Patents Assigned to The City University
  • Patent number: 11971951
    Abstract: Systems and methods which provide a motion sensor data-driven framework for sports action recognition and/or assessment using a wearable sensor are described. A motion sensor data-driven system may provide real-time kinematical analysis to athletes engaged in active competition or training sessions under typical competition or training conditions. Analysis of motion sensor data provided according to embodiments may operate to recognize instances of one or more particular sports actions performed by an athlete and/or assess the skill of the athlete from analysis of one or more sports actions. A motion sensor data processing platform of embodiments of a motion sensor data-driven system may comprise a processor-based system configured to receive and analyze data regarding the movement of an athlete's limb reported by a wearable sensor device comprising a micro inertial measurement unit configuration for capturing and reporting data regarding the movement of an athlete's limb.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: April 30, 2024
    Assignee: City University of Hong Kong
    Inventors: Yufan Wang, Wen Jung Li, Ho Man Chan, Guanglie Zhang
  • Publication number: 20240132887
    Abstract: Disclosed herein are, inter alia, inhibitors of protein arginine methyltransferase 9 and pharmaceutical compositions thereof, and methods comprising the use of protein arginine methyltransferase 9 inhibitors for the treatment of a protein arginine methyltransferase 9-modulated disease or disorder, such as a hematological cancer.
    Type: Application
    Filed: October 6, 2023
    Publication date: April 25, 2024
    Applicants: City of Hope, Western University of Health Sciences
    Inventors: Ling Li, Haojie Dong, Lei Zhang, Xin He, Yun Lyna Luo, Yi-Chun Lin
  • Patent number: 11968904
    Abstract: The present invention provides a flexible piezoelectric composite including a three-dimensional interconnected piezoelectric ceramic framework based on a porous organic template with sufficient stiffness and infiltrated with a flexible polymer matrix. A method for fabricating the flexible piezoelectric composition is also described herein.
    Type: Grant
    Filed: July 5, 2021
    Date of Patent: April 23, 2024
    Assignee: City University of Hong Kong
    Inventors: Zhengbao Yang, Ying Hong
  • Patent number: 11963788
    Abstract: The present invention provides a graph-based prostate diagnosis network (GPD-Net) and a method for using the same to predict a prostate health status of a patient from a 3D magnetic resonance imaging (MRI) scan containing a plurality of 2D MRI slices. The GPD-Net only demands patient-level annotations of MRI scan for training by formulating the diagnosis task of 3D prostate MRI scan in a multi-instance learning (MIL) strategy, and regarding each 2D MRI slice in the 3D prostate MRI scan as an instance. The GPD-Net includes a plurality of importance-guided graph convolutional layers to explore the diagnostic information with the importance-based topology. The present invention provides accurate prediction of prostate diseases and achieve more reliable diagnosis from MRI scans, therefore can effectively alleviate the workload of clinician in viewing the slices of MRI scan.
    Type: Grant
    Filed: December 17, 2021
    Date of Patent: April 23, 2024
    Assignee: City University of Hong Kong
    Inventors: Yixuan Yuan, Zhen Chen
  • Patent number: 11968769
    Abstract: A dielectric barrier discharging tube, which has a synergistic column of needle electrodes to utilize a plurality of channels to adsorb catalysts, is provided. The dielectric barrier discharging tube includes: a quartz tube, a high-voltage pole, an inner electrode, and a plurality discharging needle sets. Two catalytic blocks are arranged respectively on two sides of each set discharging needles. Each catalytic block defines at least one inclined inner channel and at least one inclined outer channel. A higher end of each channel faces towards the discharging needle, and a lower end of each channel faces towards the discharging needle.
    Type: Grant
    Filed: December 21, 2023
    Date of Patent: April 23, 2024
    Assignee: HANGZHOU CITY UNIVERSITY
    Inventors: Qi Qiu, Pengfei Wang, Qinmin Yang, Hao Chen
  • Publication number: 20240125767
    Abstract: The present invention provides drug toxicity evaluation platforms (such as an evaluation method and a kit therefor) that enable detailed analysis of the possibility and the like of developing drug-induced damage (such as DILI) to the liver and other organs. The method for evaluating drug toxicity of the present invention includes: a step of adding a drug to a co-culture system of an organoid and blood cells; and a step of evaluating the toxicity of the drug to the organoid.
    Type: Application
    Filed: October 16, 2020
    Publication date: April 18, 2024
    Applicants: Public University Corporation Yokohama City University, Takeda Pharmaceutical Company Limited
    Inventors: Takanori TAKEBE, Norikazu SAIKI
  • Patent number: 11958869
    Abstract: Disclosed herein are ruthenium arene Schiff-base complex and uses thereof. The ruthenium arene Schiff-base complex disclosed herein has the structure of formula (I), wherein, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, and R12 are independently H, alkyl, alkoxyl, or halo; R13, R14, R15, R16, and R17 are independently H, alkyl, alkoxyl, hydroxy, halo, —C(?NH)NH2, —SO3H, —SO2NH2, —NR?R?, or —CONH2; or R13 and R14 are taken together to form a benzene ring, while R15, R16, and R17 are independently H, alkyl, alkoxyl, hydroxy, halo, —C(?NH)NH2, —SO3H, —SO2NH2, —NR?R?, or —CONH2; or R14 and R15 are taken together to form a benzene ring, while R13, R16, and R17 are independently H, alkyl, alkoxyl, hydroxy, halo, —C(?NH)NH2, —SO3H, —SO2NH2, —NR?R?, or —CONH2; R? and R? are independently H or alkyl; the alkyl is optionally substituted with one or more halo or hydroxy, or hydroxy; and Y is a counter anion. Also disclosed herein are methods of treating malignant neoplasm in a subject.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: April 16, 2024
    Assignee: CITY UNIVERSITY OF HONG KONG
    Inventors: Maria Babak, Wee Han Ang, Mun Juinn Chow
  • Patent number: 11961618
    Abstract: The present invention provides a task interaction network which can jointly perform, based on multi parametric-magnetic resonance imaging scan images, a segmentation task to locate prostate cancer areas and a classification task to access aggressiveness of lesions. The task interaction network comprises a backbone network, an auxiliary segmentation branch, a classification branch having a lesion awareness module, and a main segmentation branch having a category allocation module. The auxiliary segmentation branch is utilized to predict an initial lesion mask as location guidance information for the classification branch to perform the classification task. The lesion awareness module is configured to refine the initial lesion mask to make it more accurate. Moreover, weights used in classification branch can serve as the category prototypes for generating category guidance features via the category allocation module to assist the main segmentation branch to perform the segmentation task.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: April 16, 2024
    Assignee: City University of Hong Kong
    Inventors: Yixuan Yuan, Meilu Zhu
  • Patent number: 11958620
    Abstract: The present disclosure relates to a hydrogen electric hybrid power plant for a hovercar. The hydrogen electric hybrid power plant comprises a first-stage duct, a transition duct and a second-stage duct. An air outlet end of the first-stage duct is connected to the second-stage duct through the transition duct. A hydrogen reactor is arranged in the first-stage duct, and the hydrogen reactor is fixed with the first-stage duct through a plurality of supporting pieces A. A primary filter screen is arranged at a front end of the first-stage duct and fixed on the first-stage duct through a hoop, so that low-altitude sundries and dust are prevented from entering the reactor. A return pipe is arranged, and the problems of oxygen supply, heat dissipation and cooling and the like of the hydrogen reactor are solved through ducted airflow. A motor power supply requirement of a ducted fan is met.
    Type: Grant
    Filed: May 16, 2023
    Date of Patent: April 16, 2024
    Assignee: HANGZHOU CITY UNIVERSITY
    Inventor: Xinfeng Zhang
  • Patent number: 11962259
    Abstract: A drive system is disclosed which applies to a six-phase integrated permanent magnet synchronous motor. The motor includes a set of six-phase half-bridge drive system and a thermistor monitoring system for monitoring the temperature of the six-phase half-bridge drive system. Aiming at the problem that the six-phase drive system is complicated and has many components, the invention adopts a grouping method to divide the six-phase drive system into two sets of three-phase drive half-bridges. To provide stability for long term operation, a thermistor is used to accurately measure the temperature changes.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: April 16, 2024
    Assignee: CITY UNIVERSITY OF HONG KONG
    Inventors: Chunhua Liu, Senyi Liu
  • Publication number: 20240115873
    Abstract: The ultraviolet therapy apparatus includes a light source part having an LED light source, a controller that controls lighting of the LED light source, an input unit that inputs a set irradiation dose of a therapeutic light to be applied to a patient on the assumption that a reference light is used for the therapeutic light, a storage unit that stores at least one parameter for modifying the set irradiation dose. The controller includes a modifier that modifies the set irradiation dose on the basis of the parameter stored in the storage unit, and a lighting controller that causes the LED light source to provide the modified irradiation dose. The modified irradiation dose is derived from a degree of effect of the reference light on a human body and a degree of effect on the human body caused by the ultraviolet light output from the light source part.
    Type: Application
    Filed: December 9, 2021
    Publication date: April 11, 2024
    Applicants: PUBLIC UNIVERSITY CORPORATION NAGOYA CITY UNIVERSITY, USHIO DENKI KABUSHIKI KAISHA
    Inventors: Akimichi MORITA, Takashi HORIO, Tomohiko KIO, Hiroshi SHIBATA
  • Patent number: 11951229
    Abstract: To provide a liquid medical material maintaining a colloid in a more sol form than a solid at normal temperature, having a higher function as a wound dressing material and a hemostatic material than fibrin glue, and being able to be produced safely and inexpensively. A gelatin aqueous solution including calcium at a concentration of 0.2 M or more and 1.0 M or less, and having a concentration of 5% by weight or more and 40% by weight or less, an average molecular weight of 80,000 or more and 120,000 or less, and a molecular weight distribution of 20,000 or more and 300,000 or less, and transglutaminase inducing crosslinking of the gelatin, are included. It is preferable that the calcium has a concentration of 0.2 M or more and 0.7 M or less, the gelatin has a bloom of 160 or more and 250 or less, and the transglutaminase has activity per unit of 36 U/ml to 400 U/ml.
    Type: Grant
    Filed: August 20, 2021
    Date of Patent: April 9, 2024
    Assignees: AOBAKASEI KABUSHIKI KAISHA, OSAKA CITY UNIVERSITY IN UNIVERSITY PUBLIC CORPORATION OSAKA
    Inventors: Hirotsugu Kido, Katsunori Chiba, Hironori Arima, Kenji Ohata
  • Patent number: 11951272
    Abstract: A cryo formulation-based microneedle device for ocular delivery of bioactive therapeutic agents. The microneedle device includes: one or more microneedle patches each including an array of miniaturized needles, wherein each miniaturized needle defining a base end and a tip; and a substrate to which the base end of the array of miniaturized needles is attached or integrated thereto; wherein the microneedle patch is in a cryo status; wherein each of the one or more microneedle patch is adapted to be applied on cornea of an eye, in which the miniaturized needles penetrates into the eye; and wherein the miniaturized needles is further arranged to melt so as to release one or more bioactive therapeutic agents into the eye to achieve a targeted therapeutic effect.
    Type: Grant
    Filed: July 27, 2021
    Date of Patent: April 9, 2024
    Assignee: City University of Hong Kong
    Inventors: Chenjie Xu, Hao Chang
  • Patent number: 11952728
    Abstract: A road structure reconstructed from large-scale independent underground garage and a construction method, which solves the problem of a newly constructed urban expressway passing through large underground space. The technical point is a construction method for the road structure reconstructed from large-scale independent underground garage, including the following steps: S100: segmentation for the garage, S200: preparation before construction: the materials and equipment required for construction are transported to the site, and the construction site is cleaned, S300: reconstruction for the front section, S400: reconstruction for the middle section, S500: reconstruction for the rear section. The inventiveness of the present disclosure is the application of segmentation construction, the front section is completely obsoleted, a transition section is provided at the middle, and the design of the rear section adopts a double-deck road, thus the original underground garage structure is fully utilized.
    Type: Grant
    Filed: July 12, 2023
    Date of Patent: April 9, 2024
    Assignee: HANGZHOU CITY UNIVERSITY
    Inventors: Gang Wei, Tianbao Xu, Jiaxuan Zhu, Yunliang Cui, Bing Li, Ke Wang, Pengfei Xiang, Shuangyan Lin, Xinquan Wang, Hongguo Diao
  • Patent number: 11955627
    Abstract: A novel anode for a zinc battery is proposed, in which zinc is provided as a coat of zinc powder onto a tin substrate, which is in turn laid over a copper substrate for a current collector. Alternatively, the coat of zinc powder is laid over titanium as the current collector. Such configurations mitigate zinc corrosion and hydrogen production.
    Type: Grant
    Filed: January 20, 2022
    Date of Patent: April 9, 2024
    Assignee: CITY UNIVERSITY OF HONG KONG
    Inventors: Chunyi Zhi, Qing Li
  • Patent number: 11954254
    Abstract: An electrotactile apparatus has an electrode-array unit and a driver unit for generating a haptic feedback to a user. The electrode-array unit uses electrodes to electro-stimulate the user's skin with pulsed voltage signals generated by the driver unit, inducing excitation currents flowing in the user to generate the haptic feedback. The driver unit is self-powered or wirelessly powered for supporting untethered electrotactile stimulation to the user. A common counter electrode installed on the driver unit contacts the user's skin and collects the excitation currents returned from the user. Advantageously, the common counter electrode is located on an outer surface of the driver unit and the driver unit is substantially flexible, facilitating the common counter electrode to seamlessly contact the user's skin for achieving a stable electrode-skin interface while positioning the driver unit as a whole on the user's skin to provide untethered virtual touching experience to the user.
    Type: Grant
    Filed: April 22, 2022
    Date of Patent: April 9, 2024
    Assignee: City University of Hong Kong
    Inventors: Xinge Yu, Kuanming Yao, Jingkun Zhou
  • Patent number: 11955733
    Abstract: The present invention provides a new wideband mm-wave end-fire magneto-electric dipole antenna with excellent beam-scanning radiation patterns and reasonably low side lobes and low cross polarizations. The antenna comprises: an asymmetrical substrate integrated coaxial line feed comprising: a first substrate having a first substrate thickness; a second substrate placed on the first substrate and having a second substrate thickness different from the first substrate thickness; a conductive signal line deposited on an upper surface of the first substrate; and two rows of waveguiding vias positioned along and at both sides of the signal line respectively; a ?-shaped probe adopted to excite the antenna; a pair of shorted planar parallel plates serving as magnetic dipole and two pair of vertical conductive vias serving as electric dipole; and a folded vertical reflector consisting of conductive vias and strips is added to reduce the back radiation and to improve the gain of antenna.
    Type: Grant
    Filed: September 2, 2021
    Date of Patent: April 9, 2024
    Assignee: City University of Hong Kong
    Inventors: Kwai Man Luk, Ao Li
  • Publication number: 20240110153
    Abstract: The present invention relates to methods modifying cell surface markers of red blood cells (RBCs) and uses of the same. In particular, the method comprises contacting an RBC with a peptide in the presence of a ligase, under suitable conditions and for sufficient time to allow ligation of the peptide to the RBC to form an RBC-peptide conjugate. In one embodiment, the ligase is OaAEPI ligase. The RBC-peptide conjugate may be further contacted with an effector molecule under suitable conditions and for sufficient time for conjugation of the effector molecule to the RBC-peptide to form an RBC-peptide-effector molecule conjugate.
    Type: Application
    Filed: January 28, 2022
    Publication date: April 4, 2024
    Applicants: NATIONAL UNIVERSITY OF SINGAPORE, CITY UNIVERSITY OF HONG KONG
    Inventors: Thi Nguyet Minh LE, Migara Kavishka JAYASINGHE, Boya PENG, Jiahai SHI
  • Patent number: 11945774
    Abstract: The present disclosure provides a bimetallic coordination metal-organic framework material, a preparing method thereof, and an application thereof. In the bimetallic coordination metal-organic framework material, carboxyl groups and soft groups of ligands are coordinated with coordination metal ions to assemble a structure having space and functions divided into covalent charge carrier layers and charge storage ion layers. Further, through the conjugation effect, the bimetallic coordination metal-organic framework material has unique electromagnetic properties, good electrical conductivity, and magnetic coupling performance. Thus, the bimetallic coordination metal-organic framework material is used as superconducting materials, conductive materials, semiconductor materials, or electromagnetic materials.
    Type: Grant
    Filed: February 14, 2023
    Date of Patent: April 2, 2024
    Assignees: GUANGDONG UNIVERSITY OF TECHNOLOGY, CITY UNIVERSITY OF HONG KONG
    Inventors: Jun He, Jieying Hu, Liangming Tang, Zhiqing Liu, Xinhe Ye, Gengyuan Zhang, Zhengtao Xu
  • Patent number: 11949117
    Abstract: A battery includes a plurality of energy storage units, a flexible linkage arranged to physically and electrically connect each adjacent pair of energy storage units, and an encapsulation arranged to encapsulate the energy storage units and the linkages. The energy storage units are movable with respect to each other via the flexible linkage within each adjacent pair of energy storage units in the encapsulation.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: April 2, 2024
    Assignee: City University of Hong Kong
    Inventors: Chunyi Zhi, Ao Chen, Zijie Tang