Abstract: A radioimmunoconjugate for targeted alpha therapy comprises an alpha-emitter (e.g. Bi-213) linked to the monoclonal antibody C595. This radioimmunoconjugate is widely applicable in cancer therapy and is particularly efficient for treatment of pancreatic and prostate cancer, as well as for breast and ovarian cancer.
Type:
Grant
Filed:
July 29, 2004
Date of Patent:
December 15, 2009
Assignee:
The European Community, as Represented by the European Commision
Inventors:
Barry Allen, Syed Rizvi, Yong Li, Chang Fa On