Abstract: The present invention provides cytotoxic Epstein-Barr virus T-cell epitopes. These epitopes are QVKWRMTTL, VFSDGRVAC, VPAPAGPIV, TYSAGIVQI, LLDFVRFMGV, QNGALAINTF, VSSDGRVAC, VSSEGRVAC, VSSDGRVPC, VSSDGLVAC, VSSDGQ-VAC, VSSDGRVVC, VPAPPVGPIV, VEITPYEPIG, VEITPYEPTW, VELTPYKPTW, RRIYDLIKL, RKIYDLIEL and PYLFWLAGI. The present invention further provides vaccines including one or more of these epitopes, optionally with additional epitopes.
Type:
Application
Filed:
August 1, 2001
Publication date:
October 17, 2002
Applicant:
The Council of the Queensland Institute of Medical Research, CSL Limited
Inventors:
Rajiv Khanna, Beverley Mavis Kerr, Ihor Stephan Misko, Denis James Moss, Scott Renton Burrows