Abstract: The present invention relates to compositions and methods for detecting and inhibiting squamous cell carcinoma using agents that target the laminin 5 alpha 3 G4-G5 domain.
Type:
Grant
Filed:
April 14, 2008
Date of Patent:
January 25, 2011
Assignees:
The Dept. of Veterans Affairs Office of The General Counsel, The Board of Trustees of the Leland Stanford Junior University
Abstract: The present invention is directed to methods and compositions related to &agr;7 acetylcholine nicotinic receptor genes, in particular, the human &agr;7 nicotinic acetylcholine receptor gene. The human &agr;7 nicotinic acetylcholine receptor gene is associated with the pathophysiological aspects of the disease schizophrenia. The present invention further provides methods and compositions to screen populations for abnormal &agr;7 alleles, as well as methods and compositions for development of therapeutics.
Type:
Application
Filed:
November 26, 2003
Publication date:
September 23, 2004
Applicant:
The U. S. A. as represented by the Dept. of Veterans Affairs, Office of General Counsel