Abstract: The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.
Type:
Grant
Filed:
September 24, 2010
Date of Patent:
March 15, 2016
Assignees:
The CONRAD Program of the Eastern Virginia Medical School (“CONRAD”), International Partnership for Microbicides, Inc.
Abstract: The present invention relates to formulations of nucleotide reverse transcriptase inhibitors (NRTIs), preferably [2-(6-Amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid (tenofovir, PMPA), or a physiologically functional derivative thereof, suitable for topical application and their use in the prevention of HIV infections.
Type:
Grant
Filed:
September 29, 2010
Date of Patent:
June 23, 2015
Assignees:
The CONRAD Program of the Eastern Virginia Medical School (“CONRAD”), International Partnership for Microbicides, Inc.