Abstract: The invention features methods for inhibiting immunostimulatory DNA-associated immune responses, through the administration of specific compounds of the general class of 9-aminoacridines and 4-aminoquiniolines. The invention also features methods of screening compounds useful in inhibiting immunostimulatory DNA-induced immune responses.
Type:
Grant
Filed:
January 3, 2003
Date of Patent:
April 8, 2008
Assignees:
University of Iowa Research Foundation, The Department of Veterans Affairs, as represented by the Secretary of United States of America