Patents Assigned to The Cielo Institute, Inc.
  • Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins
    Publication number: 20050119454
    Abstract: Methods of synthesizing a peptide or peptide-like molecule to a polypeptide or protein target based on mode-matching each member of a set of peptide constituents of the peptide or peptide-like molecule to peptide constituents of the target polypeptide or protein target for treatment of neurological diseases.
    Type: Application
    Filed: April 2, 2004
    Publication date: June 2, 2005
    Applicant: The Cielo Institute, Inc.
    Inventors: Arnold Mandell, Karen Selz, Michael Shlesinger
  • Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins
    Patent number: 6865492
    Abstract: Methods of synthesizing a peptide or peptide-like molecule to a polypeptide or protein target based on mode-matching each member of a set of peptide constituents of the peptide or peptide-like molecule to peptide constituents of the target polypeptide or protein target. Methods are also provided for synthesizing retro-inverso peptides to the mode-matched peptide.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: March 8, 2005
    Assignee: The Cielo Institute, Inc.
    Inventors: Arnold J. Mandell, Karen A. Selz, Michael F. Shlesinger