Patents Assigned to The DuPont Merck Pharmaceutical Co.
  • Patent number: 5324824
    Abstract: A method for preparing a coordination complex of an isonitrile ligand and a radioisotope of Tc, Ru, Co, Pt, Re, Os, Ir, W, Re, Cr, Mo, Mn, Ni, Rh, Nb and Ta from a non-radioactive metal adduct of the isonitrite.
    Type: Grant
    Filed: March 12, 1991
    Date of Patent: June 28, 1994
    Assignee: The DuPont Merck Pharmaceutical Co.
    Inventors: Alan B. Carpenter, Jr., Leo J. Maheu, Michael A. Patz, Thomas H. Tulip, Karen E. Linder, Vinayakam Subramanyam, Jeffery S. Thompson
  • Patent number: 5317024
    Abstract: Novel unsaturated ether derivatives of alkyl piperidine and pyrrolidine compounds, pharmaceutical compositions containing them, methods of preparation and methods of using these compounds as antipsychotic agents are disclosed.
    Type: Grant
    Filed: August 3, 1993
    Date of Patent: May 31, 1994
    Assignee: DuPont Merck Pharmaceutical Co.
    Inventors: Gary A. Cain, Thomas E. Christos, Sang W. Tam
  • Patent number: 5296478
    Abstract: Compounds of Formula I have been shown to enhance the release of the neurotransmitter acetlcholine, and thus may be useful as chemical intermediates and as pharmacological agents in the treatment of diseases of man, such as in Alzheimer's Disease and other conditions involving learning and cognition, where subnormal levels of this neurochemical are found.
    Type: Grant
    Filed: October 7, 1992
    Date of Patent: March 22, 1994
    Assignee: The DuPont Merck Pharmaceutical Co.
    Inventor: Christopher A. Teleha
  • Patent number: 5294720
    Abstract: There are provided novel 1,4 Diamine 2,3 Dihydroxybutanes useful as antiviral agents, pharmaceutical compositions containing them and processes for preparing such compounds.
    Type: Grant
    Filed: May 31, 1991
    Date of Patent: March 15, 1994
    Assignee: The DuPont Merck Pharmaceutical Co.
    Inventors: Prabhakar K. Jadhav, Lawrence R. McGee, Ashok Shenvi, Carl N. Hodge
  • Patent number: 5173489
    Abstract: Cognitive defeciencies or neurological dysfunction in mammals are treated with .alpha.,.alpha.-disubstituted aromatic or heteroaromatic compounds. The compounds have the formula: ##STR1## or a salt thereof wherein X and Y are taken together to form a saturated or unsaturated carbocyclic or heterocyclic first ring and the shown carbon in said ring is .alpha. to at least one additional aromatic ring or heteroaromatic ring fused to the first ring;one of Het.sup.1 is 2, 3 or 4-pyridyl or 2, 4, or 5-pyrimidinyl and the other is selected from(a) 2, 3, or 4-pyridyl,(b) 2, 4, or 5-pyrimidinyl,(c) 2-pyrazinyl,(d) 3, or 4-pyridazinyl,(e) 3, or 4-pyrazolyl,(f) 2, or 3-tetrahydrofuranyl, and(g) 3-thienyl.
    Type: Grant
    Filed: August 23, 1988
    Date of Patent: December 22, 1992
    Assignee: The DuPont Merck Pharmaceutical Co.
    Inventors: Richard A. Earl, Melvyn J. Myers, Victor J. Nickolson