comprising a step of introducing the solution into microchannels of a microfluidic circuit (1), a step of forming drops of this solution, under the effect of modifications of the surface tension of the solution, a step of moving the drops to one or more drop storage zones(s) (130), under the effect of modifications of the surface tension of the drops, a step of treating the drops and a step of analysing the drops.Type: GrantFiled: July 19, 2021Date of Patent: August 27, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ÉCOLE POLYTECHNIQUEInventors: Charles Baroud, Rémi Dangla, Paul Abbyad, Silvan Turkcan
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Publication number: 20240279067Abstract: A sensor device including a conductive graphene film covered on at least one side by a graphene support layer of parylene, a detection element configured to sense an environmental change, and an electrode. The parylene repairs some defects of the conductive graphene film without damaging, polluting, or degrading the conductivity of conductive graphene film.Type: ApplicationFiled: May 2, 2024Publication date: August 22, 2024Applicants: Centre National de la Recherche Scientifique, UNIVERSITE GRENOBLE ALPESInventors: Dipankar KALITA, Vincent BOUCHIAT, Laetitia MARTY, Nedjma BENDIAB
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Publication number: 20240277208Abstract: The method for imaging an object to be imaged includes: generating, using a lighting device (2), a series of illumination patterns; for each illumination pattern, carrying out a stimulating phase in which translations of the illumination pattern are carried out over an entrance of a square-core multimode optical fiber (4) by means of at least one translating device (3a) of an optical system (3) placed between the lighting device (2) and the entrance of the square-core multimode optical fiber (4), the translations being carried out in a plane parallel to the entrance plane of the square-core multimode optical fiber (4); for each stimulating phase, carrying out an acquiring phase in which the signal generated by the illumination pattern on the object to be imaged (O) placed at the exit of the square-core multimode optical fiber (4) is measured by a signal-measuring device (5; 9); and reconstructing, using a computing device (6), by the signal measured in each acquiring phase, the object to be imaged.Type: ApplicationFiled: June 20, 2022Publication date: August 22, 2024Applicants: UNIVERSITE GRENOBLE ALPES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Emmanuel Bossy, Antonio Miguel Caravaca Aguirre
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Publication number: 20240282891Abstract: A light emitting device including a solid fluorescent material or a solid scintillator material adapted to absorb an incident light and then emit a luminescent light in the material, a portion, called trapped portion, of the luminescent light being trapped by total internal reflections in the material, the material including two parallel faces, called large faces, along an horizontal plane xy, and n?N>2 faces called side faces, and forming vertex between two adjacent side faces and a large face. The material has an invariance of the normals to said side faces by rotation by an angle of 2?/n in said horizontal plan around a z-axis perpendicular to the horizontal plane. The material has a vertex called virtual vertex that is beveled thus forming a surface called beveled vertex, or the material has an edge between two side faces.Type: ApplicationFiled: June 15, 2022Publication date: August 22, 2024Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-SACLAY, INSTITUT D'OPTIQUE THEORIQUE ET APPLIQUEEInventors: François BALEMBOIS, Pierre PICHON